Correspondence: Dr. I. Sampablo. Servicio del Aparato Respiratorio. Instituto Universitario Dexeus. C/Escoles Pies, 78. 08017 Barcelona. España
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array:2 [ "titulo" => "Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G Di Chiara" 1 => "A Imperato" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Proc Natl Acad Sci" "fecha" => "1988" "volumen" => "85" "paginaInicial" => "5274" "paginaFinal" => "5278" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Self administered nicotine activates the mesolimbic, dopamine system through the ventral tegmental area" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "WA Corrigall" 1 => "K Coen" 2 => "K Adamson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Brain Res" "fecha" => "1994" "volumen" => "653" "paginaInicial" => "278" "paginaFinal" => "284" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7982062" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "FE Pointieri" 1 => "G Tanda" 2 => "F Orzi" 3 => "G Di Chiara" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/382255a0" "Revista" => array:6 [ "tituloSerie" => "Nature" "fecha" => "1996" "volumen" => "382" "paginaInicial" => "255" "paginaFinal" => "257" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8717040" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The pharmacology and neural circuitry of sensitization to psychostimulants" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P Kalivas" 1 => "B Sorg" 2 => "M Hooks" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Behav Pharmacol" "fecha" => "1993" "volumen" => "4" "paginaInicial" => "315" "paginaFinal" => "334" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11224200" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M Benwell" 1 => "D Balfour" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br J Pharmacol" "fecha" => "1992" "volumen" => "105" "paginaInicial" => "849" "paginaFinal" => "856" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacology of nicotine: addiction and therapeutics" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "N Benowitz" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1146/annurev.pa.36.040196.003121" "Revista" => array:6 [ "tituloSerie" => "Annu Rev Pharmacol Toxicol" "fecha" => "1996" "volumen" => "36" "paginaInicial" => "597" "paginaFinal" => "613" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8725403" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Normativa para el tratamiento del tabaquismo" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Grupo de trabajo de tratamiento del tabaquismo SEPAR" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1999" "volumen" => "35" "paginaInicial" => "499" "paginaFinal" => "506" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10618751" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treating tobacco use and dependence: an evidence-based clinical practice guideline for tobacco cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J Anderson" 1 => "D Jorenby" 2 => "W Scott" 3 => "M Fiore" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2002" "volumen" => "121" "paginaInicial" => "932" "paginaFinal" => "941" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11888979" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Perfil de los fumadores que solicitan tratamiento en una unidad de tabaquismo" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "I Nerín" 1 => "A Crucelagui" 2 => "A Mas" 3 => "D Guillén" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2003" "volumen" => "93" "paginaInicial" => "298" "paginaFinal" => "302" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "National Institute for Clinical Excellence (London). Guidance on the use of nicotine replacement therapy (NRT) and bupropion for smoking cessation. Technology Appraisal Guidance 39, March 2002." ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Estado actual y futuras terapias farmacológicas en la deshabituación tabáquica" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A Pérez Trullén" 1 => "M Clemente" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2001" "volumen" => "37" "paginaInicial" => "184" "paginaFinal" => "196" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11412504" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is clonidine an effective smoking cessation therapy?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S Gourlay" 1 => "N Benowitz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Drugs" "fecha" => "1995" "volumen" => "50" "paginaInicial" => "197" "paginaFinal" => "207" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8521754" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "LF Stead" 1 => "JR Hughes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Lobeline for smoking cessation (Cochrane Review). Cochrane Library" "fecha" => "2001" "editorial" => "Update Software" "editorialLocalizacion" => "Oxford" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mecamylamine does not precipitate withdrawal in cigarette smokers" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T Eissemberg" 1 => "R Griffiths" 2 => "M Stitzer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Psychopharmacology" "fecha" => "1996" "volumen" => "127" "paginaInicial" => "328" "paginaFinal" => "336" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8923568" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T Lancaster" 1 => "L Stead" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Individual behavioural counselling for smoking cessation (Cochrane Review). The Cochrane library" "fecha" => "2001" "editorial" => "Update Software" "editorialLocalizacion" => "Oxford" ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L Stead" 1 => "T