array:22 [ "pii" => "S0300289624002862" "issn" => "03002896" "doi" => "10.1016/j.arbres.2024.07.021" "estado" => "S300" "fechaPublicacion" => "2024-11-01" "aid" => "3637" "copyright" => "SEPAR" "copyrightAnyo" => "2024" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2024;60:731-2" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "itemAnterior" => array:18 [ "pii" => "S030028962400276X" "issn" => "03002896" "doi" => "10.1016/j.arbres.2024.07.014" "estado" => "S300" "fechaPublicacion" => "2024-11-01" "aid" => "3630" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2024;60:729-30" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Pulmonary <span class="elsevierStyleItalic">Tropheryma whipplei</span> Infection Diagnosed by Metagenomic Next-generation Sequencing: A Case Report" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "729" "paginaFinal" => "730" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 841 "Ancho" => 1476 "Tamanyo" => 218748 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Gastroscopy revealed the presence of multiple ulcers at the gastric angle (A). Colonoscopy showed a polyp in the sigmoid colon (B). Chest CT images revealed pulmonary nodules (yellow arrow) and patchy opacities (blue arrow) in the apical segment of the right upper lobe (C and D). Fiberoptic bronchoscopy with no notable abnormalities (E). Chest CT 3 months after treatment with doxycycline (F and G).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Xiaoting Zhou, Chuanjun Huang, Jianfeng Zhang" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Xiaoting" "apellidos" => "Zhou" ] 1 => array:2 [ "nombre" => "Chuanjun" "apellidos" => "Huang" ] 2 => array:2 [ "nombre" => "Jianfeng" "apellidos" => "Zhang" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028962400276X?idApp=UINPBA00003Z" "url" => "/03002896/0000006000000011/v1_202411050534/S030028962400276X/v1_202411050534/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Acute Fibrinous and Organizing Pneumonia Associated With <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span>" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "731" "paginaFinal" => "732" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "David Luengo Gómez, Dámaris Romeral-Navarro, Ester Fátima Sánchez Álvarez" "autores" => array:3 [ 0 => array:3 [ "nombre" => "David" "apellidos" => "Luengo Gómez" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 1 => array:4 [ "nombre" => "Dámaris" "apellidos" => "Romeral-Navarro" "email" => array:1 [ 0 => "damaris.romeral@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 2 => array:3 [ "nombre" => "Ester Fátima" "apellidos" => "Sánchez Álvarez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Radiology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Pneumology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2151 "Ancho" => 4100 "Tamanyo" => 1720299 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Chest computed tomography at admission (A) and a few days later (B) with coronal reconstruction with maximum intensity projection (C), demonstrating volume loss of the right upper lobe and atelectasis, patchy centrilobular nodules of irregular morphology and peribronchovascular distribution (more evident in C). Detail of “fibrin ball” occupying alveolar space (hematoxylin and eosin, ×10) (D). CD68+ staining in epithelioid histiocytes (E). Masson's trichrome staining shows fibrin clusters (F).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 75-year-old woman presented with dyspnea and acute respiratory failure (oxygen saturation 89%). A computed tomography (CT) scan was performed (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A–C), and the differential diagnosis included tuberculosis reactivation and atypical pneumonia. The patient was initiated on empiric treatment with meropenem and systemic corticosteroids. The interferon-gamma release assay for <span class="elsevierStyleItalic">Mycobacterium tuberculosis</span> was positive, and the acid-fast bacilli (AFB) smear microscopy was negative. Despite the addition of linezolid and weight-adjusted antituberculosis therapy, the patient's condition continued to deteriorate, necessitating the postponement of a planned bronchoscopy with bronchoalveolar lavage. The patient ultimately succumbed 15 days after admission. A postmortem CT-guided biopsy revealed acute fibrinous and organizing pneumonia (AFOP) (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>D–F). The microbiological results demonstrated a positive polymerase chain reaction (PCR) for the <span class="elsevierStyleItalic">M. tuberculosis</span> complex.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">AFOP is a rare interstitial pneumonia characterized by the presence of fibrin “balls” within alveolar spaces, with a mortality rate of 50%. In contrast to diffuse alveolar damage, AFOP is characterized by the absence of hyaline membranes and a more irregular and less extensive distribution of fibrin. The clinical presentation is non-specific, typically acute or subacute, and the known causes include drugs, hypersensitivity pneumonitis, collagen disease, infections, and idiopathic cases.