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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Nuestro objetivo ha sido determinar qu&#233; factores se relacionan con el desarrollo de engrosamiento pleural residual &#40;EPR&#41; al finalizar el tratamiento espec&#237;fico&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se estudian 62 pacientes diagnosticados de tuberculosis pleural &#40;TP&#41;&#44; separados en 2 grupos en funci&#243;n de la presencia o ausencia de EPR &#62; 2 mm en la porci&#243;n lateral e inferior de una radiograf&#237;a posteroanterior de t&#243;rax&#44; al finalizar el tratamiento espec&#237;fico&#46; Ning&#250;n paciente recibi&#243; corticoides&#46; El 72&#44;6&#37; present&#243; engrosamiento&#44; siendo este m&#225;s frecuente entre los varones &#40;<span class="elsevierStyleItalic">odds ratio</span>&#44; 4&#44;06&#59; p &#61; 0&#44;034&#41;&#44; y en los enfermos de edad media superior&#44; 36 &#177; 21 frente a 27 &#177; 12 a&#241;os &#40;p &#61; 0&#44;05&#41;&#46; El h&#225;bito tab&#225;quico&#44; tama&#241;o del derrame&#44; duraci&#243;n de la sintomatolog&#237;a&#44; encapsulamiento&#44; PPD&#44; biopsia pleural&#44; bacteriolog&#237;a y el pH&#44; glucosa&#44; prote&#237;nas y colesterol del l&#237;quido pleural&#44; as&#237; como sus respectivos cocientes pleura&#47;suero fueron similares en ambos grupos&#46; La LDH pleural &#40;LDHp&#41; y su relaci&#243;n pleura&#47;suero &#40;LDHp&#47;s&#41; fue 454&#44;3 &#177; 234&#44;6 U&#47;l y 3&#44;21 &#177; 1&#44;67 en el grupo con EPR&#44; por 306&#44;0 &#177; 137&#44;2 U&#47;l y 2&#44;00 &#177; 1&#44;16 del grupo sin secuelas &#40;p &#61; 0&#44;004 y p &#61; 0&#44;016&#44; respectivamente&#41;&#46; Utilizando como punto de corte una LDH p&#47;s superior a 2&#44;10&#44; la sensibilidad obtenida fue del 78&#44;9&#37; con especificidad del 71&#44;4&#37;&#44; valor predictivo positivo del 88&#44;2&#37; y valor predictivo negativo del 55&#44;5&#37;&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Concluimos que&#58; <span class="elsevierStyleItalic">a&#41;</span> el EPR es una complicaci&#243;n frecuente&#59; <span class="elsevierStyleItalic">b&#41;</span> de predominio masculino&#59; <span class="elsevierStyleItalic">c&#41;</span> que guarda relaci&#243;n con la edad&#44; y <span class="elsevierStyleItalic">d&#41;</span> un valor superior a 2&#44;10 en la relaci&#243;n LDH p&#47;s puede predecir con aceptable seguridad la presencia de este trastorno&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We aimed to determine which factors were related to the development of residual pleural thickening &#40;RPT&#41; after completion of prescribed treatment&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Sixty-two patients with pleural tuberculosis &#40;PTB&#41; were assigned to 2 groups according to the presence or absence of RPT &#62; 2 mm in the side and lower portion of a chest film after completion of prescribed treatment&#46; No patient had been given corticoids&#46; Thickening developed in 72&#46;6&#37;&#44; more often in men &#40;OR&#44; 4&#46;06&#59; p &#61; 0&#46;034&#41;&#44; in older patients &#40;36 &#177; 21 versus 27 &#177; 12 years&#59; p &#61; 0&#46;05&#41;&#46; Smoking&#44; size of effusion&#44; duration of symptoms&#44; encapsulation&#44; PPD&#44; pleural biopsy&#44; bacteriology and pH&#44; glucose&#44; proteins and cholesterol in pleural fluids&#44; as well as their respective pleura&#47;serum coefficients&#44; were similar in both groups&#46; Pleural LDH &#40;LDHp&#41; and its pleura&#47;serum coefficient &#40;LDHp&#47;LDHs&#41; were 454&#46;3 &#177; 234&#46;6 U&#47;l and 3&#46;21 &#177; 1&#46;67 U&#47;l in the group with RPT and 306&#46;0 &#177; 137&#46;2 U&#47;l and 2&#46;00 &#177; 1&#46;16 in the group with no sequelae &#40;p &#61; 0&#46;004 and p &#61; 0&#46;016&#44; respectively&#41;&#46; Using 2&#46;10 as the cutoff for LDHp&#47;LDHs&#44; sensitivity was 78&#46;9&#37; and specificity was 71&#46;4&#37;&#44; giving a positive predictive value of 88&#46;2&#37; and a negative predictive value of 55&#46;5&#37;&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We conclude that RPT <span class="elsevierStyleItalic">a&#41;</span> is a frequent complication&#44; <span class="elsevierStyleItalic">b&#41;</span> is mainly found in men&#44; <span class="elsevierStyleItalic">c&#41;</span> is age-related and <span class="elsevierStyleItalic">d&#41;</span> can be fairly safely predicted using 2&#46;10 as the cutoff for LDHp&#47;LDHs&#46;</p></span>"
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Vol. 31. Issue 4.
Pages 157-161 (April 1995)
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Vol. 31. Issue 4.
Pages 157-161 (April 1995)
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Engrosamiento pleural en el derrame pleural tuberculoso. Factores asociados
Pleural thickening in tuberculosis pleural effusion. Associated factors
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J.J. Soler*, V. Gil Suay, P. Cordero, M. Perpiñá, E. Martínez, J. Sanchis
Servicio de Neumología. Hospital Universitario La Fe. Valencia
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Nuestro objetivo ha sido determinar qué factores se relacionan con el desarrollo de engrosamiento pleural residual (EPR) al finalizar el tratamiento específico.

