Correspondence: Dr. J. Padilla Alarcón. Servicio de Cirugía Torácica. Hospital Universitario La Fe. Avda. de Campanar, 21. 46009 Valencia. España
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Díaz Sánchez, A. López Viña" "autores" => array:2 [ 0 => array:3 [ "preGrado" => "Dra" "nombre" => "C." "apellidos" => "Díaz Sánchez" ] 1 => array:2 [ "nombre" => "A." 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Giner, M. Torrejón, A. Ramos, P. Casan, C. Granel, V. Plaza, J. Belda, J. Sanchis" "autores" => array:8 [ 0 => array:3 [ "preGrado" => "Dr" "nombre" => "J." "apellidos" => "Giner" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Torrejón" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Ramos" ] 3 => array:2 [ "nombre" => "P." "apellidos" => "Casan" ] 4 => array:2 [ "nombre" => "C." "apellidos" => "Granel" ] 5 => array:2 [ "nombre" => "V." "apellidos" => "Plaza" ] 6 => array:2 [ "nombre" => "J." "apellidos" => "Belda" ] 7 => array:2 [ "nombre" => "J." "apellidos" => "Sanchis" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921290670074X?idApp=UINPBA00003Z" "url" => "/15792129/0000004000000003/v1_201305141830/S157921290670074X/v1_201305141830/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Stage I Nonsmall Cell Lung Cancer up to 3 cm in Diameter: Prognostic Factors" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "110" "paginaFinal" => "113" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J. Padilla, V. Calvo, J.C. Peñalver, C. Jordá, J. Escrivá, A. García Zarza, J. Pastor, E. Blasco" "autores" => array:8 [ 0 => array:5 [ "preGrado" => "Dr" "nombre" => "J." "apellidos" => "Padilla" "email" => array:1 [ 0 => "jpadilla@comv.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:2 [ "nombre" => "V." "apellidos" => "Calvo" ] 2 => array:2 [ "nombre" => "J.C." "apellidos" => "Peñalver" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Jordá" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Escrivá" ] 5 => array:2 [ "nombre" => "A." "apellidos" => "García Zarza" ] 6 => array:2 [ "nombre" => "J." "apellidos" => "Pastor" ] 7 => array:2 [ "nombre" => "E." "apellidos" => "Blasco" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Cirugía Torácica, Hospital Universitario La Fe, Valencia, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. J. Padilla Alarcón. Servicio de Cirugía Torácica. Hospital Universitario La Fe. Avda. de Campanar, 21. 46009 Valencia. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2003-08-01" "fechaAceptado" => "2003-09-13" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec153309" "palabras" => array:5 [ 0 => "Nonsmall cell lung cancer" 1 => "Stage I" 2 => "Surgery" 3 => "Time trend" 4 => "Tumor size" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec153308" "palabras" => array:5 [ 0 => "Carcinoma broncogénico" 1 => "Estadio I" 2 => "Cirugía" 3 => "Tendencia temporal" 4 => "Tamaño" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO assess the prognostic value of a series of clinicopathological variables in stage I nonsmall cell lung cancer, for tumors up to 3 cm in diameter.</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p class="elsevierStyleSimplePara elsevierViewall">The study included 271 patients. Survival was analyzed with the Kaplan-Meier method. The Cox model was used for multivariate analysis.