array:23 [
  "pii" => "S0300289615322420"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)32242-0"
  "estado" => "S300"
  "fechaPublicacion" => "1984-07-01"
  "aid" => "72312"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
  "copyrightAnyo" => "1984"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 1984;20:164-8"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1877
    "formatos" => array:3 [
      "EPUB" => 55
      "HTML" => 724
      "PDF" => 1098
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615322432"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32243-2"
    "estado" => "S300"
    "fechaPublicacion" => "1984-07-01"
    "aid" => "72313"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1984;20:169-72"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1560
      "formatos" => array:3 [
        "EPUB" => 55
        "HTML" => 735
        "PDF" => 770
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Hemorragia masiva procedente de pleurotomia abierta en un empiema calcificado: tratamiento con ligadura intrapericardica de arteria y venas pulmonares"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "169"
          "paginaFinal" => "172"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Massive bleeding from an open pleurotomy in a calcified empyema: treatment by intrapericardial ligation of pulmonary artery and veins"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "F.A. De Linera, J.L. Cofiño, J.L. Naya, J. Rodriguez, F. Gosalbez"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "F.A."
              "apellidos" => "De Linera"
            ]
            1 => array:2 [
              "nombre" => "J.L."
              "apellidos" => "Cofiño"
            ]
            2 => array:2 [
              "nombre" => "J.L."
              "apellidos" => "Naya"
            ]
            3 => array:2 [
              "nombre" => "J."
              "apellidos" => "Rodriguez"
            ]
            4 => array:2 [
              "nombre" => "F."
              "apellidos" => "Gosalbez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615322432?idApp=UINPBA00003Z"
    "url" => "/03002896/0000002000000004/v1_201509151146/S0300289615322432/v1_201509151146/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0300289615322419"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32241-9"
    "estado" => "S300"
    "fechaPublicacion" => "1984-07-01"
    "aid" => "72311"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1984;20:160-3"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1416
      "formatos" => array:3 [
        "EPUB" => 74
        "HTML" => 563
        "PDF" => 779
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Tumores neurogenicos intratoracicos. Estudio de 23 casos"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "160"
          "paginaFinal" => "163"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Neurogenetic intrathoracic tumors. A report of 23 cases"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:2 [
        0 => array:2 [
          "autoresLista" => "E. Monso, R. Vidal, L.L. Joanmiquel, J. Morera"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "E."
              "apellidos" => "Monso"
            ]
            1 => array:2 [
              "nombre" => "R."
              "apellidos" => "Vidal"
            ]
            2 => array:2 [
              "nombre" => "L.L."
              "apellidos" => "Joanmiquel"
            ]
            3 => array:2 [
              "nombre" => "J."
              "apellidos" => "Morera"
            ]
          ]
        ]
        1 => array:2 [
          "autoresLista" => "J. Teixidor, L.L. Bernado, J. Astudillo"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "J."
              "apellidos" => "Teixidor"
            ]
            1 => array:2 [
              "nombre" => "L.L."
              "apellidos" => "Bernado"
            ]
            2 => array:2 [
              "nombre" => "J."
              "apellidos" => "Astudillo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615322419?idApp=UINPBA00003Z"
    "url" => "/03002896/0000002000000004/v1_201509151146/S0300289615322419/v1_201509151146/es/main.assets"
  ]
  "es" => array:13 [
    "idiomaDefecto" => true
    "titulo" => "Cancer de pulmon. Analisis de los hallazgos anatomopatologicos en cien casos de autopsias"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "164"
        "paginaFinal" => "168"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "M. Sole, J.A. Bombi, C. Llebaria, M. Cid, J. Villalta, A. Cardesa"
        "autores" => array:6 [
          0 => array:3 [
            "nombre" => "M."