Lancaster" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Group behavioural therapy programmes for smoking cessation (Cochrane Review). The Cochrane library" "fecha" => "2001" "editorial" => "Update Software" "editorialLocalizacion" => "Oxford" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A clinical practice guideline for treating tobacco use and dependence" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A US Public Health Service Report" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "JAMA" "fecha" => "2000" "volumen" => "283" "paginaInicial" => "3244" "paginaFinal" => "3254" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10866874" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bupropion: a review of its mechanism of antidepressant activity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "JA Ascher" 1 => "JO Cole" 2 => "JP Feighner" 3 => "RM Ferris" 4 => "HC Fibiger" 5 => "RN Golden" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Psychiatry" "fecha" => "1995" "volumen" => "56" "paginaInicial" => "395" "paginaFinal" => "401" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7665537" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The pharmacology underlying pharmacotherapy for tobacco dependence: a focus on bupropion" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "DJ Balfour" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Clin Pract" "fecha" => "2001" "volumen" => "55" "paginaInicial" => "53" "paginaFinal" => "57" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11219320" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A comparison of sustained-release bupropion and placebo for smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "RD Hurt" 1 => "DP Sachs" 2 => "ED Glover" 3 => "KP Offord" 4 => "JA Johnston" 5 => "LC Dale" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199710233371703" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1997" "volumen" => "337" "paginaInicial" => "1195" "paginaFinal" => "1202" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9337378" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "DE Jorenby" 1 => "SJ Leischow" 2 => "MA Nides" 3 => "SI Rennard" 4 => "JA Johnston" 5 => "AR Hughes" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199903043400903" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1999" "volumen" => "340" "paginaInicial" => "685" "paginaFinal" => "691" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10053177" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A multicentre, randomized, double-blind, placebo-controlled, 1 year study of bupropion for smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "P Tonnesen" 1 => "S Tonstad" 2 => "A Hjalmarson" 3 => "F Lebargy" 4 => "P van Spiegel" 5 => "A Hider" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Intern Med" "fecha" => "2003" "volumen" => "254" "paginaInicial" => "184" "paginaFinal" => "192" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12859700" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Asociación de bupropión y parches de nicotina como terapia para dejar de fumar" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "I Sampablo Lauro" 1 => "L Lores" 2 => "F Coll" 3 => "P Rabasa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2000" "volumen" => "36" "paginaInicial" => "377" "paginaFinal" => "380" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11000926" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bupropion hydrochloride induced serum sickness-like reaction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A Tripathi" 1 => "PA Greenberger" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Ann Allergy Asthma Inmmunol" "fecha" => "1999" "volumen" => "83" "paginaInicial" => "165" "paginaFinal" => "166" ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Development of depression during placebo-controlled trials of bupropion for smoking cessation: case reports" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "CA Patten" 1 => "TA Rummans" 2 => "IT Croghan" 3 => "RD Hurt" 4 => "JT Hays" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Psychiatry" "fecha" => "1999" "volumen" => "60" "paginaInicial" => "436" "paginaFinal" => "441" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10453796" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of bupropion sustained-release on cigarette craving after smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M Durcan" 1 => "G Deener" 2 => "J White" 3 => "J Johnston" 4 => "D Gonzales" 5 => "R Niaura" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Ther" "fecha" => "2002" "volumen" => "24" "paginaInicial" => "540" "paginaFinal" => "551" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12017399" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bupropion for smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L Dale" 1 => "E Glover" 2 => "D Sachs" 3 => "D Schroeder" 4 => "K Offord" 5 => "I Croghan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Chest" "fecha" => "2001" "volumen" => "119" "paginaInicial" => "1357" "paginaFinal" => "1364" ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Deshabituación tabáquica y bupropión: la ansiedad y la depresión como índices de eficacia terapéutica" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "I Sampablo Lauro" 1 => "JM Carreras" 2 => "L Lores" 3 => "M Quesada" 4 => "F Coll" 5 => "L Sánchez Agudo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2002" "volumen" => "38" "paginaInicial" => "351" "paginaFinal" => "355" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12199915" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Abuse liability and pharmacodynamic characteristics of intravenous and inhaled nicotine" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "JE