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Five- and ten-year survival were 78.63% and 67.59%, respectively. Survival did not significantly depend on sex, age, extent of resection, histology, visceral pleural invasion, level of bronchial invasion or T1 versus T2. The decade in which resection was performed did affect survival (<span class="elsevierStyleItalic">P</span>=.0037). Five-year survival was 58% for operations between 1970 and 1980, 77% for operations between 1981 and 1990, and 84% for operations between 1991 and 2000. Tumor size also affected survival (<span class="elsevierStyleItalic">P</span>=.0046), which was 86% for patients with tumors of less than or equal to 2 cm in diameter and 73% for those with tumors of more than 2 cm in diameter. In the multivariate analysis both variables entered into regression, remaining predictive of survival.</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p class="elsevierStyleSimplePara elsevierViewall">We found evidence for a prognostic stage migration (Will Rogers phenomenon) according to the decade in which resection was performed and that tumor size affected survival in our population. Finally, the current system of TNM staging fails in conforming groups of patients with a homogenous prognosis.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Valorar el papel pronóstico de una serie de variables clínico-patológicas en el carcinoma broncogénico no anaplásico de células pequeñas con un tamaño máximo de 3 cm y clasificado en estadio I.</p> <span class="elsevierStyleSectionTitle">Pacientes Y Método</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudió a 271 pacientes. La supervivencia se analizó con el método de Kaplan-Meier. Para el análisis multivariante se utilizó el modelo de Cox.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">La supervivencia fue del 78,63 y el 67,59% a los 5 y 10 años, respectivamente. El sexo, la edad, la amplitud de exéresis, la estirpe histológica, la invasión de la pleura visceral, el grado de invasión bronquial y T1-T2 no influyeron significativamente en la supervivencia. La década en que el paciente fue operado condicionó la supervivencia (p = 0,0037), que a los 5 años fue del 58% para los intervenidos entre 1970 y 1980, del 77% para los operados entre 1981 y 1990 y del 84% para los sometidos a la intervención entre 1991 y 2000. El tamaño tumoral también condicionó la supervivencia (p = 0,0046), que fue del 86% para los pacientes con tumores con un diámetro inferior o igual a 2 cm y del 73% para los que tenían tumores con diámetro de más de 2 cm. Ambas variables entraron en regresión cuando se utilizó el análisis multivariante.</p> <span class="elsevierStyleSectionTitle">Conclusión</span><p class="elsevierStyleSimplePara elsevierViewall">Hemos comprobado una migración pronóstica (fenómeno de Will Rogers) en relación con la década en que el paciente fue operado (<span class="elsevierStyleItalic">time trend</span>) y que el tamaño tumoral condicionó la supervivencia de nuestra serie. Por último, el sistema vigente de estadificación TNM es deficiente en la configuración de grupos de pacientes con un pronóstico homogéneo.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:29 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnóstico precoz del cáncer de pulmón" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L Callol Sánchez" 1 => "Gómez de Terreros" 2 => "FJ Sánchez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1999" "volumen" => "35" "paginaInicial" => "395" "paginaFinal" => "403" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10548986" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S095461111000380X" "estado" => "S300" "issn" => "09546111" ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "¿Es el momento de plantear la detección precoz del carcinoma broncogénico en la Comunidad Autónoma de Madrid?" 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Year/Month | Html | Total | |
