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Vol. 14. Issue 1.
Pages 1-4 (January - March 1978)
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Vol. 14. Issue 1.
Pages 1-4 (January - March 1978)
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La inmunidad celular y la respuesta a la quimioterapia en pacientes afectos de cancer de pulmon metastasico
Cellular immunity and response to chemotherapy of patients affected with metastatic lung cancer
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E. Simó-Camps*, F. Manresa**
* Jefe del Servicio de Medicina Interna. Residencia Virgen de la Cinta. Tortosa. Tarragona.
** Jefe clínico del Instituto de Neumologia Clínica Ntra. Sra. de la Merced. Barcelona
J.M.a Vich
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Resumen

Se estudian 138 pacientes afectos de carcinoma pulmonar metastásico en su aspecto inmunológico.

Los estudios in vitro e in vivo de la inmunidad celular ponen de manifiesto que existe correlación entre una buena respuesta a la quimioterapia y la existencia de una respuesta inmune positiva frente a los parámetros estudiados en este grupo de enfermos. El 84,3% de enfermos que mejoraron clínicamente tenían respuestas inmunes positivas, mientras que únicamente 12,7% con respuestas inmunológicas favorables remitieron clínicamente.

Summary

The authors study the cases of 138 patients affected with metastasic lung cáncer in their immunological aspects.

Studies in vitro and in vivo of the cellular immunity show that a correlation exists between a good response to chemotherapy and the existence of a positive immune respone to the parameters studied in this group of patients. Of the patients that improved clinically, 84.3% had positive immune responses, while only 12.7% with favorable immunological responses showed clinical remission.

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W.J. Catalona, P.T. Taylor, A.S. Raboson, P.B. Chretien.
A method for D.N.C.B. contact sensibilazation. A clinicopathology study.
New England J. Med., 286 (1972), pp. 399
[45.]
J.M. Moragas, A. Anguera.
Indice de transformación blástica de los linfocitos en las farmacodermias.
Rev. Clin. Esp., 124 (1972), pp. 3
[46.]
J. Wybran, H.H. Fudenberg.
Rosette formation, a test for cellular immunity.
Trans. Ass. Amer. Phys., 84 (1971), pp. 239
[47.]
J. Wybran, H.H. Fundenberg.
Thymus-derived rosette-forminf cells.
New Engl. J. Med., 288 (1973), pp. 710
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A.M. Anthony, G.H. Templeman, K.E. Madsen, M.K. Mason.
The pronostic significance of DHS skin tests in patients with carcinoma of bronchus.
Cancer, 34 (1974), pp. 1.091
[49.]
L.A. Dellon, Cl. Potyin, P.B. Chretien.
Thymus-dependent lymphocyte levels in bronchogenic carcinoma: Correlation with histology, clinical stage and clinical case after surgical treatment.
Cancer, 35 (1975), pp. 387
Copyright © 1978. Sociedad Española de Neumología y Cirugía Torácica
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