array:23 [
  "pii" => "S0300289615310851"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)31085-1"
  "estado" => "S300"
  "fechaPublicacion" => "1994-04-01"
  "aid" => "71155"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
  "copyrightAnyo" => "1994"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 1994;30:181-4"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1351
    "formatos" => array:3 [
      "EPUB" => 55
      "HTML" => 666
      "PDF" => 630
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615310863"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)31086-3"
    "estado" => "S300"
    "fechaPublicacion" => "1994-04-01"
    "aid" => "71156"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1994;30:185-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1709
      "formatos" => array:3 [
        "EPUB" => 75
        "HTML" => 899
        "PDF" => 735
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Tratamiento del neumotórax con drenaje fino sin sello de agua"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "185"
          "paginaFinal" => "187"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Treatment of pneumothorax with small caliber chest tubes with no water seal"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "G. Varela, A. Arroyo, E. Larrú, V. Díaz-Hellín, P. Gámez"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "G."
              "apellidos" => "Varela"
            ]
            1 => array:2 [
              "nombre" => "A."
              "apellidos" => "Arroyo"
            ]
            2 => array:2 [
              "nombre" => "E."
              "apellidos" => "Larrú"
            ]
            3 => array:2 [
              "nombre" => "V."
              "apellidos" => "Díaz-Hellín"
            ]
            4 => array:2 [
              "nombre" => "P."
              "apellidos" => "Gámez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615310863?idApp=UINPBA00003Z"
    "url" => "/03002896/0000003000000004/v1_201509151156/S0300289615310863/v1_201509151156/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S030028961531084X"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)31084-X"
    "estado" => "S300"
    "fechaPublicacion" => "1994-04-01"
    "aid" => "71154"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "edi"
    "cita" => "Arch Bronconeumol. 1994;30:177-80"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 2394
      "formatos" => array:3 [
        "EPUB" => 62
        "HTML" => 681
        "PDF" => 1651
      ]
    ]
    "es" => array:7 [
      "idiomaDefecto" => true
      "titulo" => "Pleurodesis: aspectos polémicos"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "177"
          "paginaFinal" => "180"
        ]
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "F. Rodríguez Panadero"
          "autores" => array:1 [
            0 => array:2 [
              "nombre" => "F."
              "apellidos" => "Rodríguez Panadero"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028961531084X?idApp=UINPBA00003Z"
    "url" => "/03002896/0000003000000004/v1_201509151156/S030028961531084X/v1_201509151156/es/main.assets"
  ]
  "es" => array:13 [
    "idiomaDefecto" => true
    "titulo" => "Valoración del hemocultivo en la micobacteriosis diseminada"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "181"
        "paginaFinal" => "184"
      ]
    ]
    "autores" => array:2 [
      0 => array:4 [
        "autoresLista" => "M.C. Nogales, R. Aretio, E. Martín"
        "autores" => array:3 [
          0 => array:3 [
            "nombre" => "M.C."
            "apellidos" => "Nogales"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">1</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "R&#46;"
            "apellidos" => "Aretio"
          ]
          2 => array:2 [
            "nombre" => "E&#46;"
            "apellidos" => "Mart&#237;n"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Microbiolog&#237;a&#46; Hospital Universitario de Valme&#46; Sevilla"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "1"
            "correspondencia" => "Correspondencia&#58; Servicio de Microbiolog&#237;a&#46; Hospital Universitario de Valme&#46; Carretera de C&#225;diz&#44; s&#47;n&#46; 41014 Sevilla&#46;"
          ]
        ]
      ]
      1 => array:3 [
        "autoresLista" => "A&#46; Beiztegui, F&#46; Mu&#241;oz"
        "autores" => array:2 [
          0 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "Beiztegui"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "F&#46;"
            "apellidos" => "Mu&#241;oz"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:3 [
            "entidad" => "Servicio de Neumolog&#237;a&#46; Hospital Universitario de Valme&#46; Sevilla"
            "etiqueta" => "&#42;"
            "identificador" => "aff0010"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Evaluation of blood culture in disseminated mycobacteremia"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1993-03-18"
    "fechaAceptado" => "1993-07-28"
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:1 [
