Journal Information
Vol. 36. Issue 10.
Pages 574-579 (November 2000)
Share
Share
Download PDF
More article options
Vol. 36. Issue 10.
Pages 574-579 (November 2000)
Full text access
Papel de la vía aérea superior en la patogenia del síndrome de apneas obstructivas del sueño
Visits
8801
M. Carrera, F. Barbé, A.G.N. Agustí
Corresponding author
aagusti@hsd.es

Correspondencia: Servicio de Neumología. Hospital Universitario Son Dureta. Andrea Doria, 55. 07014 Palma de Mallorca.
Servicio de Neumología. Hospital Universitario Son Dureta. Palma de Mallorca
This item has received
Article information
Full text is only aviable in PDF
Bibliografía
[1.]
D.W. Hudgel.
Mechanisms of obstructive sleep apnea.
Chest, 101 (1992), pp. 541-549
[2.]
D.W. Hudgel, R.J. Martin, B. Johnson, P. Hill.
Mechanics of the respiratory system and breathing pattern during sleep in normal humans.
J Appl Physiol, 56 (1984), pp. 133-137
[3.]
L. Wiegand, C. Zwillich, D.P. White.
Collapsibility of the human upper airway during normal sleep.
J Appl Physiol, 66 (1989), pp. 1800-1809
[4.]
E. Sforza, C. Petiau, T. Weiss, A. Thibault, J. Krieger.
Pharyngeal critical pressure in patients with obstructive sleep apnea syndrome Clinical implications.
Am J Respir Crit Care Med, 159 (1999), pp. 149-157
[5.]
S.T. Pendlebury, J.L. Pepin, D. Veale, P. Levy.
Natural evolution of moderate sleep apnoea syndrome: significant progression over a mean of 17 months.
Thorax, 52 (1997), pp. 872-878
[6.]
D. Friberg, T. Ansved, K. Borg, B. Carlson-Nordlander, H. Larsson, E. Svanborg.
Histological indications of a progresive snorers disease in an upper airway muscle.
Am J Respir Crit Care Med, 157 (1998), pp. 586-593
[7.]
K.E. Shelton, S.B. Gay, D.E. Hollowell, H. Woodson, P.M. Suratt.
Mandible enclosure of upper airway and weight in obstructive sleep apnea.
Am Rev Respir Dis, 148 (1993), pp. 195-200
[8.]
R.L. Horner, R.H. Mohiaddin, D.G. Lowell, S.A. Shea, E.D. Burman, D.B. Longmore, et al.
Sites and sizes of fat deposits around the pharynx in obese patients with obstructive sleep apnoea and weight matched controls.
Eur Respir J, 2 (1989), pp. 613-622
[9.]
T.D. Bradley, I.G. Brown, R.F. Gossman, N. Zamel, D. Martinez, E.A. Phillipson, et al.
Pharyngeal size in snorers, nonsnorers, and patients with obstructive sleep apnea.
N Engl J Med, 315 (1986), pp. 1327-1331
[10.]
K.E. Shelton, H. Woodson, S. Gay, P.M. Suratt.
Pharyngeal fat in obstructive sleep apnea.
Am Rev Respir Dis, 148 (1993), pp. 462-466
[11.]
I. Katz, J. Stradling, A.S. Slutsky, N. Zamel, V. Hoffstein.
Do patients with obstructive sleep apnea have thick necks?.
Am Rev Respir Dis, 141 (1990), pp. 1228-1231
[12.]
R.J. Davies, J.R. Stradling.
The relationship between neck circumference, radiographic pharyngeal anatomy, and the obstructive sleep apnoea syndrome.
Eur Respir J, 3 (1990), pp. 509-514
[13.]
J.L. Stauffer, M.K. Buick, E.O. Bixler, F.E. Sharkey, A.B. Abt, E.K. Manders, et al.
Morphology of the uvula in obstructive sleep apnea.
Am Rev Respir Dis, 140 (1989), pp. 724-728
[14.]
I.L. Mortimore, I. Marshall, P.K. Wraith, R.J. Sellar, N.J. Douglas.
