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          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:42 [
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              "identificador" => "bib0005"
              "etiqueta" => "1."
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Occupational exposure to diisocyanates NIOSH criteria document for a recommended standard. Publication 78-215. Washington. DC, US Department of Health, Education and Welfare."
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Urethane polymers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "H. Ulrich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:6 [
                        "titulo" => "Kirk-Othmer: Encyclopedia of Chemical technology"
                        "fecha" => "1983"
                        "paginaInicial" => "507"
                        "paginaFinal" => "608"
                        "editorial" => "John Wiley & Sons Inc"
                        "editorialLocalizacion" => "New York"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Isocyanate in industry"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J.M. Buist"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Proc Roy Soc Med"
                        "fecha" => "1970"
                        "volumen" => "63"
                        "paginaInicial" => "365"
                        "paginaFinal" => "368"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5441965"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Respiratory hypersensitivity to diisocyanates"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R.J. Davies"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Clin Immunol Allergy"
                        "fecha" => "1984"
                        "volumen" => "4"
                        "paginaInicial" => "103"
                        "paginaFinal" => "123"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Documentation of the Threshold limit Value and biological exposure indices"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "ACGIH"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "edicion" => "5 ed"
                        "fecha" => "1986"
                        "editorial" => "Cincinnati"
                        "editorialLocalizacion" => "Ohio"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term effects on the health of men engaged in the manufacture of tolylene"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "W.G.F. Adams"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Ind Med"
                        "fecha" => "1975"
                        "volumen" => "32"
                        "paginaInicial" => "72"
                        "paginaFinal" => "78"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/164881"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Acute respiratory effects in workers exposed to low levels of TDI"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J.M. Peters"
                            1 => "R.L.H. Murphy"
                            2 => "L.D. Pagnato"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Environ Health"
                        "fecha" => "1986"
                        "volumen" => "16"
                        "paginaInicial" => "642"
                        "paginaFinal" => "647"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5652386"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Studies of isocyanate toxicity. Cumulative pulmonary effects in workers exposed to toluene diisocyanate"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J.M. Peters"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Proc Roy Soc Med"
                        "fecha" => "1970"
                        "volumen" => "63"
                        "paginaInicial" => "372"
                        "paginaFinal" => "375"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5441968"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Chronic pulmonary function loss from exposure to toluene diisocyanate"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "D.H. Wegman"
                            1 => "J.M. Peters"
                            2 => "L. Pagnotto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Br J Industr Med"
                        "fecha" => "1977"
                        "volumen" => "34"
                        "paginaInicial" => "196"
                        "paginaFinal" => "200"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Absence of respiratory effects in subjects exposed to low concentrations of TDI and MDI"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "A.W. Musk"
                            1 => "J.M. Peters"
                            2 => "L. DiBernardis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Occup Med"
                        "fecha" => "1982"
                        "volumen" => "24"
                        "paginaInicial" => "746"
                        "paginaFinal" => "750"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6292385"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A 10 year follow-up study of a group of workers exposed to isocyanates"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J.B. Gee"
                            1 => "W.K.C. Morgan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Occup Med"
                        "fecha" => "1985"
                        "volumen" => "27"
                        "paginaInicial" => "15"
                        "paginaFinal" => "18"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2982001"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Five year longitudinal study of workers employed in a new toluene diisocyanate manufactoring plant"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J.E. Diem"
                            1 => "R.N. Jones"
                            2 => "D.J. Hendrick"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/arrd.1982.126.3.420"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1982"
                        "volumen" => "126"
                        "paginaInicial" => "420"
                        "paginaFinal" => "428"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6289703"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Isocyanate and respiratory function: a study of workers producing polyurethane foam moulding"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "Q.T. Pham"
                            1 => "C. Cavelier"
                            2 => "P. Mereau"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Ann Occup Hyg"
                        "fecha" => "1978"
                        "volumen" => "21"
                        "paginaInicial" => "12"
                        "paginaFinal" => "129"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Etude clinique et experimentale sur quelques cas d’intoxication par les Desmour T (diisocyanate de Toluene 1-2-4 et 1-2-6)"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S. Fuch"
                            1 => "P. Valade"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arch Mal Prof Med Trav et Sec Soc"
                        "fecha" => "1951"
                        "volumen" => "12"
                        "paginaInicial" => "191"
                        "paginaFinal" => "196"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Isocyanate asthma: respiratory symptoms caused by disphenylmethane diisocianate"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A.R. Tansar"
                            1 => "M.P. Bourke"
                            2 => "A.G. Blandford"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "1973"
                        "volumen" => "28"
                        "paginaInicial" => "596"
                        "paginaFinal" => "600"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4784381"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16."