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El objetivo del estudio es evaluar la rentabilidad del hemocultivo en el diagn&#243;stico de micobacteriosis diseminada &#40;MBD&#41;&#46;</p><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Se llev&#243; a cabo un estudio prospectivo desde enero 1991 a julio de 1992&#44; de todos los hemocultivos realizados a enfermos con fiebre y sospecha de MBD&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se realizaron un total de 57 hemocultivos pertenecientes a 16 enfermos&#44; 14 VIH positivos &#40;87&#44;5&#37;&#41;&#44; diagnosticados de MBD&#46; Los hemocultivos se procesaron por la t&#233;cnica de lisiscentrifugaci&#243;n&#46; La identificaci&#243;n de las micobacterias se realiz&#243; por t&#233;cnica de hibridaci&#243;n con sonda de ADN&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Se detect&#243; crecimiento de micobacterias en 5 hemocultivos &#40;8&#44;7&#37;&#41;&#44; pertenecientes a 4 enfermos &#40;25&#37;&#41; &#40;3 VIH&#43;&#41;&#46; En tres de ellos se aisl&#243; M&#46; tuberculosis y en uno M&#46; avium&#46; El tiempo medio de aislamiento fue de 46 d&#237;as&#46; En todos los casos se aislaron micobacterias con anterioridad al hemocultivo en otras muestras&#44; M&#46; tuberculosis en 2 broncoaspirados &#40;BAS&#41;&#44; en 2 biopsias hep&#225;ticas &#40;BH&#41;&#44; 2 biopsias de bazo &#40;BB&#41;&#44; un lavado broncoalveolar &#40;LBA&#41;&#44; un esputo&#44; un LCR y una orina&#59; M&#46; avium se aisl&#243; en esputo y LBA&#46; Los 3 enfermos con aislamiento de M&#46; tuberculosis fallecieron a los 1&#44; 4 y 32 d&#237;as del ingreso&#46; De las 12 MBD con hemocultivos negativos &#40;11 VIH&#43;&#44; 92&#37;&#41;&#44; se aisl&#243; M&#46; tuberculosis en el 100&#37; de las muestras de ganglio y BB&#44; 90&#37; de las orinas&#44; 69&#37; de esputos&#44; 67&#37; de LBA y BH&#44; 63&#37; en BAS y 33&#37; en LCR&#46; Ninguno de estos enfermos falleci&#243; durante el ingreso&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Detectamos una baja rentabilidad del hemocultivo en el diagn&#243;stico de MBD&#46; El examen de otras muestras proporciona un diagn&#243;stico m&#225;s r&#225;pido&#46; La positividad del hemocultivo podr&#237;a ser un marcador pron&#243;stico&#46;</p></span>"
      ]
      "en" => array:1 [
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The objective of this study was to evaluate the usefulness of blood culture in the diagnosis of disseminated mycobacteremia &#40;DMB&#41;&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">This prospective study included all blood cultures done for patients with fever and under suspicion of having DMB between January 1991 and July 1992&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Fifty-seven blood samples from 16 patients were cultured&#59; 14 &#40;87&#46;5&#37;&#41; patients were HIV positive and all were diagnosed as having DMB&#46; The cultures were processed by lysiscentrifugation and identification of mycobacteria was by hybridization with a DNA probe&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Mycobacterial growth was detected in 5 cultures &#40;8&#46;7&#37;&#41; from 4 patients &#40;25&#37;&#41; &#40;3 HIV positive&#41;&#46; M&#46; tuberculosis was isolated in 3 and M&#46; avium in 1&#46; Mean time until isolation was 46 days&#46; In all cases mycobacteria were isolated in other samples before they were found in cultures&#58; M&#46; tuberculosis was isolated in 2 bronchial aspirates &#40;BAS&#41;&#44; 2 in liver tissue &#40;L&#41;&#44; 2 in spleen tissue &#40;S&#41;&#44; one in alveolar bronchial lavage&#44; one in sputum&#44; one in spinal fluid &#40;SF&#41; and one in uri&#241;e&#46; M&#46; avium was isolated in sputum and ALB&#46; The three patients in whom M&#46; tuberculosis was found died 1&#46;4 and 32 days after admission&#46; In samples from the 12 DMB patients with negative cultures &#40;11 HIV positive&#44; 92&#37;&#41;&#44; M&#46; tuberculosis was isolated in 100&#37; of ganglion and S samples&#44; 90&#37; in uri&#241;e&#44; 69&#37; in sputum&#44; 67&#37; in ABL and LB&#44; 63&#37; in BAS and 33&#37; in SF&#46; None of these patients died in hospital&#46;</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">We find blood culture to be of little use in the diagnosis of DMB&#46; Analysis of other samples leads to faster diagnosis&#46; A positive blood culture may be a prognositic indicator&#46;</p></span>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliograf&#237;a"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:22 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cultivation of tubercle bacilli from the circulating blood in miliary tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;C&#46; Clough"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am Rev Tuberc"
                        "fecha" => "1917"
                        "volumen" => "1"
                        "paginaInicial" => "598"
                        "paginaFinal" => "621"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Extrapulmonary tuberculosis in patients with human immunodeficiency viral infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46;W&#46; Shafer"
                            1 => "D&#46;S&#46; Kim"
                            2 => "J&#46;P&#46; Weiss"
                            3 => "J&#46;M&#46; Quale"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Medicine"