Neck and total body fat deposition in nonobese and obese patients with sleep apnea compared with that in control subjects.
Am J Respir Crit Care Med, 157 (1998), pp. 280-283
[15.]
R.R. Grunstein, I. Wilcox.
Sleep-disordered breathing and obesity.
Bailliere's Clinical Endocrinology, 8 (1994), pp. 601-628
[16.]
I.T. Whittle, I. Marshall, I.L. Mortimore, P.K. Wraith, R.J. Sellar, N.J. Douglas.
Neck soft tissue and fat distribution: comparison between normal men and women by magnetic resonance imaging.
Thorax, 54 (1999), pp. 323-328
[17.]
J.S. Koenig, B. Thach.
Effects of mass loading on the upper airway.
J Appl Physiol, 64 (1998), pp. 2294-2299
[18.]
D.O. Rodenstein, G. Dooms, Y. Thomas, G. Liistro, D.C. Stanescu, C. Culée, et al.
Pharyngeal shape and dimensions in healthy subjects, snorers and patients with obstructive sleep apnoea.
Thorax, 45 (1990), pp. 722-727
[19.]
J.C. Leiter.
Upper airway shape. Is it important in the pahogenesis of obstructive sleep apnea?.
Am J Respir Crit Care Med, 153 (1996), pp. 894-898
[20.]
R. Jokic, A. Klimaszewski, J. Mink, F. Fitzpatrick.
Surface tension forces in sleep apnea: the role of a soft tissue lubricant.
Am J Respir Crit Care Med, 157 (1998), pp. 1522-1525
[21.]
J.R. Wheatley, D.P. White.
The influence of sleep on pharyngeal reflexes.
Sleep, 16 (1993), pp. S87-S89
[22.]
P.C. Deegan, E. Mulloy, W.T. McNicholas.
Topical oropharyngeal anesthesia in patients with obstructive sleep apnea.
Am J Respir Crit Care Med, 151 (1995), pp. 1108-1112
[23.]
D. Friberg, B. Gazelius, T. Hokfelt, B. Nordlander.
Abnormal afferent nerve endings in the soft palatal mucosa of sleep apneics and habitual snorers.
Regul Pept, 71 (1997), pp. 29-36
[24.]
J.A. Rowley, B.R. Zahn, M.A. Babcock, M. Badr.
The effect of rapid eye movement (REM) sleep on upper airway mechanics in normal human subjects.
J Physiol (London), 510 (1998), pp. 963-976
[25.]
J. Krieger.
Breathing during sleep in normal subjects.
Principles and practice of sleep medicine, 2.ª ed, pp. 212-223
[26.]
J.A. Dempsey, C.A. Smith, C.A. Harms, C. Chow, K.W. Saupe.
Sleepinduced breathing instability.
Sleep, 19 (1996), pp. 236-247
[27.]
M.H. Chase, F.R. Morales.
The control of motoneurons during sleep.
Principles and practice of sleep medicine, 2.ª ed, pp. 163-175
[28.]
J.M. Lopes, E. Tabachnik, N.L. Muller.
Total airway resistance and respiratory muscle activity during sleep.
J Appl Physiol, 54 (1983), pp. 773-777
[29.]
R.B. Berry, K. Gleeson.
Respiratory arousal from sleep: mechanisms and significance.
Sleep, 20 (1997), pp. 654-675
[30.]
K.G. Henke, M.S. Badr, J.B. Skatrud, J.A. Dempsey.
Load compensation and respiratory muscle function during sleep.
J Appl Physiol, 72 (1992), pp. 1221-1234
[31.]
J.A. Block, J.A. Faulkner, R.L. Hughes, J.E. Remmers, B. Thach.
Factors influencing upper airway closure.
Chest, 86 (1984), pp. 114-122
[32.]
H. Kimura, M. Niijima, H. Edo, K. Tatsumi, Y. Honda, T. Kuriyama.
The effect of hypoxic depression on genioglossal muscle activity in healthy subjects and obstructive sleep apnea patients.
Sleep, 16 (1993), pp. S135-S136
[33.]
V.K. Somers, F.M. Abboud.
