Validation of the spanish version of the asthma control questionnaire
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2023, Journal of Allergy and Clinical ImmunologyCitation Excerpt :Moreover, unexplained superior ACQ score improvement of mepolizumab despite poor efficacy in improving lung function observed in this meta-analysis raises the concern that ACQ score might not capture important improvements based on pathophysiology. One possible explanation was that the included RCTs used either ACQ-5 or ACQ-6, which do not include the objective question on FEV1 accounting for the weak-to-moderate correlation between these ACQ versions and FEV1,46,47 in spite of the moderate-to-strong correlation between ACQ-7 and FEV1.48 However, the ACQ score is an important outcome, albeit subjective, because it captures a patient’s assessment of their own asthma control.
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Members of the Covalair Investigator Group are listed in the Acknowledgments.