                        "fecha" => "1991"
                        "volumen" => "70"
                        "paginaInicial" => "384"
                        "paginaFinal" => "397"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1956280"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bacteremia due to Mycobacterium tuberculosis in patients with humano immunodeficiency virus infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "T&#46;W&#46; Barber"
                            1 => "D&#46;E&#46; Craven"
                            2 => "W&#46;R&#46; McCabe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Medicine"
                        "fecha" => "1990"
                        "volumen" => "69"
                        "paginaInicial" => "375"
                        "paginaFinal" => "383"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2122171"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Result of blood cultures for detection of mycobateria in AIDS patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46; Truffot-Pernot"
                            1 => "L&#46; Maury"
                            2 => "D&#46; Dautzenberg"
                            3 => "J&#46; Grosset"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Tubercle"
                        "fecha" => "1989"
                        "volumen" => "70"
                        "paginaInicial" => "187"
                        "paginaFinal" => "191"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2694553"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cumulative positivity rates of multiple blood cultures for patients with the acquired immunodeficiency syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46; Yagupsky"
                            1 => "T&#46; Menegus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Pathol Lab Med"
                        "fecha" => "1990"
                        "volumen" => "114"
                        "paginaInicial" => "923"
                        "paginaFinal" => "925"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2202274"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "High prevalence of tuberculosis in AIDS patients in Spain"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Bouza"
                            1 => "C&#46; Mart&#237;n-Scapa"
                            2 => "J&#46;C&#46; Bernaldo de Quiros"
                            3 => "D&#46; Mart&#237;nez-Hern&#225;ndez"
                            4 => "J&#46; Menarquez"
                            5 => "J&#46; G&#243;mez-Rodrigo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Clin Microbiol Infect Dis"
                        "fecha" => "1988"
                        "volumen" => "7"
                        "paginaInicial" => "785"
                        "paginaFinal" => "788"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3145865"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparison of BACTEC 13A medium and Dupont Isolator for the detection for Mycobacteremia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "F&#46;G&#46; Witebsky"
                            1 => "J&#46;F&#46; Keiser"
                            2 => "P&#46;S&#46; Conuille"
                            3 => "R&#46; Bryan"
                            4 => "C&#46;H&#46; Park"
                            5 => "R&#46; Walker"
                            6 => "S&#46;H&#46; Siddqui"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Microbiol"
                        "fecha" => "1988"
                        "volumen" => "26"
                        "paginaInicial" => "1&#46;501"
                        "paginaFinal" => "1&#46;505"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3265942"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparision of improved BACTEC and Lownestein-Jensen medium for culture of Mycobacteria from clinical specimen"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Anaygros"
                            1 => "D&#46; Astill"
                            2 => "T&#46; Lin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Microbiol"
                        "fecha" => "1990"
                        "volumen" => "28"
                        "paginaInicial" => "1&#46;228"
                        "paginaFinal" => "1&#46;290"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2280020"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Direct identification of Mycobacterium tuberculosis Mycobacterium avium and Mycobacterium intracellulare from amplified primary culture in Bactec media using DNA probes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E&#46;M&#46; Peterson"
                            1 => "R&#46; Lu"
                            2 => "C&#46; Floyd"
                            3 => "E&#46; Nakasone"
                            4 => "G&#46; Friedly"
                            5 => "L&#46;M&#46; de la Maza"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Microbiol"
                        "fecha" => "1989"
                        "volumen" => "27"
                        "paginaInicial" => "1&#46;453"