Chemoreflexes-responses, interactions and implications for sleep apnea.
Sleep, 16 (1990), pp. S30-S34
[34.]
S. Isono, J.E. Remmers.
Anatomy and physiology of upper airway obstruction.
Principles and practice of sleep medicine, 2.ª ed, pp. 642-656
[35.]
I.L. Mortimore, N.J. Douglas.
Palatal muscle EMG response to negative pressure in awake sleep apneic and control subjects.
Am J Respir Crit Care Med, 156 (1997), pp. 867-873
[36.]
R.L. Horner, A. Innes, A. Guz.
Reflex pharyngeal dilator muscle activation by stimuli of negative airway pressure in awake man.
Sleep, 16 (1993), pp. S85-S86
[37.]
O.P. Mathew.
Upper airway negative-presure effects on respiratory activity of upper airway muscles.
J Appl Physiol, 56 (1984), pp. 500-505
[38.]
E. Van Lunteren, K.P. Strohl.
The muscles of the upper airway.
Clin Chest Med, 7 (1986), pp. 171-181
[39.]
E. Van Lunteren.
Upper-airway effects on breathing.
The lung: scientific foundations, pp. 1631-1643
[40.]
D.W. Hudgel.
The role of upper airway anatomy and physiology in obstructive sleep apnea.
Clin Chest Med, 13 (1992), pp. 383-398
[41.]
D.J. Tangel, W.S. Mezzanotte, D.P. White.
The influence of sleep on tensor palatini EMG and upper airway resistance in normal subjects.
J Appl Physiol, 70 (1991), pp. 2574-2581
[42.]
J.B. Skatrud, J.A. Dempsey.
Airway resistance and respiratory muscle function in snorers during NREM sleep.
J Appl Physiol, 59 (1985), pp. 328-335
[43.]
J.R. Wheatley, W.S. Mezzanotte, D.J. Tangel, D.P. White.
Influence of sleep on genioglossus muscle activation by negative pressure in normal men.
Am Rev Respir Dis, 148 (1993), pp. 597-605
[44.]
W.S. Mezzanotte, D.J. Tangel, D.P. White.
Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism).
J Clin Invest, 89 (1992), pp. 1571-1579
[45.]
N.J. Douglas, O. Polo.
Pathogenesis of obstructive sleep apnoea/hypopnoea syndrome.
Lancet, 344 (1994), pp. 653-655
[46.]
J.E. Remmers, W.J. DeGroot, E.K. Sauerland, A.M. Anch.
Pathogenesis of upper airway occlusion during sleep.
J Appl Physiol, 44 (1978), pp. 931-938
[47.]
J.C. Hendricks, B.J. Petrof, K. Panckeri, A.I. Pack.
Upper airway dilating muscle hyperactivity during non-rapid eye movement sleep in English bulldogs.
Am Rev Respir Dis, 148 (1993), pp. 185-194
[48.]
B.J. Petrof, J.C. Hendricks, A.I. Pack.
Does Upper airway muscle injury trigger a vicious cycle in obstructive sleep apnea?. A hypothesis.
Sleep, 19 (1996), pp. 465-471
[49.]
L. Ferini-Strambi, S. Smirne, H. Moz, B. Sferrazza, S. Iannaccone.
Muscle fibre type and obstructive sleep apnea.
Sleep Online, 1 (1998), pp. 24-27
[50.]
F. Sériès, J.A. Simoneau, S. St Pierre, I. Marc.
Characteristics of the genioglossus and musculus uvulae in sleep apnea hypopnea syndrome and in snorers.
Am J Respir Crit Care Med, 153 (1996), pp. 1870-1874
[51.]
F. Sériès, C. Côté, J.-A. Simoneau, Y. Gélinas, S. St. Pierre, J. Leclerc, et al.
Physiologic, metabolic, and muscle fiber type characteristics of musculus uvulae in sleep apnea hypopnea syndrome and in snorers.
J Clin Invest, 95 (1995), pp. 20-25
[52.]
C. Guilleminault, R. Stoohs, S. Duncan.
Snoring (I) Daytime sleepiness in regular heavy snorers.