---|---|---|---|
2024 November | 3 | 3 | 6 |
2024 October | 20 | 10 | 30 |
2024 September | 22 | 10 | 32 |
2024 August | 44 | 26 | 70 |
2024 July | 26 | 17 | 43 |
2024 June | 25 | 13 | 38 |
2024 May | 30 | 20 | 50 |
2024 April | 15 | 15 | 30 |
2024 March | 19 | 12 | 31 |
2024 February | 15 | 14 | 29 |
2023 March | 3 | 3 | 6 |
2023 February | 15 | 27 | 42 |
2023 January | 14 | 30 | 44 |
2022 December | 14 | 27 | 41 |
2022 November | 15 | 23 | 38 |
2022 October | 17 | 24 | 41 |
2022 September | 15 | 23 | 38 |
2022 August | 12 | 35 | 47 |
2022 July | 14 | 32 | 46 |
2022 June | 14 | 27 | 41 |
2022 May | 16 | 38 | 54 |
2022 April | 15 | 21 | 36 |
2022 March | 22 | 33 | 55 |
2022 February | 16 | 27 | 43 |
2022 January | 20 | 35 | 55 |
2021 December | 20 | 46 | 66 |
2021 November | 24 | 45 | 69 |
2021 October | 26 | 39 | 65 |
2021 September | 21 | 52 | 73 |
2021 August | 18 | 29 | 47 |
2021 July | 11 | 20 | 31 |
2021 June | 17 | 35 | 52 |
2021 May | 10 | 19 | 29 |
2021 April | 41 | 59 | 100 |
2021 March | 11 | 34 | 45 |
2021 February | 14 | 13 | 27 |
2021 January | 10 | 4 | 14 |
2020 December | 12 | 13 | 25 |
2020 November | 5 | 15 | 20 |
2020 October | 10 | 11 | 21 |
2020 September | 7 | 5 | 12 |
2020 August | 8 | 15 | 23 |
2020 July | 13 | 15 | 28 |
2020 June | 6 | 11 | 17 |
2020 May | 17 | 21 | 38 |
2020 April | 16 | 9 | 25 |
2020 March | 11 | 12 | 23 |
2020 February | 11 | 24 | 35 |
2020 January | 13 | 15 | 28 |
2019 December | 16 | 14 | 30 |
2019 November | 11 | 11 | 22 |
2019 October | 5 | 11 | 16 |
2019 September | 3 | 13 | 16 |
2019 August | 13 | 12 | 25 |
2019 July | 10 | 11 | 21 |
2019 June | 3 | 8 | 11 |
2019 May | 10 | 8 | 18 |
2019 April | 19 | 20 | 39 |
2019 March | 12 | 13 | 25 |
2019 February | 9 | 10 | 19 |
2019 January | 1 | 1 | 2 |
2018 December | 5 | 14 | 19 |
2018 November | 4 | 4 | 8 |
2018 October | 14 | 13 | 27 |
2018 September | 10 | 8 | 18 |
2018 May | 3 | 0 | 3 |
2018 April | 7 | 4 | 11 |
2018 March | 9 | 3 | 12 |
2018 February | 2 | 7 | 9 |
2018 January | 5 | 9 | 14 |
2017 December | 4 | 6 | 10 |
2017 November | 3 | 5 | 8 |
2017 October | 7 | 9 | 16 |
2017 September | 5 | 7 | 12 |
2017 August | 9 | 13 | 22 |
2017 July | 4 | 5 | 9 |
2017 June | 8 | 28 | 36 |
2017 May | 8 | 9 | 17 |
2017 April | 4 | 2 | 6 |
2017 March | 1 | 2 | 3 |
2017 February | 1 | 4 | 5 |
2017 January | 3 | 3 | 6 |
2016 December | 6 | 5 | 11 |
2016 November | 15 | 8 | 23 |
2016 October | 11 | 9 | 20 |
2016 September | 11 | 4 | 15 |
2016 August | 7 | 5 | 12 |
2016 July | 2 | 4 | 6 |
2016 June | 1 | 0 | 1 |
2016 March | 1 | 0 | 1 |
2016 February | 1 | 0 | 1 |
2015 December | 3 | 0 | 3 |
2015 October | 34 | 1 | 35 |
2015 September | 35 | 9 | 44 |
2015 August | 45 | 9 | 54 |
2015 July | 41 | 5 | 46 |
2015 June | 38 | 4 | 42 |
2015 May | 51 | 11 | 62 |
2015 April | 42 | 16 | 58 |
2015 March | 23 | 9 | 32 |
2015 February | 14 | 1 | 15 |
2015 January | 21 | 7 | 28 |
2014 December | 25 | 4 | 29 |
2014 November | 30 | 6 | 36 |
2014 October | 41 | 11 | 52 |
2014 September | 31 | 6 | 37 |
2014 August | 28 | 8 | 36 |
2014 July | 27 | 7 | 34 |
2014 June | 61 | 13 | 74 |
2014 May | 41 | 5 | 46 |
2014 April | 37 | 3 | 40 |
2014 March | 40 | 5 | 45 |
2014 February | 32 | 14 | 46 |
2014 January | 27 | 7 | 34 |
2013 December | 41 | 8 | 49 |
2013 November | 19 | 5 | 24 |
2013 October | 31 | 3 | 34 |
2013 September | 41 | 12 | 53 |
2013 August | 33 | 14 | 47 |
2013 July | 47 | 12 | 59 |
2013 June | 27 | 9 | 36 |
2013 May | 32 | 10 | 42 |
2013 April | 23 | 5 | 28 |
2013 March | 10 | 2 | 12 |