TY - JOUR T1 - The BIOMEPOC Project: Personalized Biomarkers and Clinical Profiles in Chronic Obstructive Pulmonary Disease JO - Archivos de Bronconeumología T2 - AU - Gea,Joaquim AU - Pascual,Sergi AU - Castro-Acosta,Ady AU - Hernández-Carcereny,Carmen AU - Castelo,Robert AU - Márquez-Martín,Eduardo AU - Montón,Concepción AU - Palou,Alexandre AU - Faner,Rosa AU - Furlong,Laura I. AU - Seijo,Luis AU - Sanz,Ferran AU - Torà,Montserrat AU - Vilaplana,Carles AU - Casadevall,Carme AU - López-Campos,José Luis AU - Monsó,Eduard AU - Peces-Barba,Germán AU - Cosío,Borja G. AU - Agustí,Alvar SN - 15792129 M3 - 10.1016/j.arbr.2018.12.010 DO - 10.1016/j.arbr.2018.12.010 UR - https://archbronconeumol.org/en-the-biomepoc-project-personalized-biomarkers-articulo-S1579212918304348 AB - Chronic obstructive pulmonary disease (COPD) is an entity with a heterogeneous presentation. For this reason, attempts have been made to characterize different phenotypes and endotypes to enable a more individualized approach. The aim of the Biomarkers in COPD (BIOMEPOC) project is to identify useful biomarkers in blood to improve the characterization of patients. Clinical data and blood samples from a group of patients and healthy controls will be analyzed. The project will consist of an exploration phase and a validation phase. Analytical parameters in blood will be determined using standard techniques and certain ‘omics’ (transcriptomics, proteomics, and metabolomics). The former will be hypothesis-driven, whereas the latter will be exploratory. Finally, a multilevel analysis will be conducted. Currently, 269 patients and 83 controls have been recruited, and sample processing is beginning. Our hope is to use the results to identify new biomarkers that, alone or combined, will allow a better characterization of patients. ER -