Henningfield" 1 => "K Miyasato" 2 => "DR Jasinski" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Pharmacol Exp Ther" "fecha" => "1985" "volumen" => "234" "paginaInicial" => "1" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4009494" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacokinetic considerations in understanding nicotine dependence" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "NL Benowitz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Ciba Found Symp" "fecha" => "1990" "volumen" => "152" "paginaInicial" => "186" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2209254" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib32" "etiqueta" => "32" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "American Psychiatric Association" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Diagnostic and statistical manual of mental disorders" "fecha" => "1994" "editorial" => "American Psychiatric Association" "editorialLocalizacion" => "Washington DC" ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib33" "etiqueta" => "33" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "MC Fine" 1 => "WC Bailey" 2 => "SJ Cohen" 3 => "S Dorfman" 4 => "MG Goldstein" 5 => "ER Gritz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Treating tobacco use and dependence. Clinical practice guideline" "fecha" => "2000" "editorial" => "US Department of Health and Human Services. Public Health Service" "editorialLocalizacion" => "Rockville, MD" ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib34" "etiqueta" => "34" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The safety of transdermal nicotine as an aid to smoking cessation in patients with cardiac disease" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "AM Joseph" 1 => "SM Norman" 2 => "LH Ferry" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "N Engl J Med" "fecha" => "1996" "volumen" => "335" "paginaInicial" => "1792" ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib35" "etiqueta" => "35" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nicotine replacement therapy for patients with coronary artery disease" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Working Group for the Study of Transdermal Nicotine in Patients with Coronary Artery Disease" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Intern Med" "fecha" => "1994" "volumen" => "154" "paginaInicial" => "989" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8179456" "web" => "Medline" ] ] ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib36" "etiqueta" => "36" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Safety of nicotine polacrilex gum used by 3,094 participants in the Lung Health Study. Lung Health Study Research Group" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "RP Murray" 1 => "WC Bailey" 2 => "K Daniels" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Chest" "fecha" => "1996" "volumen" => "109" "paginaInicial" => "438" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8620719" "web" => "Medline" ] ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib37" "etiqueta" => "37" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk of acute first myocardial infarction and use of nicotine patches in a general population" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "SE Kimmel" 1 => "JA Berlin" 2 => "C Miles" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2001" "volumen" => "37" "paginaInicial" => "1297" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11300438" "web" => "Medline" ] ] ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib38" "etiqueta" => "38" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nicotine replacement therapy during pregnancy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "NL Benowitz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "JAMA" "fecha" => "1991" "volumen" => "166" "paginaInicial" => "3174" "paginaFinal" => "3177" ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib39" "etiqueta" => "39" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nicotine patches for pregnant smokers. A randomised controlled study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R Wisberg" 1 => "T Hensikan" 2 => "N Jespersen Ljorgen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Obstet Gynecol" "fecha" => "2000" "volumen" => "96" "paginaInicial" => "967" "paginaFinal" => "971" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11084187" "web" => "Medline" ] ] ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib40" "etiqueta" => "40" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Aiding reduction of smoking with nicotine replacement medications. Hope for the recalcitrant smokers?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "KO Fagerström" 1 => "R Tejding" 2 => "A Westin" 3 => "E Lunell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Tobacco Control" "fecha" => "1997" "volumen" => "6" "paginaInicial" => "311" "paginaFinal" => "316" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9583629" "web" => "Medline" ] ] ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib41" "etiqueta" => "41" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High dose nicotine patch therapy: percentage of replacement and smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "L Dale" 1 => "R Hurt" 2 => "K Offord" 3 => "G Lawson" 4 => "I Croghan" 5 => "D Shroeder" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "JAMA" "fecha" => "1995" "volumen" => "274" "paginaInicial" => "1353" "paginaFinal" => "1358" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7563559" "web" => "Medline" ] ] ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib42" "etiqueta" => "42" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Any further progress in smoking cessation treatment?