Elsevier

Journal of Cardiology Cases

Volume 3, Issue 1, February 2011, Pages e40-e42
Journal of Cardiology Cases

Case Report
Instantaneous restoration of cardiac output by noninvasive positive pressure ventilation in a patient with obesity hypoventilation syndrome

https://doi.org/10.1016/j.jccase.2010.10.001Get rights and content
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Summary

We report a 30-year-old man with severe obesity hypoventilation syndrome (OHVS) complicated by right-sided heart failure. Polysomnography revealed severe obstructive sleep apnea with apnea–hypopnea index (AHI) 70.4/h and gradual decrease in minimum oxygen saturation (SpO2) from 86% before sleep to 36% during sleep. Cardiac output (CO) was suppressed from 3.9 L/min before sleep to 2.5 L/min during sleep. Noninvasive positive pressure ventilation (NPPV) treatment drastically restored CO to the level before sleep, and improved AHI to 9.4/h and minimum SpO2 to 87%. NPPV may provide rapid and powerful symptom relief in patients with OHVS complicated with right sided heart failure.

Keywords

Obesity hypoventilation syndrome
Sleep apnea syndrome
Heart failure
Cardiac output

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