<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">1,2</span></a><span class="elsevierStyleItalic">M. tuberculosis</span> is a rare cause of this condition.<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">2,3</span></a> This case shares key aspects with that of Zhao X et al.,<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a> including rapid deterioration with progression of pulmonary lesions and the need for biopsy for definitive diagnosis. It emphasizes the importance of postmortem examinations, including histopathologic and microbiologic analyses, in clarifying ambiguous clinical conditions.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0015" class="elsevierStylePara elsevierViewall">This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of interest</span><p id="par0020" class="elsevierStylePara elsevierViewall">The authors declare not to have any conflicts of interest that may be considered to influence directly or indirectly the content of the manuscript.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Artificial intelligence involvement</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors declare that no artificial intelligence was used in the preparation of this manuscript.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:4 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of interest" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Artificial intelligence involvement" ] 3 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2151 "Ancho" => 4100 "Tamanyo" => 1720299 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Chest computed tomography at admission (A) and a few days later (B) with coronal reconstruction with maximum intensity projection (C), demonstrating volume loss of the right upper lobe and atelectasis, patchy centrilobular nodules of irregular morphology and peribronchovascular distribution (more evident in C). Detail of “fibrin ball” occupying alveolar space (hematoxylin and eosin, ×10) (D). CD68+ staining in epithelioid histiocytes (E). Masson's trichrome staining shows fibrin clusters (F).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0020" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute fibrinous and organizing pneumonia: a histological pattern of lung injury and possible variant of diffuse alveolar damage" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M.B. Beasley" 1 => "T.J. Franks" 2 => "J.R. Galvin" 3 => "B. Gochuico" 4 => "W.D. Travis" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.5858/2002-126-1064-AFAOP" "Revista" => array:7 [ "tituloSerie" => "Arch Pathol Lab Med" "fecha" => "2002" "volumen" => "126" "numero" => "9" "paginaInicial" => "1064" "paginaFinal" => "1070" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12204055" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0025" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnostic problems related to acute fibrinous and organizing pneumonia: misdiagnosis in 2 cases of lung consolidation and occupying lesions" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A.N. Feng" 1 => "H.R. Cai" 2 => "Q. Zhou" 3 => "Y.F. Zhang" 4 => "F.Q. Meng" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Clin Exp Pathol" "fecha" => "2014" "volumen" => "7" "numero" => "7" "paginaInicial" => "4493" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25120840" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0030" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary tuberculosis associated acute fibrinous and organizing pneumonia: a case report and literature review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "X. Zhao" 1 => "Y. Cheng" 2 => "Y. Xiong" 3 => "G. Wang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/CRJ.13626" "Revista" => array:6 [ "tituloSerie" => "Clin Respir J" "fecha" => "2023" "volumen" => "17" "numero" => "6" "paginaInicial" => "499" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/37156734" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/03002896/0000006000000011/v1_202411050534/S0300289624002862/v1_202411050534/en/main.assets" "Apartado" => array:4 [ "identificador" => "98298" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Cllinical Images" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000006000000011/v1_202411050534/S0300289624002862/v1_202411050534/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289624002862?idApp=UINPBA00003Z" ]
Journal Information
Vol. 60. Issue 11.
Pages 731-732 (November 2024)
Vol. 60. Issue 11.
Pages 731-732 (November 2024)
Clinical Image
Acute Fibrinous and Organizing Pneumonia Associated With Mycobacterium tuberculosis
Visits
634
This item has received
Article information
These are the options to access the full texts of the publication Archivos de Bronconeumología