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T Piasecki" 1 => "T Baker" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1080/14622200110050484" "Revista" => array:5 [ "tituloSerie" => "Nicotine Tob Res" "fecha" => "2001" "volumen" => "3" "paginaInicial" => "311" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11694198" "web" => "Medline" ] ] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib43" "etiqueta" => "43" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Combined use of nicotine replacement products" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "KO Fagerström" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Health Values" "fecha" => "1994" "volumen" => "18" "paginaInicial" => "15" "paginaFinal" => "20" ] ] ] ] ] ] 43 => array:3 [ "identificador" => "bib45" "etiqueta" => "45" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Randomized comparative trial of nicotine polacrilex, a transdermal patch, nasal spray, and an inhaler" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ 0 => "P Hajek" 1 => "R West" 2 => "J Foulds" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Intern Med" "fecha" => "1999" "volumen" => "159" "paginaInicial" => "2033" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10510989" "web" => "Medline" ] ] ] ] ] ] ] ] 44 => array:3 [ "identificador" => "bib46" "etiqueta" => "46" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effectiveness of interventions to help people stop smoking: findings from the Cochrane library" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T Lancaster" 1 => "L Stead" 2 => "C Silagy" 3 => "A Sowden" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "BMJ" "fecha" => "2000" "volumen" => "321" "paginaInicial" => "355" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10926597" "web" => "Medline" ] ] ] ] ] ] ] ] 45 => array:3 [ "identificador" => "bib47" "etiqueta" => "47" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Contolled trial of nicotine polacrilex gum with supportive measures" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "T Blondal" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Intern Med" "fecha" => "1989" "volumen" => "149" "paginaInicial" => "1818" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2669665" …1 ] ] ] ] ] ] ] ] 46 => array:3 [ "identificador" => "bib48" "etiqueta" => "48" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Smoking cessation in highly dependent smokers with 4 mg nicotine polacrilex" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Am J Health Behavior" "fecha" => "1996" "volumen" => "20" "paginaInicial" => "319" ] ] ] ] ] ] 47 => array:3 [ "identificador" => "bib49" "etiqueta" => "49" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ …5] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Nicotine replacement therapy for smoking cessation (Cochrane database of systematic reviews). The Cochrane Library" "fecha" => "2003" "editorial" => "Update Software" "editorialLocalizacion" => "Oxford" ] ] ] ] ] ] 48 => array:3 [ "identificador" => "bib50" "etiqueta" => "50" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Signs and symptoms of tobacco withdrawal" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Gen Psychiatry" "fecha" => "1986" "volumen" => "43" "paginaInicial" => "289" "paginaFinal" => "294" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 49 => array:3 [ "identificador" => "bib51" "etiqueta" => "51" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Two and four mg nicotine chewing gum and group counselling in smoking cessation: an open, randomised controlled trial with a 22 month follow-up" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Addict Behav" "fecha" => "1988" "volumen" => "13" "paginaInicial" => "17" "paginaFinal" => "27" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 50 => array:3 [ "identificador" => "bib52" "etiqueta" => "52" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nicotine gum, 2 and 4 mg, for nicotine dependence. A double blind placebo controlled trial within a behavior modification support program" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Chest" "fecha" => "1995" "volumen" => "108" "paginaInicial" => "447" "paginaFinal" => "451" ] ] ] ] ] ] 51 => array:3 [ "identificador" => "bib53" "etiqueta" => "53" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A double blind study of 2 mg versus 4 mg nicotine gum in an industrial setting" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Psychosom Res" "fecha" => "1987" "volumen" => "31" "paginaInicial" => "171" "paginaFinal" => "176" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 52 => array:3 [ "identificador" => "bib54" "etiqueta" => "54" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Meta-analysis of randomised controlled trials of nicotine chewing-gum" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Lancet" "fecha" => "1987" "volumen" => "2" "paginaInicial" => "27" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 53 => array:3 [ "identificador" => "bib55" "etiqueta" => "55" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Pharmacia and Upjohn. Summary of product characteristic for nicorette sublingual tablet 2 mg. 1998." ] ] ] 54 => array:3 [ "identificador" => "bib56" "etiqueta" => "56" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of a nicotine lozenge for smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Intern Med" "fecha" => "2002" "volumen" => "162" "paginaInicial" => "1267" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 55 => array:3 [ "identificador" => "bib57" "etiqueta" => "57" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tobacco dependence and the nicotine patch. Clinical guidelines for