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Asthma caused by diphenylmethane diisocyanate in foundry workers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M. Zammit-Tabonga"
                            1 => "M. Sherkin"
                            2 => "K. Kijek"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/arrd.1983.128.2.226"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1983"
                        "volumen" => "128"
                        "paginaInicial" => "226"
                        "paginaFinal" => "230"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6881681"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Toluene diisocianate-induced asthma. Reaction to TDI, MDI, HDI and histamine"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "I.M. O’Brien"
                            1 => "M.G. Harries"
                            2 => "P.S. Burge"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Allergy"
                        "fecha" => "1979"
                        "volumen" => "9"
                        "paginaInicial" => "1"
                        "paginaFinal" => "6"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/217556"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Longuitudinal study of workers employed in the manufacture of toluene diisocyanate"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B.T. Butcher"
                            1 => "R.N. Jones"
                            2 => "C.E. O’Neil"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/arrd.1977.116.3.411"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1977"
                        "volumen" => "116"
                        "paginaInicial" => "411"
                        "paginaFinal" => "421"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/71003"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Occupational respiratory allergy: Epidemiologic and medicolegal aspects. Proceeding XII International Congress of Allergology and Clinical Immunology"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P. Gervais"
                            1 => "N. Rosenberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:5 [
                        "fecha" => "1986"
                        "paginaInicial" => "480"
                        "paginaFinal" => "485"
                        "editorial" => "Mosby Co"
                        "editorialLocalizacion" => "St. Louis"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Isocyanate-induced asthma: Review of 62 challenge tests"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J. Sastre"
                            1 => "D.E. Banks"
                            2 => "E. Ellis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1987"
                        "volumen" => "135"
                        "paginaInicial" => "256"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "21."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Long-term followup of workers with TDI asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "D.R. Moller"
                            1 => "R.T. McKay"
                            2 => "I.L. Bernstein"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1984"
                        "numero" => "suppl"
                        "paginaInicial" => "A159"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "22."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Follow-up study of patients with respiratory disease due to toluene diisocyanate (TDI)"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "P.L. Paggiaro"
                            1 => "A.M. Loi"
                            2 => "O. Rossi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Clin Allergy"
                        "fecha" => "1984"
                        "volumen" => "14"
                        "paginaInicial" => "462"
                        "paginaFinal" => "469"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "23."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Asma ocupacional por sustancias de bajo peso molecular"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J. Sastre"
                            1 => "M.D. Ibañez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Esp Alergol Inmunol Clin"
                        "fecha" => "1987"
                        "volumen" => "2"
                        "paginaInicial" => "391"
                        "paginaFinal" => "400"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "24."
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Stankus R, Sastre J, Salvaggio JE. Asthma induced by exposure to low molecular weight compounds and cigarette smoke. Current Pulmonol 1988 (en prensa)."
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "25."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Occupational asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M. Chang-Yeung"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1987"
                        "volumen" => "134"
                        "paginaInicial" => "686"
                        "paginaFinal" => "703"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "26."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fate of occupational asthma: a follow-up study of patients with occupational asthma due to western red cedar (Thuja plicata)"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M. Chang-Yeung"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/arrd.1977.116.6.1101"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1977"
                        "volumen" => "116"
                        "paginaInicial" => "1.023"
                        "paginaFinal" => "1.030"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/931183"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "27."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The in vitro effect of toluene diisocyanate on lymphocyte cyclic adenosine monophosphate production by isoproterenol, prostaglandin, and histamine"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "R.J. Davies"
                            1 => "B.T. Butcher"
                            2 => "C.E. O’Neil"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1977"
                        "volumen" => "60"
                        "paginaInicial" => "223"
                        "paginaFinal" => "229"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/198451"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "28."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Isocyanate-induced pulmonary diseases: a current perspective"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "I.L. Berstein"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1982"
                        "volumen" => "70"
                        "paginaInicial" => "24"
                        "paginaFinal" => "31"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6282949"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "29."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Longitudinal study of tolyl-reactive IgE antibodies in workers hypersensitivity to TDI"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "M.H. Karol"
                            1 => "T. Sanderg"
                            2 => "J. Riley"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Occup Med"
                        "fecha" => "1979"
                        "volumen" => "21"
                        "paginaInicial" => "354"
