State of artExercise training after lung transplantation: A systematic review
Section snippets
Search strategy
A search of electronic databases, including Cochrane Central Registrar of Controlled Trials, MEDLINE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Physiotherapy Evidence Database (PEDro), and Excerpta Medica Database (EMBASE), was performed from inception to May 2009 for articles that evaluated the effects of exercise training after lung transplantation. The keywords used included organ transplantation, lung transplantation, transplantation, exercise, exercise training,
Results
Of the 1754 articles retrieved, only 8 met the inclusion criteria.15, 19, 20, 21, 22, 23, 24, 25 One article25 was further excluded because it involved a mixed sample of heart, heart-lung, lung, kidney, and liver transplant recipients. One abstract reporting a RCT of early rehabilitation after lung transplantation26 was ongoing at the time of this study and did not have sufficient data to be included in this review.
The 7 studies included in the review are summarized in Table 1. There were a
Discussion
This evidence shows that lung transplant recipients demonstrate impairments in exercise capacity, skeletal muscle function, and BMD. Preliminary data from 7 studies on exercise training shows positive effects on maximal and functional exercise capacity, skeletal muscle function, BMD, and HRQOL in lung transplant recipients. Exercise should therefore be included in the regular management of the patient before and after lung transplantation to address deconditioning and the side effects of
Disclosure statement
The authors acknowledge John Tagg and Sachi O'Haski from West Park Healthcare Centre, Toronto, Ontario, Canada, for their assistance with the electronic search and article retrieval.
Lisa Wickerson is supported in her graduate studies by fellowships through the Ontario Respiratory Care Society and the Canadian Lung Association. Dina Brooks holds a Canadian Research Chair in Rehabilitation in COPD.
None of the authors has a financial relationship with a commercial entity that has an interest in
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