effective use" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "JAMA" "fecha" => "1992" "volumen" => "268" "paginaInicial" => "2687" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 56 => array:3 [ "identificador" => "bib58" "etiqueta" => "58" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transdermal nicotine for smoking cessation. Six-month results from two multicenter controlled clinical trials" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Transdermal Nicotine Study Group" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "JAMA" "fecha" => "1991" "volumen" => "266" "paginaInicial" => "3133" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 57 => array:3 [ "identificador" => "bib59" "etiqueta" => "59" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nicotine gum, 2 and 4 mg, for nicotine dependence. A double-blind placebo-controlled trial within a behavior modification support program" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Chest" "fecha" => "1995" "volumen" => "108" "paginaInicial" => "447" "paginaFinal" => "451" ] ] ] ] ] ] 58 => array:3 [ "identificador" => "bib60" "etiqueta" => "60" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Combined use of nicotine patch and gum compared with gum alone in smoking cessation: a clinical trial in North Karelia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Tob Control" "fecha" => "1995" "volumen" => "4" "paginaInicial" => "231" "paginaFinal" => "235" ] ] ] ] ] ] 59 => array:3 [ "identificador" => "bib61" "etiqueta" => "61" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of fixed-dose transdermal nicotine, tapered dose transdermal nicotine, and buspirone in smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Pharmacol" "fecha" => "1994" "volumen" => "34" "paginaInicial" => "222" "paginaFinal" => "224" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 60 => array:3 [ "identificador" => "bib62" "etiqueta" => "62" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Targeting heavy smokers in general practice: randomised controlled trial of transdermal nicotine patches" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "BMJ" "fecha" => "1993" "volumen" => "306" "paginaInicial" => "1308" "paginaFinal" => "1312" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 61 => array:3 [ "identificador" => "bib63" "etiqueta" => "63" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparative efficacy of 24 hour and 16 hour transdermal nicotine patches for relief of morning craving" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Addiction" "fecha" => "2000" "volumen" => "95" "paginaInicial" => "1185" "paginaFinal" => "1195" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 62 => array:3 [ "identificador" => "bib64" "etiqueta" => "64" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Three year continuous abstinence in a smoking cessation study using the nicotine transdermal patch" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Heart" "fecha" => "1997" "volumen" => "78" "paginaInicial" => "617" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 63 => array:3 [ "identificador" => "bib65" "etiqueta" => "65" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The smoking cessation efficacy of varying doses of nicotine patch delivery systems 4 to 5 years post-quit day" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1006/pmed.1998.0391" "Revista" => array:5 [ "tituloSerie" => "Prev Med" "fecha" => "1999" "volumen" => "28" "paginaInicial" => "113" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 64 => array:3 [ "identificador" => "bib66" "etiqueta" => "66" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Are higher doses of nicotine replacement more effective for smoking cessation?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Nicotine Tob Res" "fecha" => "1999" "volumen" => "1" "paginaInicial" => "169" "paginaFinal" => "174" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 65 => array:3 [ "identificador" => "bib67" "etiqueta" => "67" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High-dose nicotine patch therapy – percentage of replacement and smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "JAMA" "fecha" => "1995" "volumen" => "274" "paginaInicial" => "1353" "paginaFinal" => "1358" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 66 => array:3 [ "identificador" => "bib68" "etiqueta" => "68" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Varying nicotine patch dose and type of smoking cessation counselling" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "JAMA" "fecha" => "1995" "volumen" => "274" "paginaInicial" => "1347" "paginaFinal" => "1352" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 67 => array:3 [ "identificador" => "bib69" "etiqueta" => "69" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Higher dosage nicotine patches increase one year smoking cessation rates. Results from the European CEASE trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1999" "volumen" => "13" "paginaInicial" => "238" "paginaFinal" => "246" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 68 => array:3 [ "identificador" => "bib70" "etiqueta" => "70" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Do heavy smokers benefit from higher dose nicotine patch therapy?