                        "paginaFinal" => "1&#46;457"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2687322"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The use of Zephiran in the isolation of M&#46; tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "I&#46; Krasnow"
                            1 => "L&#46;G&#46; Wayner"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Amer J Clin Pathol"
                        "fecha" => "1966"
                        "volumen" => "45"
                        "paginaInicial" => "352"
                        "paginaFinal" => "355"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mycobacteriae disease in patients with immunodeficiency virus infection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "T&#46; Modilevsky"
                            1 => "F&#46;R&#46; Satter"
                            2 => "P&#46;F&#46; Barnes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1989"
                        "volumen" => "149"
                        "paginaInicial" => "2&#46;201"
                        "paginaFinal" => "2&#46;205"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2688586"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Six cases of Mycobacterium tuberculosis bacteremia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "P&#46;P&#46; Barnes"
                            1 => "C&#46; Arevalo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect Dis"
                        "fecha" => "1987"
                        "volumen" => "156"
                        "paginaInicial" => "377"
                        "paginaFinal" => "379"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3110309"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hematogenous dissemination of Mycobacterium tuberculosis in patients with AIDS"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "R&#46;B&#46; Clark"
                            1 => "S&#46;L&#46; Blakley"
                            2 => "D&#46; Greer"
                            3 => "M&#46;H&#46; Smith"
                            4 => "W&#46; Brandon"
                            5 => "T&#46;L&#46; Wisniewski"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Inf Dis"
                        "fecha" => "1991"
                        "volumen" => "13"
                        "paginaInicial" => "1&#46;089"
                        "paginaFinal" => "1&#46;092"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sepsis por Mycobacterium tuberculosis en pacientes con SIDA"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:8 [
                            0 => "S&#46; Mattar"
                            1 => "M&#46; Morta"
                            2 => "L&#46; Drobnic"
                            3 => "P&#46; Hern&#225;ndez"
                            4 => "E&#46; Pallares"
                            5 => "J&#46;L&#46; Gimeno"
                            6 => "L&#46; Gea"
                            7 => "J&#46;M&#46; Torres"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Enf Infec Microbiol Clin"
                        "fecha" => "1992"
                        "volumen" => "10"
                        "paginaInicial" => "29"
                        "paginaFinal" => "31"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Frequency of Mycobaterium tuberculosis bacteremia in patients with tuberculosis in an area endemic for AIDS"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46;W&#46; Shafer"
                            1 => "R&#46; Goldberg"
                            2 => "M&#46; Sierra"
                            3 => "A&#46;E&#46; Glatt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/ajrccm/140.6.1727"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am Rev Respir Dis"
                        "fecha" => "1989"
                        "volumen" => "140"
                        "paginaInicial" => "1&#46;611"
                        "paginaFinal" => "1&#46;613"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2690707"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Blood culture value in the diagnostic of the disseminated tuberculosis in AIDS patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:9 [
                            0 => "J&#46; da Bouza"
                            1 => "M&#46; Di Leonardo"
                            2 => "J&#46; Benetucci"
                            3 => "J&#46; Gonz&#225;lez Montaner"
                            4 => "E&#46; Abbate"
                            5 => "M&#46; Corti"
                            6 => "M&#46; Compagnucci"
                            7 => "O&#46; Ortega"
                            8 => "L&#46; Astarloa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Six international Conference on AIDS&#44; San Francisco&#46; California&#44; Thb"
                        "fecha" => "1990"
                        "volumen" => "501"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Coraparative yield of blood culture for fungi and mycobacteria&#44; liver biopsy and bone marrow biopsy in the diagnosis of fever of undetermined origin in human immunodeficiency virus-infected patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "V&#46; Prego"
                            1 => "A&#46;E&#46; Glatt"
                            2 => "V&#46; Roy"
                            3 => "W&#46; Thelmo"