                        "paginaFinal" => "358"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/224155"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "30."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diverse profile of immunoreactivity in toluene diisocyanate asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J.S. Gallager"
                            1 => "C.S.T. Tse"
                            2 => "S.M. Brooks"
                            3 => "I.L. Berstein"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Occup Med"
                        "fecha" => "1981"
                        "volumen" => "23"
                        "paginaInicial" => "610"
                        "paginaFinal" => "613"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6268767"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "31."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Specific IgE antibodies in patients with isocyanate asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "V. Baur"
                            1 => "G. Fruhmann"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1981"
                        "volumen" => "80"
                        "paginaInicial" => "73"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6265152"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "32."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Toluene diisocyanate induced asthma: evaluation of antibodies in the serum of affected workers againts a tolyl monoisocyanate protein conjugate"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J.M. Danks"
                            1 => "O. Cromwell"
                            2 => "J.A. Buckingham"
                            3 => "A.J. Newman-Taylor"
                            4 => "R.J. Davies"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Allergy"
                        "fecha" => "1981"
                        "volumen" => "11"
                        "paginaInicial" => "161"
                        "paginaFinal" => "164"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6263516"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "33."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radioallergosorbent testing of toluene diisocyanate-reactive individuals using p-tolyl isocyanate antigen"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B.T. Butcher"
                            1 => "C.E. O’Neil"
                            2 => "M.A. Reed"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1980"
                        "volumen" => "66"
                        "paginaInicial" => "213"
                        "paginaFinal" => "216"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6251126"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "34."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evidence for carrier specificity of IgE antibodies detected by isocyanate protein conjugate in sera of isocyanate sensitivity individuals"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B.T. Butcher"
                            1 => "C. Mapp"
                            2 => "M.A. Reed"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1982"
                        "volumen" => "69"
                        "paginaInicial" => "123"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            34 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "35."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Inhalation challenge and pharmacologic studies of toluene diisocianate-sensitive workers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "B.T. Butcher"
                            1 => "R.N. Karr"
                            2 => "C.E. O’Neil"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1979"
                        "volumen" => "64"
                        "paginaInicial" => "146"
                        "paginaFinal" => "152"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/222827"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            35 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "36."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hypersensitivity pneumonitis after exposures to isocyanates"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:3 [
                            0 => "J. Charles"
                            1 => "A. Berstein"
                            2 => "B. Jones"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "1976"
                        "volumen" => "31"
                        "paginaInicial" => "127"
                        "paginaFinal" => "131"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/181861"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            36 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "37."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Serum neutrophil chemotactic activity of high molecular weight in. toluene diisocyante induced asthma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J. Sastre"
                            1 => "H.W. Barkman"
                            2 => "M. López"
                            3 => "D.E. Banks"
                            4 => "J.E. Salvaggio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1987"
                        "volumen" => "56"
                        "paginaInicial" => "1352"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            37 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "38."
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Immunologic release of neutrophil chemotactic activity from lung tissue"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "B.R.C. O’Briscol"
                            1 => "Th. Lee"
                            2 => "O. Cromwell"
                            3 => "A.B. Kay"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Allergy Clin Immunol"
                        "fecha" => "1983"
                        "volumen" => "72"
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                      "titulo" => "Considerations in the design and use of human inhalation challenge delivery Systems"
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                  ]
                  "host" => array:1 [
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                        "tituloSerie" => "Folia Allergol Immunol Clin"
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                            0 => "D.E. Banks"
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                    ]
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                        "tituloSerie" => "Ann Allergy"
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                        "paginaFinal" => "396"
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Vol. 24. Issue 6.
Pages 245-249 (November - December 1988)
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Vol. 24. Issue 6.
Pages 245-249 (November - December 1988)
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Asma inducido por isocianatos
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J. Sastre Domínguez, M.D. Ibáñez Sandín
Ex-Fellows, Allergy and Clinical Immunology Section, Department of Medicine. Tulane University School of Medicine New Orleans. USA
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Bibliografía
[1.]
Occupational exposure to diisocyanates NIOSH criteria document for a recommended standard. Publication 78-215. Washington. DC, US Department of Health, Education and Welfare.
[2.]
H. Ulrich.
Urethane polymers.
Kirk-Othmer: Encyclopedia of Chemical technology, John Wiley & Sons Inc, (1983), pp. 507-608
[3.]
