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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Background and objectives</span><p class="elsevierStyleSimplePara elsevierViewall">A few recent epidemiological findings indicate a link between atherosclerosis and some lung functions&#46; We studied further the relation between calcified chest atherosclerosis as seen in computed tomography &#40;CT&#41; and several lung functional parameters&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Male construction workers originally screened for occupational lung cancer with CT had their chest atherosclerosis &#40;aorta&#44; the origins of its cervical branches&#44; the coronary arteries and heart valves&#41; visually classified&#46; The relation between the atherosclerotic calcification scores and lung function &#40;total lung capacity &#91;TLC&#93;&#44; forced expiratory volume in one second &#91;FEV<span class="elsevierStyleInf">1</span>&#37;&#93;&#44; forced vital capacity &#91;FVC&#37;&#93;&#44; maximal expiratory flow when 50&#37; of FVC remains to be exhaled&#44; total and specific diffusing capacities&#59; all above expressed as percent of predicted value&#44; and the FEV<span class="elsevierStyleInf">1</span>&#47;FVC&#37; ratio&#41; were studied with the general linear model adjusted for smoking&#44; exposure years for asbestos&#44; and body mass index &#40;n &#61; 432&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">All lung functions except TLC showed significant negative associations with calcifications in aorta and in its branches&#46; TLC showed such association only with atherosclerosis in the ascending aorta&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Aortic atherosclerosis seems to be related with poor lung function&#46; This may be due to deteriorated bronchial circulation&#44; but other mechanisms can also be involved&#46; Lung function poorer than would be expected due to pulmonary reasons may indicate aortic atherosclerosis&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Varios hallazgos epidemiol&#243;gicos recientes indican que hay una conexi&#243;n entre la aterosclerosis y algunas funciones pulmonares&#46; Examinamos en m&#225;s detalle la relaci&#243;n entre la aterosclerosis calcificada de t&#243;rax&#44; seg&#250;n se visualiza en la tomograf&#237;a computarizada &#40;TAC&#41;&#44; y varios par&#225;metros de funci&#243;n pulmonar&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">En obreros de la construcci&#243;n masculinos a quienes inicialmente se realiz&#243; una TAC para la detecci&#243;n precoz de c&#225;ncer de pulm&#243;n ocupacional&#44; se efectu&#243; tambi&#233;n una clasificaci&#243;n visual de la aterosclerosis en la zona tor&#225;cica &#40;aorta&#44; origen de arterias del cayado a&#243;rtico&#44; arterias coronarias y v&#225;lvulas card&#237;acas&#41;&#46; Se evalu&#243; la relaci&#243;n entre las puntuaciones de la calcificaci&#243;n ateroscler&#243;tica y los par&#225;metros de funci&#243;n pulmonar &#8211;capacidad pulmonar total &#40;TLC&#41;&#44; volumen espiratorio forzado en el primer segundo &#40;FEV<span class="elsevierStyleInf">1</span>&#37;&#41;&#44; capacidad vital forzada &#40;FVC&#37;&#41;&#44; flujo espiratorio m&#225;ximo cuando queda un 50&#37; de la FVC por espirar y capacidades de difusi&#243;n total y espec&#237;fica &#40;todos ellos expresados como porcentajes del valor predicho&#41;&#44; as&#237; como el cociente FEV<span class="elsevierStyleInf">1</span>&#47;FVC&#37;&#8211; con un modelo lineal general ajustado para tabaquismo&#44; a&#241;os de exposici&#243;n al asbesto e &#237;ndice de masa corporal &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>432&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Todos los par&#225;metros de la funci&#243;n pulmonar&#44; salvo la TLC&#44; mostraron asociaciones negativas y significativas con la calcificaci&#243;n de la aorta y de sus ramas&#46; La TLC s&#243;lo mostr&#243; tal asociaci&#243;n con la aterosclerosis en la aorta ascendente&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La aterosclerosis a&#243;rtica parece estar relacionada con una funci&#243;n pulmonar deficiente&#46; Esto puede deberse al deterioro de la circulaci&#243;n bronquial&#44; pero tambi&#233;n pueden intervenir otros mecanismos&#46; Una funci&#243;n pulmonar m&#225;s deficiente de lo esperado seg&#250;n las condiciones pulmonares puede indicar aterosclerosis a&#243;rtica&#46;</p>"
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Original article
Relation Between Atherosclerotic Calcifications Detected in Chest Computed Tomography and Lung Function
Relación entre las calcificaciones ateroscleróticas en el tórax detectadas mediante tomografía computarizada y la función pulmonar
Tapio Vehmasa,
Corresponding author
tapio.vehmas@ttl.fi

Corresponding author.