            "apellidos" => "Sole"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "J&#46;A&#46;"
            "apellidos" => "Bombi"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "C&#46;"
            "apellidos" => "Llebaria"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "M&#46;"
            "apellidos" => "Cid"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;&#42;</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "J&#46;"
            "apellidos" => "Villalta"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;&#42;</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "Cardesa"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "Departamento de Anatom&#237;a Patol&#243;gica&#46; Facultad de Medicina y Hospital Cl&#237;nico y Provincial&#46; Universidad de Barcelona"
            "etiqueta" => "&#42;"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Medicina Interna&#46; Facultad de Medicina y Hospital Cl&#237;nico y Provincial&#46; Universidad de Barcelona"
            "etiqueta" => "&#42;&#42;"
            "identificador" => "aff0010"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Lung cancer&#46; Analysis of the pathological findings in 100 necropsy cases"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1983-11-15"
    "fechaAceptado" => "1984-03-03"
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se estudian los hallazgos de autopsia de 100 pacientes con c&#225;ncer de pulm&#243;n&#46; El c&#225;ncer del pulm&#243;n se hall&#243; en el 5&#44;8&#37; de los casos en nuestra serie de autopsias&#46; La relaci&#243;n varones&#58; mujeres fue de 8&#58;1&#46; El adenocarcinoma fue el tipo histol&#243;gico m&#225;s frecuente &#40;27&#37;&#41; seguido del carcinoma escamoso y el carcinoma indiferenciado de c&#233;lulas peque&#241;as&#44; con un 26&#37;&#46; Los restantes fueron carcinomas indiferenciados de c&#233;lulas grandes &#40;18&#37;&#41; y carcinomas mixtos &#40;3&#37;&#41;&#46; El 80&#37; de los adenocarcinomas eran de localizaci&#243;n perif&#233;rica&#44; y el 80&#37; de los carcinomas indiferenciados de c&#233;lulas peque&#241;as eran de localizaci&#243;n central&#46; El 82<span class="elsevierStyleItalic">&#37;</span> de los casos presentaron met&#225;stasis&#59; entre ellos&#44; todos los casos de carcinoma indiferenciado de c&#233;lulas peque&#241;as&#46; La localizaci&#243;n de las met&#225;stasis fueron&#58; ganglios linf&#225;ticos &#40;62&#37;&#41;&#44; suprarrenal &#40;37&#37;&#41;&#44; h&#237;gado &#40;36<span class="elsevierStyleItalic">&#37;&#41;</span>&#44; hueso &#40;28&#37;&#41; y SNC &#40;22&#37;&#41;&#44; principalmente&#46; Diecis&#233;is casos presentaban c&#225;ncer asociado &#40;seis carcinomas de pr&#243;stata&#44; tres de laringe&#44; dos de lengua&#44; principalmente&#41;&#46; En 30&#37; de los casos la causa de muerte fue una infecci&#243;n respiratoria&#46;</p></span>"
      ]
      "en" => array:1 [
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The necropsy findings in 100 patients with lung cancer are analyzed&#46; Lung cancer was found in 5&#46;8&#37; of cases in our autopsy series&#46; Male&#58; female ratio was 8&#58;1&#46; Adenocarcinoma was the most common histologicl type &#40;27&#37;&#41;&#44; followed by squamous carcinoma and small-cell non-differentiated carcinoma&#44; both with 26&#37;<span class="elsevierStyleItalic">&#46;</span> The remainder were large-cell non-differentiated carcinomas &#40;18&#37;&#41; and mixed carcinomas &#40;3&#37;&#41;&#46; 80<span class="elsevierStyleItalic">&#37;</span> of adenocarcinomas were periferally situated&#44; whereas 80&#37; of small-cell non-differentiated carcinomas were centrally situated&#46; 82&#37; of cases resulted in metastases&#59; among these&#44; all cases of small-cell non-differentiated carcinoma had metastases&#46; The localization of these was as follows&#58; lymph nodes &#40;62&#37;&#41;&#44; adrenal glands &#40;37&#37;&#41;&#44; liver &#40;36&#37;&#41;&#44; bone &#40;28&#37;&#41; and CNS &#40;22&#37;&#41;&#46; 16 cases had associated neoplasms &#40;6 had prosthatic carcinoma&#44; 3 had laryngeal carcinoma and 2 had tongue carcinoma&#44; among others&#41;&#46; In 30&#37; of cases the cause of death was respiratory tract infection&#46;</p></span>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:19 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Aspectos epidemiol&#243;gicos del carcinoma bronquial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46;M&#46; Monturiol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Hosp Gen"
                        "fecha" => "1976"
                        "volumen" => "16"
                        "paginaInicial" => "341"
                        "paginaFinal" => "352"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cancer mortality in Barcelona&#44; 1960-1978"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "F&#46;X&#46; Bosch"
                            1 => "J&#46; Orta"
                            2 => "A&#46; Garc&#237;a"
                            3 => "J&#46; Juvanet"
                            4 => "A&#46; Camprod&#243;n"
                            5 => "A&#46; Pumarola"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Epidem"
                        "fecha" => "1982"
                        "volumen" => "11"
                        "paginaInicial" => "46"
                        "paginaFinal" => "48"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Patolog&#237;a geogr&#225;fica del c&#225;ncer en Espa&#241;a"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "L&#46; Galindo"