Se estudian 62 pacientes diagnosticados de tuberculosis pleural (TP), separados en 2 grupos en función de la presencia o ausencia de EPR > 2 mm en la porción lateral e inferior de una radiografía posteroanterior de tórax, al finalizar el tratamiento específico. Ningún paciente recibió corticoides. El 72,6% presentó engrosamiento, siendo este más frecuente entre los varones (odds ratio, 4,06; p = 0,034), y en los enfermos de edad media superior, 36 ± 21 frente a 27 ± 12 años (p = 0,05). El hábito tabáquico, tamaño del derrame, duración de la sintomatología, encapsulamiento, PPD, biopsia pleural, bacteriología y el pH, glucosa, proteínas y colesterol del líquido pleural, así como sus respectivos cocientes pleura/suero fueron similares en ambos grupos. La LDH pleural (LDHp) y su relación pleura/suero (LDHp/s) fue 454,3 ± 234,6 U/l y 3,21 ± 1,67 en el grupo con EPR, por 306,0 ± 137,2 U/l y 2,00 ± 1,16 del grupo sin secuelas (p = 0,004 y p = 0,016, respectivamente). Utilizando como punto de corte una LDH p/s superior a 2,10, la sensibilidad obtenida fue del 78,9% con especificidad del 71,4%, valor predictivo positivo del 88,2% y valor predictivo negativo del 55,5%.

Concluimos que: a) el EPR es una complicación frecuente; b) de predominio masculino; c) que guarda relación con la edad, y d) un valor superior a 2,10 en la relación LDH p/s puede predecir con aceptable seguridad la presencia de este trastorno.

Palabras clave:
Tuberculosis pleural
Engrosamiento pleural

We aimed to determine which factors were related to the development of residual pleural thickening (RPT) after completion of prescribed treatment.

Sixty-two patients with pleural tuberculosis (PTB) were assigned to 2 groups according to the presence or absence of RPT > 2 mm in the side and lower portion of a chest film after completion of prescribed treatment. No patient had been given corticoids. Thickening developed in 72.6%, more often in men (OR, 4.06; p = 0.034), in older patients (36 ± 21 versus 27 ± 12 years; p = 0.05). Smoking, size of effusion, duration of symptoms, encapsulation, PPD, pleural biopsy, bacteriology and pH, glucose, proteins and cholesterol in pleural fluids, as well as their respective pleura/serum coefficients, were similar in both groups. Pleural LDH (LDHp) and its pleura/serum coefficient (LDHp/LDHs) were 454.3 ± 234.6 U/l and 3.21 ± 1.67 U/l in the group with RPT and 306.0 ± 137.2 U/l and 2.00 ± 1.16 in the group with no sequelae (p = 0.004 and p = 0.016, respectively). Using 2.10 as the cutoff for LDHp/LDHs, sensitivity was 78.9% and specificity was 71.4%, giving a positive predictive value of 88.2% and a negative predictive value of 55.5%.

We conclude that RPT a) is a frequent complication, b) is mainly found in men, c) is age-related and d) can be fairly safely predicted using 2.10 as the cutoff for LDHp/LDHs.

Key words:
Pleural tuberculosis
Pleural thickening
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