J.M. Buist.
Isocyanate in industry.
Proc Roy Soc Med, 63 (1970), pp. 365-368
[4.]
R.J. Davies.
Respiratory hypersensitivity to diisocyanates.
Clin Immunol Allergy, 4 (1984), pp. 103-123
[5.]
ACGIH.
Documentation of the Threshold limit Value and biological exposure indices.
5 ed, Cincinnati, (1986),
[6.]
W.G.F. Adams.
Long-term effects on the health of men engaged in the manufacture of tolylene.
Br J Ind Med, 32 (1975), pp. 72-78
[7.]
J.M. Peters, R.L.H. Murphy, L.D. Pagnato, et al.
Acute respiratory effects in workers exposed to low levels of TDI.
Arch Environ Health, 16 (1986), pp. 642-647
[8.]
J.M. Peters.
Studies of isocyanate toxicity. Cumulative pulmonary effects in workers exposed to toluene diisocyanate.
Proc Roy Soc Med, 63 (1970), pp. 372-375
[9.]
D.H. Wegman, J.M. Peters, L. Pagnotto, et al.
Chronic pulmonary function loss from exposure to toluene diisocyanate.
Br J Industr Med, 34 (1977), pp. 196-200
[10.]
A.W. Musk, J.M. Peters, L. DiBernardis, et al.
Absence of respiratory effects in subjects exposed to low concentrations of TDI and MDI.
J Occup Med, 24 (1982), pp. 746-750
[11.]
J.B. Gee, W.K.C. Morgan.
A 10 year follow-up study of a group of workers exposed to isocyanates.
J Occup Med, 27 (1985), pp. 15-18
[12.]
J.E. Diem, R.N. Jones, D.J. Hendrick, et al.
Five year longitudinal study of workers employed in a new toluene diisocyanate manufactoring plant.
Am Rev Respir Dis, 126 (1982), pp. 420-428
[13.]
Q.T. Pham, C. Cavelier, P. Mereau, et al.
Isocyanate and respiratory function: a study of workers producing polyurethane foam moulding.
Ann Occup Hyg, 21 (1978), pp. 12-129
[14.]
S. Fuch, P. Valade.
Etude clinique et experimentale sur quelques cas d’intoxication par les Desmour T (diisocyanate de Toluene 1-2-4 et 1-2-6).
Arch Mal Prof Med Trav et Sec Soc, 12 (1951), pp. 191-196
[15.]
A.R. Tansar, M.P. Bourke, A.G. Blandford.
Isocyanate asthma: respiratory symptoms caused by disphenylmethane diisocianate.
Thorax, 28 (1973), pp. 596-600
[16.]
M. Zammit-Tabonga, M. Sherkin, K. Kijek, et al.
Asthma caused by diphenylmethane diisocyanate in foundry workers.
Am Rev Respir Dis, 128 (1983), pp. 226-230
[17.]
I.M. O’Brien, M.G. Harries, P.S. Burge, et al.
Toluene diisocianate-induced asthma. Reaction to TDI, MDI, HDI and histamine.
Clin Allergy, 9 (1979), pp. 1-6
[18.]
B.T. Butcher, R.N. Jones, C.E. O’Neil, et al.
Longuitudinal study of workers employed in the manufacture of toluene diisocyanate.
Am Rev Respir Dis, 116 (1977), pp. 411-421
[19.]
P. Gervais, N. Rosenberg.
Occupational respiratory allergy: Epidemiologic and medicolegal aspects. Proceeding XII International Congress of Allergology and Clinical Immunology.
Mosby Co, (1986), pp. 480-485
[20.]
J. Sastre, D.E. Banks, E. Ellis, et al.
Isocyanate-induced asthma: Review of 62 challenge tests.
Am Rev Respir Dis, 135 (1987), pp. 256
[21.]
D.R. Moller, R.T. McKay, I.L. Bernstein, et al.
Long-term followup of workers with TDI asthma.
Am Rev Respir Dis, (1984), pp. A159
[22.]
P.L. Paggiaro, A.M. Loi, O. Rossi, et al.
Follow-up study of patients with respiratory disease due to toluene diisocyanate (TDI).
Clin Allergy, 14 (1984), pp. 462-469
[23.]
J. Sastre, M.D. Ibañez.
Asma ocupacional por sustancias de bajo peso molecular.
Rev Esp Alergol Inmunol Clin, 2 (1987), pp. 391-400
[24.]