Chest, 99 (1991), pp. 40-48
[53.]
M. Carrera, F. Barbé, J. Sauleda, M. Tomás, C. Gómez, A.G.N. Agustí.
Patients with obstructive sleep apnea exhibit genioglossus dysfunction that is normalized after treatment with continuous positive airway pressure.
Am J Respir Crit Care Med, 159 (1999), pp. 1960-1966
[54.]
P.M. Suratt, R.F. Mctier, S.C. Wilhoit.
Upper airway muscle activation. is augmented in patients with obstructive sleep apnea compared to that in normal subjects.
Am Rev Respir Dis, 137 (1988), pp. 889-894
[55.]
R. Mathur, N.J. Douglas.
Family studies in patients with the sleep apnea-hypopnea syndrome.
Ann Intern Med, 122 (1995), pp. 174-178
[56.]
S. Redline, P.V. Tishler.
Familial influences on sleep apnea.
2.ª ed., pp. 363-378
[57.]
S. Redline, P.V. Tishier, T.D. Tosteson, J. Williamson, K. Kump, I. Browner, et al.
The familial aggregation of obstructive sleep apnea.
Am J Respir Crit Care Med, 151 (1995), pp. 682-687
[58.]
R.J. Schwab.
Sex differences and sleep apnoea.
Thorax, 54 (1999), pp. 284-285
[59.]
C. Bouchard, J.P. Després, P. Mauriège.
Genetic and nongenetic determinants of regional fat distribution.
Endocrine Rev, 14 (1999), pp. 72-93
[60.]
K.P. Strohl.
Tumor necrosis factor and sleep apnea.
Am J Respir Crit Care Med, 153 (1996), pp. 893
[61.]
A.G.N. Agustí, F. Barbé, B. Togores.
Exhaled nitric oxide in patients with sleep apnea.
Sleep, 22 (1999), pp. 231-235
[62.]
M.R. Dzoljic, R. De Vries, R. Van Leeuwen.
Sleep and nitric oxide: effects of 7-nitro indazole, inhibitor of brain nitric oxide synthase.
Brain Res, 718 (1996), pp. 145-150
[63.]
C.P. O’Donnell, C.D. Schaub, A.S. Haines, D.E. Berkowitz, C.G. Tankersley, A.R. Schwartz, et al.
Leptin prevents respiratory depression in obesity.
Am J Respir Crit Care Med, 159 (1999), pp. 1477-1484
[64.]
P. Entzian, K. Linnemann, M. Schlaak, P. Zabel.
Obstructive sleep apnea syndrome and circadian rhythms of hormones and cytokines.
Am J Respir Crit Care Med, 153 (1996), pp. 1080-1086
[65.]
D.W. Hudgel, S. Thanakitcharu.
Pharmacologic treatment of sleepdisordered breathing.
Am Rev Respir Dis, 158 (1998), pp. 691-699
[66.]
M. Behan, M.S. Brownfield.
Age-related changes in serotonin in the hypoglossal nucleus of rat: implications for sleep-disordered breathing.
Neurosci Lett, 267 (1999), pp. 133-136
[67.]
S.C. Veasey, K.A. Panckeri, E.A. Hoffman, A.I. Pack, J.C. Hendricks.
The effects of serotonin antagonists in an animal model of sleep-disordered breathing.
Am J Respir Crit Care Med, 153 (1996), pp. 776-786
[68.]
D.W. Hudgel, E.A. Gordon.
Serotonin-induced cortisol release in CPAP-treated obstructive sleep apnea patients.
Chest, 111 (1997), pp. 632-638
[69.]
H. Kraiczi, J. Hedner, P. Dahlöf, H. Ejnell, J. Carlson.
Effect of serotonin uptake inhibition on breathing during sleep and daytime symptoms in obstructive sleep apnea.
Sleep, 22 (1999), pp. 62-67
[70.]
M. Radulovacki, S. Trbovic, D.W. Carley.
Serotonin 5-HT3-receptor antagonist GR 38032F Supresses sleep apneas in rats.
Sleep, 21 (1998), pp. 131-136
Copyright © 2000. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?