TY - JOUR T1 - Tolerance and Safety of 5 Models of Sedation During Endobronchial Ultrasound JO - Archivos de Bronconeumología T2 - AU - Cases Viedma,Enrique AU - Andreo García,Felipe AU - Flandes Aldeyturriaga,Javier AU - Reig Mezquida,Juan Pablo AU - Briones Gómez,Andrés AU - Vila Caral,Pere AU - Fernández-Navamuel Basozabal,Iker AU - Centeno Clemente,Carmen Ángela AU - Campo Campo,Felipe AU - Sánchez Martínez,Estefanía AU - Sanchis Moret,Francisca AU - Manjón Pérez,Josefina AU - Sánchez Yepes,Marina SN - 15792129 M3 - 10.1016/j.arbr.2015.11.004 DO - 10.1016/j.arbr.2015.11.004 UR - https://archbronconeumol.org/en-tolerance-safety-5-models-sedation-articulo-S1579212915003535 AB - IntroductionSedation during endobronchial ultrasound (EBUS) is essential due to the long duration of this procedure. We evaluated different models of sedation and their complications. MethodA multicenter, prospective, observational study of 307 patients undergoing EBUS was conducted. Patients were sedated with: (a) midazolam bolus; (b) propofol infusion; (c) midazolam bolus and propofol infusion; (d) propofol infusion and remifentanil infusion, or (e) midazolam bolus and fentanyl bolus, and clinical variables were collected. Patients were asked to complete a satisfaction survey following the test. ResultsPatients per sedation model were: A 24, B 37, C 107, D 62 and E 77. Scores for perceived sensations of recall, pain, cough, dyspnea and prolonged examination (0.65±1.11, 0.3±0.73, 0.46±0.9, 0.29±0.73, and 0.59±0.96, respectively) were lower compared to fear and nervousness before the examination (1.26±1.37 and 1.5±1.41, respectively). High levels of indifference to repeating the procedure (1.49±1.3) and a reported pleasant feeling during the test (1.23±1.17), with low levels of anxiety (0.49±0.85) and discomfort (0.62±1.1), show that different models of sedation were well tolerated. Almost half the patients (46.6%) did not report any “worst moment” during the procedure, and 89.6% were willing to undergo a repeat test. The E and C models presented fewest complications (12.9% and 31.7%, respectively), and all were resolved with simple therapeutic measures. ConclusionsThe models of sedation evaluated were well tolerated and most patients were willing to undergo repeat EBUS. Complications were few and easily resolved. ER -