                            1 => "F&#46; Algaba"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Patolog&#237;a"
                        "fecha" => "1981"
                        "numero" => "Supl"
                        "paginaInicial" => "17"
                        "paginaFinal" => "26"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pathology of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "H&#46; Spencer"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "edicion" => "Ed 3"
                        "fecha" => "1977"
                        "editorial" => "Pergamon Press"
                        "editorialLocalizacion" => "Oxford"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tumours in Iceland&#46; 7&#46; Malignant Epithelial tumours of the lung&#46; A histological classification&#44; epidemiol&#243;gica&#33; considerations and relation to smoking"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Hallgrimsson"
                            1 => "H&#46; Thorarisson"
                            2 => "H&#46; Tulinius"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acta Path Microbiol Immunol Scand&#44; Sect A"
                        "fecha" => "1983"
                        "volumen" => "91"
                        "paginaInicial" => "203"
                        "paginaFinal" => "207"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tumors of the lower respiratory tract"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "D&#46; Carter"
                            1 => "J&#46;C&#46; Eggleston"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Atlas of tumor pathology"
                        "fecha" => "1980"
                        "volumen" => "17"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The changing histopathology of lung c&#225;ncer&#46; A review of 1&#46;682 cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;G&#46; Vincent"
                            1 => "J&#46;W&#46; Picksen"
                            2 => "W&#46;W&#46; Lane"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "C&#225;ncer"
                        "fecha" => "1977"
                        "volumen" => "39"
                        "paginaInicial" => "1647"
                        "paginaFinal" => "1655"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/192433"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Neoplasias primitivas de pulm&#243;n Experiencia en material de autopsia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "F&#46; Alameda"
                            1 => "F&#46;J&#46; Sancho"
                            2 => "A&#46; Moreno"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Sant Pau"
                        "fecha" => "1983"
                        "volumen" => "4"
                        "paginaInicial" => "4"
                        "paginaFinal" => "6"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Datos epidemiol&#243;gicos en el carcinoma broncog&#233;nico &#40;II&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; L&#243;pez"
                            1 => "J&#46; Mart&#237;nez"
                            2 => "E&#46; P&#233;rez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barcelona&#41;"
                        "fecha" => "1979"
                        "volumen" => "72"
                        "paginaInicial" => "361"
                        "paginaFinal" => "368"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tumores malignos del aparato respiratorio"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46; Herrero"
                            1 => "M&#46;T&#46; Miralles"
                            2 => "A&#46; Fern&#225;ndez Ribas"
                            3 => "A&#46; Vi&#241;uelas"
                            4 => "A&#46; Santos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Patolog&#237;a"
                        "fecha" => "1981"
                        "numero" => "Supl"
                        "paginaInicial" => "51"
                        "paginaFinal" => "67"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Increasing incidence of adenocarcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Valaitis"
                            1 => "S&#46; Warren"
                            2 => "D&#46; Gamble"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1981"
                        "volumen" => "47"
                        "paginaInicial" => "1042"
                        "paginaFinal" => "1046"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6261919"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Metastatic carcinoma The lung as the site for the clinically undiagnosed primar"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;F&#46; Clary"
                            1 => "R&#46;P&#46; Michel"
                            2 => "N&#46;S&#46; Uberg"
                            3 => "R&#46;E&#46; Honson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "C&#225;ncer"
                        "fecha" => "1983"
                        "volumen" => "51"
                        "paginaInicial" => "362"
                        "paginaFinal" => "366"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6295600"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clasificaci&#243;n histol&#243;gica internacional de tumores N&#46;&#176; 1&#46; Tipos histol&#243;gicos de tumores pulmonares"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "L&#46; Kreyberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "OMS Ginebra"
                        "fecha" => "1967"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An&#225;lisis de una serie de 500 autopsias cl&#237;nicas&#58; II Diagn&#243;sticos principales"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;A&#46; Bombi"