                            4 => "H&#46; Dinesoy"
                            5 => "J&#46;P&#46; Raufman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1990"
                        "volumen" => "150"
                        "paginaInicial" => "333"
                        "paginaFinal" => "336"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2302009"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mycobacteria and Cryptococci cultured from buffy coat of AIDS patients prior to symptomatology&#58; A rationale for early therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "E&#46;J&#46; Bottone"
                            1 => "B&#46; Damsker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "AIDS Research"
                        "fecha" => "1986"
                        "volumen" => "2"
                        "paginaInicial" => "343"
                        "paginaFinal" => "348"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3101713"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagnosis of Mycobacterium bacteremia in patients with acquired immunodeficiency syndrome by direct examination of blood films"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "R&#46;H&#46; Eng"
                            1 => "E&#46; Bishburg"
                            2 => "S&#46;M&#46; Smith"
                            3 => "A&#46; Maugia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Clin Microbiol"
                        "fecha" => "1989"
                        "volumen" => "27"
                        "paginaInicial" => "768"
                        "paginaFinal" => "769"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2498390"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mycobacteremia in acquired immunodeficiency syndrome Rapid diagnosis based on inclusions in the peripheral blood smear"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;H&#46; Godwin"
                            1 => "A&#46; Stopeck"
                            2 => "V&#46;T&#46; Ghang"
                            3 => "T&#46;A&#46; Godwin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Clin Pathol"
                        "fecha" => "1991"
                        "volumen" => "95"
                        "paginaInicial" => "369"
                        "paginaFinal" => "375"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1705093"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Direct visualization of Mycobacterium tuberculosis in a blood sample from a AIDS patients &#91;carta&#93;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "F&#46; Biron"
                            1 => "J&#46;C&#46; Reveil"
                            2 => "C&#46; Penalba"
                            3 => "A&#46; Boibieux"
                            4 => "J&#46;L&#46; Bertrand"
                            5 => "D&#46; Peyramond"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "AIDS"
                        "fecha" => "1990"
                        "volumen" => "4"
                        "paginaInicial" => "259"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2350447"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "El hemocultivo frente a otras muestras para el aislamiento de Micobacterias en pacientes con SIDA o VIH positivo"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "C&#46; Jim&#233;nez"
                            1 => "M&#46;T&#46; Revilla"
                            2 => "P&#46; Medina"
                            3 => "J&#46; March"
                            4 => "A&#46; Ortega"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1991"
                        "editorial" => "I Congreso Nacional sobre el SIDA"
                        "editorialLocalizacion" => "Madrid"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000003000000004/v1_201509151156/S0300289615310851/v1_201509151156/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9277"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000003000000004/v1_201509151156/S0300289615310851/v1_201509151156/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615310851?idApp=UINPBA00003Z"
]
Share
Journal Information
Vol. 30. Issue 4.
Pages 181-184 (April 1994)
Share
Share
Download PDF
More article options
Vol. 30. Issue 4.
Pages 181-184 (April 1994)
Full text access
Valoración del hemocultivo en la micobacteriosis diseminada
Evaluation of blood culture in disseminated mycobacteremia
Visits
4018
M.C. Nogales1, R. Aretio, E. Martín
Servicio de Microbiología. Hospital Universitario de Valme. Sevilla
A. Beiztegui*, F. Muñoz*
* Servicio de Neumología. Hospital Universitario de Valme. Sevilla
This item has received
Article information

El objetivo del estudio es evaluar la rentabilidad del hemocultivo en el diagnóstico de micobacteriosis diseminada (MBD).

Se llevó a cabo un estudio prospectivo desde enero 1991 a julio de 1992, de todos los hemocultivos realizados a enfermos con fiebre y sospecha de MBD.

Se realizaron un total de 57 hemocultivos pertenecientes a 16 enfermos, 14 VIH positivos (87,5%), diagnosticados de MBD. Los hemocultivos se procesaron por la técnica de lisiscentrifugación. La identificación de las micobacterias se realizó por técnica de hibridación con sonda de ADN.