Stankus R, Sastre J, Salvaggio JE. Asthma induced by exposure to low molecular weight compounds and cigarette smoke. Current Pulmonol 1988 (en prensa).
[25.]
M. Chang-Yeung.
Occupational asthma.
Am Rev Respir Dis, 134 (1987), pp. 686-703
[26.]
M. Chang-Yeung.
Fate of occupational asthma: a follow-up study of patients with occupational asthma due to western red cedar (Thuja plicata).
Am Rev Respir Dis, 116 (1977), pp. 1.023-1.030
[27.]
R.J. Davies, B.T. Butcher, C.E. O’Neil, et al.
The in vitro effect of toluene diisocyanate on lymphocyte cyclic adenosine monophosphate production by isoproterenol, prostaglandin, and histamine.
J Allergy Clin Immunol, 60 (1977), pp. 223-229
[28.]
I.L. Berstein.
Isocyanate-induced pulmonary diseases: a current perspective.
J Allergy Clin Immunol, 70 (1982), pp. 24-31
[29.]
M.H. Karol, T. Sanderg, J. Riley, et al.
Longitudinal study of tolyl-reactive IgE antibodies in workers hypersensitivity to TDI.
J Occup Med, 21 (1979), pp. 354-358
[30.]
J.S. Gallager, C.S.T. Tse, S.M. Brooks, I.L. Berstein.
Diverse profile of immunoreactivity in toluene diisocyanate asthma.
J Occup Med, 23 (1981), pp. 610-613
[31.]
V. Baur, G. Fruhmann.
Specific IgE antibodies in patients with isocyanate asthma.
Chest, 80 (1981), pp. 73
[32.]
J.M. Danks, O. Cromwell, J.A. Buckingham, A.J. Newman-Taylor, R.J. Davies.
Toluene diisocyanate induced asthma: evaluation of antibodies in the serum of affected workers againts a tolyl monoisocyanate protein conjugate.
Clin Allergy, 11 (1981), pp. 161-164
[33.]
B.T. Butcher, C.E. O’Neil, M.A. Reed, et al.
Radioallergosorbent testing of toluene diisocyanate-reactive individuals using p-tolyl isocyanate antigen.
J Allergy Clin Immunol, 66 (1980), pp. 213-216
[34.]
B.T. Butcher, C. Mapp, M.A. Reed, et al.
Evidence for carrier specificity of IgE antibodies detected by isocyanate protein conjugate in sera of isocyanate sensitivity individuals.
J Allergy Clin Immunol, 69 (1982), pp. 123
[35.]
B.T. Butcher, R.N. Karr, C.E. O’Neil, et al.
Inhalation challenge and pharmacologic studies of toluene diisocianate-sensitive workers.
J Allergy Clin Immunol, 64 (1979), pp. 146-152
[36.]
J. Charles, A. Berstein, B. Jones, et al.
Hypersensitivity pneumonitis after exposures to isocyanates.
Thorax, 31 (1976), pp. 127-131
[37.]
J. Sastre, H.W. Barkman, M. López, D.E. Banks, J.E. Salvaggio.
Serum neutrophil chemotactic activity of high molecular weight in. toluene diisocyante induced asthma.
Am Rev Respir Dis, 56 (1987), pp. 1352
[38.]
B.R.C. O’Briscol, Th. Lee, O. Cromwell, A.B. Kay.
Immunologic release of neutrophil chemotactic activity from lung tissue.
J Allergy Clin Immunol, 72 (1983), pp. 695-701
[39.]
C. Mapp, G.R. DiGiacomo, L. Zedda, et al.
Isocyanate-induced asthma: Review of 165 cases studied in 1983-85.
J Allergy Clin Immunol, 77 (1986), pp. 173
[40.]
Y.Y. Hammad, R.J. Rando, H. Abdel-Kader.
Considerations in the design and use of human inhalation challenge delivery Systems.
Folia Allergol Immunol Clin, 32 (1985), pp. 37-44
[41.]
D.E. Banks, B.T. Butcher, J.E. Salvaggio.
Isocyanate-induced respiratory disease.
Ann Allergy, 57 (1987), pp. 389-396
[42.]
L.M. Fabbri, P. Chiesura-Corona, L. DelVecchio, et al.
Prednisone inhibits late asthmatic reaction and associated increase in airways responsiveness induced by TDI sensitized subjects.
Am Rev Respir Dis, 132 (1985), pp. 1.010-1.014
Copyright © 1988. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
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