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ …5] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Exp Clin Psychopharmacol" "fecha" => "1999" "volumen" => "7226" "paginaInicial" => "233" ] ] ] ] ] ] 69 => array:3 [ "identificador" => "bib71" "etiqueta" => "71" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Importance of baseline cotinine plasma values in smoking cessation: results from a double blind study with nicotine patch" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1996" "volumen" => "9" "paginaInicial" => "643" "paginaFinal" => "651" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 70 => array:3 [ "identificador" => "bib72" "etiqueta" => "72" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recent advances in the pharmacotherapy of smoking" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "JAMA" "fecha" => "1999" "volumen" => "281" "paginaInicial" => "72" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 71 => array:3 [ "identificador" => "bib73" "etiqueta" => "73" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Physician's Desk Reference 1998" "fecha" => "1998" "editorial" => "Medical Economics" "editorialLocalizacion" => "Montvale, NJ" ] ] ] ] ] ] 72 => array:3 [ "identificador" => "bib74" "etiqueta" => "74" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "How much does relapse after one year erode effectivenes of smoking cessation treatments? Long term follow up randomised trial of nicotine nasal spray" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br Med J" "fecha" => "1998" "volumen" => "316" "paginaInicial" => "830" "paginaFinal" => "831" ] ] ] ] ] ] 73 => array:3 [ "identificador" => "bib75" "etiqueta" => "75" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tratamiento del tabaquismo con nebulizador nasal de nicotina. Resultados de un estudio multicéntrico" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1999" "volumen" => "35" "paginaInicial" => "535" "paginaFinal" => "538" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 74 => array:3 [ "identificador" => "bib76" "etiqueta" => "76" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Concurrent agonist-antagonist administration for the analysis and treatment of drug dependence" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pharmacol Biochem Behav" "fecha" => "1991" "volumen" => "41" "paginaInicial" => "219" "paginaFinal" => "226" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 75 => array:3 [ "identificador" => "bib77" "etiqueta" => "77" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of the nicotine inhaler as an adjunct to smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Health Behav" "fecha" => "1996" "volumen" => "20" "paginaInicial" => "364" "paginaFinal" => "371" ] ] ] ] ] ] 76 => array:3 [ "identificador" => "bib78" "etiqueta" => "78" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Efficacy of nicotine inhaler in smoking cessation: a double blind placebo controlled trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Addiction" "fecha" => "1996" "volumen" => "91" "paginaInicial" => "1293" "paginaFinal" => "1306" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 77 => array:3 [ "identificador" => "bib79" "etiqueta" => "79" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioural and cardiovascular effects in rats" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Pharmacol Biochem Beha" "fecha" => "2000" "volumen" => "65" "paginaInicial" => "191" "paginaFinal" => "198" ] ] ] ] ] ] 78 => array:3 [ "identificador" => "bib80" "etiqueta" => "80" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Active immunization against nicotine suppresses nicotine-induced dopamine release in the rat nucleus accumbens shell" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "63628" "Revista" => array:6 [ "tituloSerie" => "Respiration" "fecha" => "2002" "volumen" => "69" "paginaInicial" => "247" "paginaFinal" => "253" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 79 => array:3 [ "identificador" => "bib81" "etiqueta" => "81" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Active immunization against nicotine prevents reinstatement of nicotine-seeking behavior in rats" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "63629" "Revista" => array:6 [ "tituloSerie" => "Respiration" "fecha" => "2002" "volumen" => "69" "paginaInicial" => "254" "paginaFinal" => "260" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 80 => array:3 [ "identificador" => "bib82" "etiqueta" => "82" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Metabolism of nicotine to cotinine studied by a dual stable isotope method" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Pharmacol Ther" "fecha" => "1994" "volumen" => "56" "paginaInicial" => "483" "paginaFinal" => "493" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 81 => array:3 [ "identificador" => "bib83" "etiqueta" => "83" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CYP2A6 genetic variation and potential consequences" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Adv Drug Deliv Rev" "fecha" => "2002" "volumen" => "54" "paginaInicial" => "1245" "paginaFinal" => "1256" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 82 => array:3 [ "identificador" => "bib84" "etiqueta" => "84" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Duplications and defects in the CYP2A6 gene: identification, genotyping, and in vivo effects on smoking" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Mol Pharmacol" "fecha" => "2000" "volumen" => "58" "paginaInicial" => "747" "paginaFinal" => "755" ] ] ] ] ] ] 83 => array:3 [ "identificador" => "bib85" "etiqueta" => "85" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Decreasing smoking behaviour and risk through CYP2A6 inhibition" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Drug Discov Today" "fecha" => "2003" "volumen" => "8" "paginaInicial" => "487" "paginaFinal" => "493" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 84 => array:3 [ "identificador" => "bib86" "etiqueta" => "86" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The use of long PCR to confirm three common alleles at the CYP2A6 locus and the relationship between genotype and smoking habit" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am