                            1 => "C&#46; Llebaria"
                            2 => "A&#46; Rives"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barcelona&#41;"
                        "fecha" => "1981"
                        "volumen" => "77"
                        "paginaInicial" => "185"
                        "paginaFinal" => "189"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Scar cancer of the lung&#58; increase over a 21 year period"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "O&#46; Auerbach"
                            1 => "L&#46; Garfinkel"
                            2 => "V&#46;R&#46; Parks"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "C&#225;ncer"
                        "fecha" => "1979"
                        "volumen" => "43"
                        "paginaInicial" => "636"
                        "paginaFinal" => "642"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/217523"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Histologic typing of lung cancer in Louisiana"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "H&#46; Rothschild"
                            1 => "H&#46; Buechner"
                            2 => "R&#46; Welsh"
                            3 => "L&#46;J&#46; Vial"
                            4 => "R&#46; Weinberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "C&#225;ncer"
                        "fecha" => "1982"
                        "volumen" => "49"
                        "paginaInicial" => "1874"
                        "paginaFinal" => "1877"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6280847"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The Worid Health Organization histologycal typing of lung tumours Second edition"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "WHO"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Clin Pathol"
                        "fecha" => "1982"
                        "volumen" => "77"
                        "paginaInicial" => "123"
                        "paginaFinal" => "126"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7064914"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multiple primary malignant neoplasm 1&#46; Introduction and presentation of data"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "C&#46;G&#46; Moertel"
                            1 => "M&#46;B&#46; Dockerty"
                            2 => "A&#46;H&#46; Baggenstoss"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/1471-2407-14-221"
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1961"
                        "volumen" => "14"
                        "paginaInicial" => "221"
                        "paginaFinal" => "230"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24667084"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Two primary carcinomas of the lung&#58; adenocarcinoma and a metachronous squamous cell carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "B&#46; Coffman"
                            1 => "E&#46; Crum"
                            2 => "W&#46;B&#46; Forman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1983"
                        "volumen" => "51"
                        "paginaInicial" => "124"
                        "paginaFinal" => "126"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6336970"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000002000000004/v1_201509151146/S0300289615322420/v1_201509151146/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9277"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000002000000004/v1_201509151146/S0300289615322420/v1_201509151146/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615322420?idApp=UINPBA00003Z"
]
Share
Journal Information
Vol. 20. Issue 4.
Pages 164-168 (July - August 1984)
Share
Share
Download PDF
More article options
Vol. 20. Issue 4.
Pages 164-168 (July - August 1984)
Full text access
Cancer de pulmon. Analisis de los hallazgos anatomopatologicos en cien casos de autopsias
Lung cancer. Analysis of the pathological findings in 100 necropsy cases
Visits
4700
M. Sole*, J.A. Bombi*, C. Llebaria*, M. Cid**, J. Villalta**, A. Cardesa*
* Departamento de Anatomía Patológica. Facultad de Medicina y Hospital Clínico y Provincial. Universidad de Barcelona
** Servicio de Medicina Interna. Facultad de Medicina y Hospital Clínico y Provincial. Universidad de Barcelona
This item has received
Article information

Se estudian los hallazgos de autopsia de 100 pacientes con cáncer de pulmón. El cáncer del pulmón se halló en el 5,8% de los casos en nuestra serie de autopsias. La relación varones: mujeres fue de 8:1. El adenocarcinoma fue el tipo histológico más frecuente (27%) seguido del carcinoma escamoso y el carcinoma indiferenciado de células pequeñas, con un 26%. Los restantes fueron carcinomas indiferenciados de células grandes (18%) y carcinomas mixtos (3%). El 80% de los adenocarcinomas eran de localización periférica, y el 80% de los carcinomas indiferenciados de células pequeñas eran de localización central. El 82% de los casos presentaron metástasis; entre ellos, todos los casos de carcinoma indiferenciado de células pequeñas. La localización de las metástasis fueron: ganglios linfáticos (62%), suprarrenal (37%), hígado (36%), hueso (28%) y SNC (22%), principalmente. Dieciséis casos presentaban cáncer asociado (seis carcinomas de próstata, tres de laringe, dos de lengua, principalmente). En 30% de los casos la causa de muerte fue una infección respiratoria.