Se detectó crecimiento de micobacterias en 5 hemocultivos (8,7%), pertenecientes a 4 enfermos (25%) (3 VIH+). En tres de ellos se aisló M. tuberculosis y en uno M. avium. El tiempo medio de aislamiento fue de 46 días. En todos los casos se aislaron micobacterias con anterioridad al hemocultivo en otras muestras, M. tuberculosis en 2 broncoaspirados (BAS), en 2 biopsias hepáticas (BH), 2 biopsias de bazo (BB), un lavado broncoalveolar (LBA), un esputo, un LCR y una orina; M. avium se aisló en esputo y LBA. Los 3 enfermos con aislamiento de M. tuberculosis fallecieron a los 1, 4 y 32 días del ingreso. De las 12 MBD con hemocultivos negativos (11 VIH+, 92%), se aisló M. tuberculosis en el 100% de las muestras de ganglio y BB, 90% de las orinas, 69% de esputos, 67% de LBA y BH, 63% en BAS y 33% en LCR. Ninguno de estos enfermos falleció durante el ingreso.

Detectamos una baja rentabilidad del hemocultivo en el diagnóstico de MBD. El examen de otras muestras proporciona un diagnóstico más rápido. La positividad del hemocultivo podría ser un marcador pronóstico.

The objective of this study was to evaluate the usefulness of blood culture in the diagnosis of disseminated mycobacteremia (DMB).

This prospective study included all blood cultures done for patients with fever and under suspicion of having DMB between January 1991 and July 1992.

Fifty-seven blood samples from 16 patients were cultured; 14 (87.5%) patients were HIV positive and all were diagnosed as having DMB. The cultures were processed by lysiscentrifugation and identification of mycobacteria was by hybridization with a DNA probe.

Mycobacterial growth was detected in 5 cultures (8.7%) from 4 patients (25%) (3 HIV positive). M. tuberculosis was isolated in 3 and M. avium in 1. Mean time until isolation was 46 days. In all cases mycobacteria were isolated in other samples before they were found in cultures: M. tuberculosis was isolated in 2 bronchial aspirates (BAS), 2 in liver tissue (L), 2 in spleen tissue (S), one in alveolar bronchial lavage, one in sputum, one in spinal fluid (SF) and one in uriñe. M. avium was isolated in sputum and ALB. The three patients in whom M. tuberculosis was found died 1.4 and 32 days after admission. In samples from the 12 DMB patients with negative cultures (11 HIV positive, 92%), M. tuberculosis was isolated in 100% of ganglion and S samples, 90% in uriñe, 69% in sputum, 67% in ABL and LB, 63% in BAS and 33% in SF. None of these patients died in hospital.

We find blood culture to be of little use in the diagnosis of DMB. Analysis of other samples leads to faster diagnosis. A positive blood culture may be a prognositic indicator.

Full text is only aviable in PDF
Bibliografía
[1.]
M.C. Clough.
Cultivation of tubercle bacilli from the circulating blood in miliary tuberculosis.
Am Rev Tuberc, 1 (1917), pp. 598-621
[2.]
R.W. Shafer, D.S. Kim, J.P. Weiss, J.M. Quale.
Extrapulmonary tuberculosis in patients with human immunodeficiency viral infection.
Medicine, 70 (1991), pp. 384-397
[3.]
T.W. Barber, D.E. Craven, W.R. McCabe.
Bacteremia due to Mycobacterium tuberculosis in patients with humano immunodeficiency virus infection.
Medicine, 69 (1990), pp. 375-383
[4.]
C. Truffot-Pernot, L. Maury, D. Dautzenberg, J. Grosset.
Result of blood cultures for detection of mycobateria in AIDS patients.
Tubercle, 70 (1989), pp. 187-191
[5.]
P. Yagupsky, T. Menegus.
Cumulative positivity rates of multiple blood cultures for patients with the acquired immunodeficiency syndrome.
Arch Pathol Lab Med, 114 (1990), pp. 923-925
[6.]
E. Bouza, C. Martín-Scapa, J.C. Bernaldo de Quiros, D. Martínez-Hernández, J. Menarquez, J. Gómez-Rodrigo, et al.
High prevalence of tuberculosis in AIDS patients in Spain.
Eur J Clin Microbiol Infect Dis, 7 (1988), pp. 785-788
[7.]
F.G. Witebsky, J.F. Keiser, P.S. Conuille, R. Bryan, C.H. Park, R. Walker, S.H. Siddqui.
Comparison of BACTEC 13A medium and Dupont Isolator for the detection for Mycobacteremia.
J Clin Microbiol, 26 (1988), pp. 1.501-1.505
[8.]
