Asthma diagnosis and treatmentObesity, smooth muscle, and airway hyperresponsiveness
References (25)
- et al.
Body mass index and asthma severity among adults presenting to the emergency department
Chest
(2003) - et al.
Effect of weight reduction on respiratory function and airway reactivity in obese women
Chest
(2004) Frozen objects: small airways, big breaths, and asthma
J Allergy Clin Immunol
(2000)- et al.
The delicate balance between fat and muscle: adipokines in metabolic disease and musculoskeletal inflammation
Curr Opin Pharmacol
(2004) - et al.
Leptin: Does it have any role in childhood asthma?
J Allergy Clin Immunol
(2004) - et al.
Effect of leptin on allergic airway responses in mice
J Allergy Clin Immunol
(2005) - et al.
PAI-1 promotes extracellular matrix deposition in the airways of a murine asthma model
Biochem Biophys Res Commun
(2002) - et al.
Association of being overweight with greater asthma symptoms in inner city black and Hispanic children
J Pediatr
(1998) - et al.
Obesity and asthma: directions for research
Am J Respir Crit Care Med
(2004) - et al.
Prospective study of body mass index, weight change, and risk of adult-onset asthma in women
Arch Intern Med
(1999)
Persistence of asthma symptoms during adolescence: role of obesity and age at onset of puberty
Am J Respir Crit Care Med
(2004)
Association of body mass index with the development of methacholine airway hyperresponsiveness in men: the Normative Aging Study
Thorax
(2002)
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A new approach for the detection of obesity-related airway obstruction in lung-healthy individuals
2022, Respiratory MedicineCitation Excerpt :The weaker response to inhalation therapy is well known [16,17], in line with improvements after bariatric surgery [28]. Often the link between asthma and obesity is attributed to immunological factors, including modulation of allergen responses by leptin and adiponectin [29–31], but mechanical factors have also been considered [6,9]. To identify the contribution of such factors acting externally on a healthy lung is relevant, to exclude misdiagnosis and unnecessary inhalation therapy, potentially with corticosteroids implying higher costs [32,33] and avoidable side effects [34,35].
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2019, Allergology InternationalBreast feeding, obesity, and asthma association: clinical and molecular views
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Guest editor: William W. Busse, MD
Supported by National Institutes of Health grants HL33009 and HL59682, ES00002, and a gift from Paul and Mary Finnegan.
Copyright © 2005 American Academy of Allergy, Asthma and Immunology. Published by Mosby, Inc. All rights reserved.