Hum Genet." "fecha" => "2000" "volumen" => "64" "paginaInicial" => "383" "paginaFinal" => "390" ] ] ] ] ] ] 85 => array:3 [ "identificador" => "bib87" "etiqueta" => "87" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inhibition of cytochrome P450 2A6 increases nicotine's oral bioavailability and decreases smoking" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mcp.2000.107651" "Revista" => array:6 [ "tituloSerie" => "Clin Pharmacol Ther" "fecha" => "2000" "volumen" => "68" "paginaInicial" => "35" "paginaFinal" => "43" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 86 => array:3 [ "identificador" => "bib88" "etiqueta" => "88" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of ephedrine plus caffeine on smoking cessation and postcessation weight gain" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0009-9236(96)90217-9" "Revista" => array:6 [ "tituloSerie" => "Clin Pharmacol Ther" "fecha" => "1996" "volumen" => "60" "paginaInicial" => "679" "paginaFinal" => "686" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 87 => array:3 [ "identificador" => "bib89" "etiqueta" => "89" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is clonidine an effective smoking cessation therapy?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Drugs" "fecha" => "1995" "volumen" => "50" "paginaInicial" => "197" "paginaFinal" => "207" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 88 => array:3 [ "identificador" => "bib90" "etiqueta" => "90" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An analysis of the effectiveness of interventions intended to help people stop smoking" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Intern Med" "fecha" => "1995" "volumen" => "155" "paginaInicial" => "1933" "paginaFinal" => "1941" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 89 => array:3 [ "identificador" => "bib91" "etiqueta" => "91" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A meta-analysis of double-blind placebo-controlled trials of clonidine for smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Addict" "fecha" => "1991" "volumen" => "86" "paginaInicial" => "991" "paginaFinal" => "998" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 90 => array:3 [ "identificador" => "bib92" "etiqueta" => "92" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Clinical practice guideline smoking cessation" "fecha" => "1996" "editorial" => "US Government Printing Office" "editorialLocalizacion" => "Washington, DC" ] ] ] ] ] ] 91 => array:3 [ "identificador" => "bib93" "etiqueta" => "93" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Naltrexone, smoking behavior and cigarette withdrawal" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ …4] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Psycopharmacology" "fecha" => "1995" "volumen" => "120" "paginaInicial" => "418" "paginaFinal" => "425" ] ] ] ] ] ] 92 => array:3 [ "identificador" => "bib94" "etiqueta" => "94" "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Humfleet G, Hall S, Reus V, Sees K, Muñoz R, Triffleman E. The efficacy of nortriptyline as an adjunct to psychological treatment for smokers with and without depression histories. In: Harris LS, editor. Problems of drug dependence 1995: Proceedings of the 57th Annual Scientific Meeting of the College on Problems of drug dependence, Inc. NDA Research monograph 162. Washington, DC: Government Printing Office, 1996; 334 abstract. (DHHS publication n. [ADM] 96-41116.)" ] ] ] 93 => array:3 [ "identificador" => "bib95" "etiqueta" => "95" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of doxepin on withdrawal symptoms in smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1176/ajp.147.10.1353" "Revista" => array:6 [ "tituloSerie" => "Am J Psychiatry" "fecha" => "1990" "volumen" => "147" "paginaInicial" => "1353" "paginaFinal" => "1357" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 94 => array:3 [ "identificador" => "bib96" "etiqueta" => "96" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Doxepin in the treatment of nicotine withdrawal" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Psychosomatic" "fecha" => "1988" "volumen" => "29" "paginaInicial" => "203" "paginaFinal" => "206" ] ] ] ] ] ] 95 => array:3 [ "identificador" => "bib97" "etiqueta" => "97" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Non nicotine pharmacotherapies for smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Drug Dev" "fecha" => "1994" "volumen" => "6" "paginaInicial" => "197" "paginaFinal" => "203" ] ] ] ] ] ] 96 => array:3 [ "identificador" => "bib98" "etiqueta" => "98" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inhibition of monoamine oxidase B in the brains of smokers" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/379733a0" "Revista" => array:6 [ "tituloSerie" => "Nature" "fecha" => "1996" "volumen" => "379" "paginaInicial" => "733" "paginaFinal" => "737" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 97 => array:3 [ "identificador" => "bib99" "etiqueta" => "99" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A preliminary placebo-controlled trial of selegiline hydrochloride for smoking cessation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Biol Psychiatry" "fecha" => "2003" "volumen" => "53" "paginaInicial" => "136" "paginaFinal" => "143" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 98 => array:3 [ "identificador" => "bib100" "etiqueta" => "100" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A reversible monoamine oxidase A inhibitor (moclobemide) facilitates smoking cessation and abstinence in heavy dependent smokers" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/0009-9236(95)90058-6" "Revista" => array:6 [ "tituloSerie" => "Clin Pharmacol