The necropsy findings in 100 patients with lung cancer are analyzed. Lung cancer was found in 5.8% of cases in our autopsy series. Male: female ratio was 8:1. Adenocarcinoma was the most common histologicl type (27%), followed by squamous carcinoma and small-cell non-differentiated carcinoma, both with 26%. The remainder were large-cell non-differentiated carcinomas (18%) and mixed carcinomas (3%). 80% of adenocarcinomas were periferally situated, whereas 80% of small-cell non-differentiated carcinomas were centrally situated. 82% of cases resulted in metastases; among these, all cases of small-cell non-differentiated carcinoma had metastases. The localization of these was as follows: lymph nodes (62%), adrenal glands (37%), liver (36%), bone (28%) and CNS (22%). 16 cases had associated neoplasms (6 had prosthatic carcinoma, 3 had laryngeal carcinoma and 2 had tongue carcinoma, among others). In 30% of cases the cause of death was respiratory tract infection.

Full text is only aviable in PDF
Bibliografia
[1.]
J.M. Monturiol.
Aspectos epidemiológicos del carcinoma bronquial.
Hosp Gen, 16 (1976), pp. 341-352
[2.]
F.X. Bosch, J. Orta, A. García, J. Juvanet, A. Camprodón, A. Pumarola.
Cancer mortality in Barcelona, 1960-1978.
Int J Epidem, 11 (1982), pp. 46-48
[3.]
L. Galindo, F. Algaba.
Patología geográfica del cáncer en España.
Patología, (1981), pp. 17-26
[4.]
H. Spencer.
Pathology of the lung.
Ed 3, Pergamon Press, (1977),
[5.]
J. Hallgrimsson, H. Thorarisson, H. Tulinius.
Tumours in Iceland. 7. Malignant Epithelial tumours of the lung. A histological classification, epidemiológica! considerations and relation to smoking.
Acta Path Microbiol Immunol Scand, Sect A, 91 (1983), pp. 203-207
[6.]
D. Carter, J.C. Eggleston.
Tumors of the lower respiratory tract.
Atlas of tumor pathology, 17 (1980),
[7.]
R.G. Vincent, J.W. Picksen, W.W. Lane.
The changing histopathology of lung cáncer. A review of 1.682 cases.
Cáncer, 39 (1977), pp. 1647-1655
[8.]
F. Alameda, F.J. Sancho, A. Moreno.
Neoplasias primitivas de pulmón Experiencia en material de autopsia.
Sant Pau, 4 (1983), pp. 4-6
[9.]
A. López, J. Martínez, E. Pérez.
Datos epidemiológicos en el carcinoma broncogénico (II).
Med Clin (Barcelona), 72 (1979), pp. 361-368
[10.]
A. Herrero, M.T. Miralles, A. Fernández Ribas, A. Viñuelas, A. Santos.
Tumores malignos del aparato respiratorio.
Patología, (1981), pp. 51-67
[11.]
J. Valaitis, S. Warren, D. Gamble.
Increasing incidence of adenocarcinoma of the lung.
Cancer, 47 (1981), pp. 1042-1046
[12.]
C.F. Clary, R.P. Michel, N.S. Uberg, R.E. Honson.
Metastatic carcinoma The lung as the site for the clinically undiagnosed primar.
Cáncer, 51 (1983), pp. 362-366
[13.]
L. Kreyberg.
Clasificación histológica internacional de tumores N.° 1. Tipos histológicos de tumores pulmonares.
OMS Ginebra, (1967),
[14.]
J.A. Bombi, C. Llebaria, A. Rives.
Análisis de una serie de 500 autopsias clínicas: II Diagnósticos principales.
Med Clin (Barcelona), 77 (1981), pp. 185-189
[15.]
O. Auerbach, L. Garfinkel, V.R. Parks.
Scar cancer of the lung: increase over a 21 year period.
Cáncer, 43 (1979), pp. 636-642
[16.]
H. Rothschild, H. Buechner, R. Welsh, L.J. Vial, R. Weinberg.
Histologic typing of lung cancer in Louisiana.
Cáncer, 49 (1982), pp. 1874-1877
[17.]
WHO.
The Worid Health Organization histologycal typing of lung tumours Second edition.
Am J Clin Pathol, 77 (1982), pp. 123-126
[18.]
C.G. Moertel, M.B. Dockerty, A.H. Baggenstoss.
Multiple primary malignant neoplasm 1. Introduction and presentation of data.
Cancer, 14 (1961), pp. 221-230
[19.]
B. Coffman, E. Crum, W.B. Forman.
Two primary carcinomas of the lung: adenocarcinoma and a metachronous squamous cell carcinoma.
Cancer, 51 (1983), pp. 124-126
Copyright © 1984. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?