P. Anaygros, D. Astill, T. Lin.
Comparision of improved BACTEC and Lownestein-Jensen medium for culture of Mycobacteria from clinical specimen.
J Clin Microbiol, 28 (1990), pp. 1.228-1.290
[9.]
E.M. Peterson, R. Lu, C. Floyd, E. Nakasone, G. Friedly, L.M. de la Maza.
Direct identification of Mycobacterium tuberculosis Mycobacterium avium and Mycobacterium intracellulare from amplified primary culture in Bactec media using DNA probes.
J Clin Microbiol, 27 (1989), pp. 1.453-1.457
[10.]
I. Krasnow, L.G. Wayner.
The use of Zephiran in the isolation of M. tuberculosis.
Amer J Clin Pathol, 45 (1966), pp. 352-355
[11.]
T. Modilevsky, F.R. Satter, P.F. Barnes.
Mycobacteriae disease in patients with immunodeficiency virus infection.
Arch Intern Med, 149 (1989), pp. 2.201-2.205
[12.]
P.P. Barnes, C. Arevalo.
Six cases of Mycobacterium tuberculosis bacteremia.
J Infect Dis, 156 (1987), pp. 377-379
[13.]
R.B. Clark, S.L. Blakley, D. Greer, M.H. Smith, W. Brandon, T.L. Wisniewski.
Hematogenous dissemination of Mycobacterium tuberculosis in patients with AIDS.
Rev Inf Dis, 13 (1991), pp. 1.089-1.092
[14.]
S. Mattar, M. Morta, L. Drobnic, P. Hernández, E. Pallares, J.L. Gimeno, L. Gea, J.M. Torres.
Sepsis por Mycobacterium tuberculosis en pacientes con SIDA.
Enf Infec Microbiol Clin, 10 (1992), pp. 29-31
[15.]
R.W. Shafer, R. Goldberg, M. Sierra, A.E. Glatt.
Frequency of Mycobaterium tuberculosis bacteremia in patients with tuberculosis in an area endemic for AIDS.
Am Rev Respir Dis, 140 (1989), pp. 1.611-1.613
[16.]
J. da Bouza, M. Di Leonardo, J. Benetucci, J. González Montaner, E. Abbate, M. Corti, M. Compagnucci, O. Ortega, L. Astarloa.
Blood culture value in the diagnostic of the disseminated tuberculosis in AIDS patients.
Six international Conference on AIDS, San Francisco. California, Thb, 501 (1990),
[17.]
V. Prego, A.E. Glatt, V. Roy, W. Thelmo, H. Dinesoy, J.P. Raufman.
Coraparative yield of blood culture for fungi and mycobacteria, liver biopsy and bone marrow biopsy in the diagnosis of fever of undetermined origin in human immunodeficiency virus-infected patients.
Arch Intern Med, 150 (1990), pp. 333-336
[18.]
E.J. Bottone, B. Damsker.
Mycobacteria and Cryptococci cultured from buffy coat of AIDS patients prior to symptomatology: A rationale for early therapy.
AIDS Research, 2 (1986), pp. 343-348
[19.]
R.H. Eng, E. Bishburg, S.M. Smith, A. Maugia.
Diagnosis of Mycobacterium bacteremia in patients with acquired immunodeficiency syndrome by direct examination of blood films.
J Clin Microbiol, 27 (1989), pp. 768-769
[20.]
J.H. Godwin, A. Stopeck, V.T. Ghang, T.A. Godwin.
Mycobacteremia in acquired immunodeficiency syndrome Rapid diagnosis based on inclusions in the peripheral blood smear.
Am J Clin Pathol, 95 (1991), pp. 369-375
[21.]
F. Biron, J.C. Reveil, C. Penalba, A. Boibieux, J.L. Bertrand, D. Peyramond.
Direct visualization of Mycobacterium tuberculosis in a blood sample from a AIDS patients [carta].
AIDS, 4 (1990), pp. 259
[22.]
C. Jiménez, M.T. Revilla, P. Medina, J. March, A. Ortega.
El hemocultivo frente a otras muestras para el aislamiento de Micobacterias en pacientes con SIDA o VIH positivo.
I Congreso Nacional sobre el SIDA, (1991),
Copyright © 1994. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?