Ther" "fecha" => "1995" "volumen" => "58" "paginaInicial" => "444" "paginaFinal" => "452" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 99 => array:3 [ "identificador" => "bib101" "etiqueta" => "101" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antidepressant pharmacotherapy helps some cigarette smokers more than others" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Consult Clin Psychol" "fecha" => "1999" "volumen" => "67" "paginaInicial" => "547" "paginaFinal" => "554" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 100 => array:3 [ "identificador" => "bib102" "etiqueta" => "102" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A placebo-controlled evaluation of the effects of buspirone on smoking cessation: differences between high and low anxiety smokers" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ …6] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Psychopharmacol" "fecha" => "1995" "volumen" => "15" "paginaInicial" => "182" "paginaFinal" => "191" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 101 => array:3 [ "identificador" => "bib103" "etiqueta" => "103" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inhalation of vapor from black peper extract reduces smoking withdrawal symptoms" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ …2] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Drug Alcohol Depend" "fecha" => "1994" "volumen" => "34" "paginaInicial" => "225" "paginaFinal" => "229" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] 102 => array:3 [ "identificador" => "bib104" "etiqueta" => "104" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Silver acetate gum as a smoking deterrent" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ …1] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Chest" "fecha" => "1986" "volumen" => "89" "paginaInicial" => "107" "paginaFinal" => "111" ] ] ] ] ] ] 103 => array:3 [ "identificador" => "bib105" "etiqueta" => "105" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High-frequency repetitive transcranial magnetic stimulation decreases cigarette smoking" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ …3] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Psychiatry" "fecha" => "2003" "volumen" => "64" "paginaInicial" => "951" "paginaFinal" => "953" "link" => array:1 [ 0 => array:2 [ …2] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000004000000003/v1_201305141830/S1579212906700775/v1_201305141830/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004000000003/v1_201305141830/S1579212906700775/v1_201305141830/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212906700775?idApp=UINPBA00003Z" ]
Year/Month | Html | Total | |
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2024 November | 3 | 3 | 6 |
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2024 August | 45 | 38 | 83 |
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2024 April | 18 | 18 | 36 |
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2022 December | 19 | 34 | 53 |
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2022 October | 18 | 24 | 42 |
2022 September | 10 | 23 | 33 |
2022 August | 17 | 43 | 60 |
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2022 June | 15 | 36 | 51 |
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2022 April | 14 | 24 | 38 |
2022 March | 17 | 35 | 52 |
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2021 December | 17 | 40 | 57 |
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2020 December | 10 | 13 | 23 |
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2020 May | 16 | 15 | 31 |
2020 April | 19 | 15 | 34 |
2020 March | 19 | 11 | 30 |
2020 February | 14 | 16 | 30 |
2020 January | 16 | 11 | 27 |
2019 December | 20 | 18 | 38 |
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2019 October | 8 | 8 | 16 |
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2019 July | 21 | 18 | 39 |
2019 June | 8 | 5 | 13 |
2019 May | 11 | 18 | 29 |
2019 April | 31 | 23 | 54 |
2019 March | 12 | 19 | 31 |
2019 February | 8 | 10 | 18 |
2019 January | 10 | 8 | 18 |
2018 December | 7 | 9 | 16 |
2018 November | 9 | 6 | 15 |
2018 October | 8 | 9 | 17 |
2018 September | 8 | 11 | 19 |
2018 May | 1 | 1 | 2 |
2018 April | 5 | 5 | 10 |
2018 March | 4 | 8 | 12 |
2018 February | 3 | 8 | 11 |
2018 January | 5 | 7 | 12 |
2017 December | 3 | 4 | 7 |
2017 November | 2 | 11 | 13 |
2017 October | 4 | 9 | 13 |
2017 September | 3 | 8 | 11 |
2017 August | 11 | 10 | 21 |
2017 July | 3 | 8 | 11 |
2017 June | 6 | 12 | 18 |
2017 May | 8 | 5 | 13 |
2017 April | 9 | 11 | 20 |
2017 March | 16 | 13 | 29 |
2017 February | 7 | 2 | 9 |
2017 January | 2 | 3 | 5 |
2016 December | 8 | 5 | 13 |
2016 November | 14 | 7 | 21 |
2016 October | 16 | 14 | 30 |
2016 September | 9 | 6 | 15 |
2016 August | 11 | 4 | 15 |
2016 July | 4 | 3 | 7 |
2016 March | 3 | 0 | 3 |
2015 December | 3 | 0 | 3 |
2015 October | 44 | 1 | 45 |
2015 September | 62 | 5 | 67 |
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2015 July | 51 | 5 | 56 |
2015 June | 29 | 6 | 35 |
2015 May | 49 | 5 | 54 |
2015 April | 19 | 8 | 27 |
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2014 December | 19 | 5 | 24 |
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2014 October | 32 | 9 | 41 |
2014 September | 25 | 6 | 31 |
2014 August | 27 | 11 | 38 |
2014 July | 20 | 5 | 25 |
2014 June | 37 | 9 | 46 |
2014 May | 30 | 9 | 39 |
2014 April | 36 | 4 | 40 |
2014 March | 39 | 9 | 48 |
2014 February | 34 | 5 | 39 |
2014 January | 22 | 5 | 27 |
2013 December | 27 | 9 | 36 |
2013 November | 18 | 5 | 23 |
2013 October | 30 | 8 | 38 |
2013 September | 31 | 12 | 43 |
2013 August | 36 | 9 | 45 |
2013 July | 43 | 13 | 56 |
2013 June | 30 | 4 | 34 |
2013 May | 36 | 6 | 42 |
2013 April | 12 | 4 | 16 |
2013 March | 6 | 1 | 7 |