, Asta Hiltinunenb, Päivi Leino-Arjasa, Päivi Piiriläc
a Health and Work Ability, Finnish Institute of Occupational Health, Helsinki, Finland
b Department of Radiology, Central Hospital of Länsi-Pohja, Kemi, Finland
c Department of Clinical Physiology, Helsinki University Hospital, HUSLAB, Helsinki, Finland
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        "resumen" => "<span class="elsevierStyleSectionTitle">Introducci&#243;n</span><p class="elsevierStyleSimplePara elsevierViewall">Varios hallazgos epidemiol&#243;gicos recientes indican que hay una conexi&#243;n entre la aterosclerosis y algunas funciones pulmonares&#46; Examinamos en m&#225;s detalle la relaci&#243;n entre la aterosclerosis calcificada de t&#243;rax&#44; seg&#250;n se visualiza en la tomograf&#237;a computarizada &#40;TAC&#41;&#44; y varios par&#225;metros de funci&#243;n pulmonar&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">En obreros de la construcci&#243;n masculinos a quienes inicialmente se realiz&#243; una TAC para la detecci&#243;n precoz de c&#225;ncer de pulm&#243;n ocupacional&#44; se efectu&#243; tambi&#233;n una clasificaci&#243;n visual de la aterosclerosis en la zona tor&#225;cica &#40;aorta&#44; origen de arterias del cayado a&#243;rtico&#44; arterias coronarias y v&#225;lvulas card&#237;acas&#41;&#46; Se evalu&#243; la relaci&#243;n entre las puntuaciones de la calcificaci&#243;n ateroscler&#243;tica y los par&#225;metros de funci&#243;n pulmonar &#8211;capacidad pulmonar total &#40;TLC&#41;&#44; volumen espiratorio forzado en el primer segundo &#40;FEV<span class="elsevierStyleInf">1</span>&#37;&#41;&#44; capacidad vital forzada &#40;FVC&#37;&#41;&#44; flujo espiratorio m&#225;ximo cuando queda un 50&#37; de la FVC por espirar y capacidades de difusi&#243;n total y espec&#237;fica &#40;todos ellos expresados como porcentajes del valor predicho&#41;&#44; as&#237; como el cociente FEV<span class="elsevierStyleInf">1</span>&#47;FVC&#37;&#8211; con un modelo lineal general ajustado para tabaquismo&#44; a&#241;os de exposici&#243;n al asbesto e &#237;ndice de masa corporal &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>432&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Todos los par&#225;metros de la funci&#243;n pulmonar&#44; salvo la TLC&#44; mostraron asociaciones negativas y significativas con la calcificaci&#243;n de la aorta y de sus ramas&#46; La TLC s&#243;lo mostr&#243; tal asociaci&#243;n con la aterosclerosis en la aorta ascendente&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La aterosclerosis a&#243;rtica parece estar relacionada con una funci&#243;n pulmonar deficiente&#46; Esto puede deberse al deterioro de la circulaci&#243;n bronquial&#44; pero tambi&#233;n pueden intervenir otros mecanismos&#46; Una funci&#243;n pulmonar m&#225;s deficiente de lo esperado seg&#250;n las condiciones pulmonares puede indicar aterosclerosis a&#243;rtica&#46;</p>"
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ISSN: 15792129
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