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(B) Chest computed tomography scan showing the bilateral hilar and mediastinal lymphadenopathy. (C) [18F]-fluorodeoxyglucose positron emission tomography scan showing the so-called “lambda (λ) sign”, indicating a high uptake in the bilateral hilar and mediastinal lymphadenopathy with a prominent right paratracheal region.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Yu Matsumoto, Masahiro Yamasaki, Naoko Matsumoto, Masaya Taniwaki, Noboru Hattori" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Yu" "apellidos" => "Matsumoto" ] 1 => array:2 [ "nombre" => "Masahiro" "apellidos" => "Yamasaki" ] 2 => array:2 [ "nombre" => "Naoko" "apellidos" => "Matsumoto" ] 3 => array:2 [ "nombre" => "Masaya" "apellidos" => "Taniwaki" ] 4 => array:2 [ "nombre" => "Noboru" "apellidos" => "Hattori" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1579212920300318" "doi" => "10.1016/j.arbr.2019.03.030" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212920300318?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028961930119X?idApp=UINPBA00003Z" "url" => "/03002896/0000005600000003/v2_202003070709/S030028961930119X/v2_202003070709/en/main.assets" ] ] "itemSiguiente" => array:18 [ "pii" => "S1579212920300045" "issn" => "15792129" "doi" => "10.1016/j.arbr.2019.08.006" "estado" => "S300" "fechaPublicacion" => "2020-03-01" "aid" => "2274" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Arch Bronconeumol. 2020;56:176-8" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1 "HTML" => 1 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific Letter</span>" "titulo" => "Ulcerative Colitis and Bronchiectasis: Can Treatment with Tofacitinib Have an Impact on Respiratory Symptoms?" 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(c) Axial contrast-enhanced CT scan of the pelvis in soft tissue window, showing sigmoid colon wall thickening and submucosal edema of chronic appearance, related with the patient’s inflammatory bowel manifestation.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Francisco Xavier León-Román, Francisco Mesonero-Gismero, Beatriz Pintado-Cort, Alfonso López-Frías López-Jurado, Luis Máiz-Carro, Luis Gorospe-Sarasúa, Edwin Mercedes-Noboa, Joaquín Asensio-Sánchez, Antonio López-San Román, Rosa Nieto-Royo" "autores" => array:10 [ 0 => array:2 [ "nombre" => "Francisco Xavier" "apellidos" => "León-Román" ] 1 => array:2 [ "nombre" => "Francisco" "apellidos" => "Mesonero-Gismero" ] 2 => array:2 [ "nombre" => "Beatriz" "apellidos" => "Pintado-Cort" ] 3 => array:2 [ "nombre" => "Alfonso López-Frías" "apellidos" => "López-Jurado" ] 4 => array:2 [ "nombre" => "Luis" "apellidos" => "Máiz-Carro" ] 5 => array:2 [ "nombre" => "Luis" "apellidos" => "Gorospe-Sarasúa" ] 6 => array:2 [ "nombre" => "Edwin" "apellidos" => "Mercedes-Noboa" ] 7 => array:2 [ "nombre" => "Joaquín" "apellidos" => "Asensio-Sánchez" ] 8 => array:2 [ "nombre" => "Antonio" "apellidos" => "López-San Román" ] 9 => array:2 [ "nombre" => "Rosa" "apellidos" => "Nieto-Royo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289619303680" "doi" => "10.1016/j.arbres.2019.08.013" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289619303680?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212920300045?idApp=UINPBA00003Z" "url" => "/15792129/0000005600000003/v1_202003020616/S1579212920300045/v1_202003020616/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S157921292030032X" "issn" => "15792129" "doi" => "10.1016/j.arbr.2019.03.031" "estado" => "S300" "fechaPublicacion" => "2020-03-01" "aid" => "2136" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2020;56:173" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Benign Tracheal Stenosis: 7 Years of Follow-up Tracheal Stenting" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "173" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Estenosis traqueal benigna: 7 años de seguimiento tras colocación de stent" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1654 "Ancho" => 2833 "Tamanyo" => 329380 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(a) Axial cut of chest CT scan showing narrowing of the trachea resulting in stenosis >50%. 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(B) Chest computed tomography scan showing the bilateral hilar and mediastinal lymphadenopathy. (C) [18F]-fluorodeoxyglucose positron emission tomography scan showing the so-called “lambda (λ) sign”, indicating a high uptake in the bilateral hilar and mediastinal lymphadenopathy with a prominent right paratracheal region.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 43-year-old woman was referred to our hospital with bilateral hilar lymphadenopathy on chest radiography. She was examined by enhanced computed tomography scan, and bilateral hilar and mediastinal lymphadenopathy was detected. [18F]-fluorodeoxyglucose (FDG) positron emission tomography (PET) showed a high uptake in the above-mentioned lymphadenopathy, demonstrated by the so-called “lambda (λ) sign” (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>); therefore, sarcoidosis was suspected. A granuloma in the lymph node specimen and a high CD4/CD8 ratio of BAL were detected on endobronchial ultrasound-guided needle aspiration of the mediastinal lymph node and bronchoalveolar lavage (BAL) fluid examination. Therefore, she was diagnosed with sarcoidosis. As no sarcoid lesions were detected in other organs, such as heart, eyes, and skin, she was followed-up with no treatment.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The lambda sign means that a bilateral hilar and mediastinal lymphadenopathy with a prominent right paratracheal region on gallium scintigraphy gives the impression of an uptake pattern shaped as a “λ”.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> This sign shows high specificity for sarcoidosis.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> In a recent report, the lambda sign was also observed on an [18F]-FDG PET.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a> It has remarkable sensitivity in detection of occult disease sites, hence providing biopsy guidance.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a> A typical lambda sign supports the diagnosis of sarcoidosis and reinforces the indication to perform appropriate examinations.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2197 "Ancho" => 1505 "Tamanyo" => 186463 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Chest radiograph showing bilateral hilar lymphadenopathy. (B) Chest computed tomography scan showing the bilateral hilar and mediastinal lymphadenopathy. (C) [18F]-fluorodeoxyglucose positron emission tomography scan showing the so-called “lambda (λ) sign”, indicating a high uptake in the bilateral hilar and mediastinal lymphadenopathy with a prominent right paratracheal region.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0020" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recognition of distinctive patterns of gallium-67 distribution in sarcoidosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S.B. Sulavik" 1 => "R.P. Spencer" 2 => "D.A. Weed" 3 => "H.R. Shapiro" 4 => "S.T. Shiue" 5 => "R.J. 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Pfannenberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur J Nucl Med Imaging" "fecha" => "2011" "volumen" => "38" "paginaInicial" => "603" "itemHostRev" => array:3 [ "pii" => "S1474442212700170" "estado" => "S300" "issn" => "14744422" ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0030" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnosis of pulmonary sarcoidosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D. Israel-Biet" 1 => "D. Valeyre" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/MCP.0b013e3283645950" "Revista" => array:6 [ "tituloSerie" => "Curr Opin Pulm Med" "fecha" => "2013" "volumen" => "19" "paginaInicial" => "510" "paginaFinal" => "515" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23880701" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005600000003/v1_202003020616/S1579212920300318/v1_202003020616/en/main.assets" "Apartado" => array:4 [ "identificador" => "21342" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Clinical Image" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005600000003/v1_202003020616/S1579212920300318/v1_202003020616/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212920300318?idApp=UINPBA00003Z" ]
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