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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO analyze in-hospital and 2-year survival of patients who require mechanical ventilation with intubation after acute respiratory failure due to exacerbation of chronic obstructive pulmonary disease &#40;COPD&#41;&#46; The secondary objective was to identify the prognostic factors for in-hospital mortality and mortality at 2 years&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We retrospectively studied 101 patients with suspected COPD admitted to the intensive care unit between July 1993 and December 1998&#46; Variables potentially related to mortality were analyzed with a univariate model and by logistic regression&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">In-hospital survival was 74&#46;3&#37; and 2-year survival was 55&#46;4&#37;&#46; Survival at 2 years was 81&#37; for patients discharged from hospital&#46; The variables associated with in-hospital mortality were age greater than 65 years&#44; electrocardiographic diagnosis of chronic cor pulmonale&#44; and development of multiorgan dysfunction syndrome&#46; No factors predictive of mortality at 2 years were identified&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The in-hospital survival rate for patients with an acute exacerbation of COPD who require mechanical ventilation is good and the 2-year survival rate is acceptable&#46; Age&#44; electrocardiographic signs of cor pulmonale&#44; and development of multiorgan dysfunction syndrome were associated with greater risk of in-hospital mortality&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Analizar la supervivencia hospitalaria y a los 2 a&#241;os de los pacientes con insuficiencia respiratoria aguda&#44; debida a una enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41; agudizada&#44; tratados con ventilaci&#243;n mec&#225;nica invasiva&#46; Los objetivos secundarios fueron identificar los factores pron&#243;sticos de la mortalidad hospitalaria y a los 2 a&#241;os&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes Y M&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se estudi&#243; retrospectivamente a 101 pacientes con sospecha de EPOC tratados en la unidad de cuidados intensivos de un hospital universitario entre julio de 1993 y diciembre de 1998&#46; Se realizaron un an&#225;lisis univariado y otro de regresi&#243;n log&#237;stica de las posibles variables relacionadas con la mortalidad&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">La supervivencia hospitalaria fue del 74&#44;3&#37; y a los 2 a&#241;os del 55&#44;4&#37;&#46; La supervivencia a los 2 a&#241;os fue del 81&#37; para los pacientes dados de alta del hospital&#46; Las variables asociadas con la mortalidad hospitalaria fueron la edad superior a los 65 a&#241;os&#44; el diagn&#243;stico electrocardiogr&#225;-fico de <span class="elsevierStyleItalic">cor pulmonale</span> cr&#243;nico y el desarrollo de un s&#237;ndrome de disfunci&#243;n multiorg&#225;nica&#46; No se identificaron factores predictores de mortalidad a los 2 a&#241;os&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los pacientes con EPOC agudizada que requieren ventilaci&#243;n mec&#225;nica tienen una supervivencia hospitalaria buena y una supervivencia a los 2 a&#241;os acepta-ble&#46; La edad&#44; la presencia de signos electrocardiogr&#225;ficos de <span class="elsevierStyleItalic">cor pulmonale</span> y el desarrollo de s&#237;ndrome de disfunci&#243;n multiorg&#225;nica se asociaron a una mayor mortalidad hospitalaria&#46;</p>"
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Original Articles
In-Hospital and 2-Year Survival of Patients Treated With Mechanical Ventilation for Acute Exacerbation of COPD
J.M. Rauricha,
Corresponding author
jmraurich@hsd.es

Correspondence: Dr. J.M. Raurich. Servicio de Medicina Intensiva. Hospital Universitario Son Dureta. Andrea Doria, 55. 07014 Palma de Majorca. España
, J. Péreza, J. Ibáñeza, S. Roiga, S. Batleb
a Servicio de Medicina Intensiva, Hospital Universitario Son Dureta, Palma de Majorca, Spain
b Servicio de Neumología, Hospital Universitario Son Dureta, Palma de Majorca, Spain
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO analyze in-hospital and 2-year survival of patients who require mechanical ventilation with intubation after acute respiratory failure due to exacerbation of chronic obstructive pulmonary disease &#40;COPD&#41;&#46; The secondary objective was to identify the prognostic factors for in-hospital mortality and mortality at 2 years&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We retrospectively studied 101 patients with suspected COPD admitted to the intensive care unit between July 1993 and December 1998&#46; Variables potentially related to mortality were analyzed with a univariate model and by logistic regression&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">In-hospital survival was 74&#46;3&#37; and 2-year survival was 55&#46;4&#37;&#46; Survival at 2 years was 81&#37; for patients discharged from hospital&#46; The variables associated with in-hospital mortality were age greater than 65 years&#44; electrocardiographic diagnosis of chronic cor pulmonale&#44; and development of multiorgan dysfunction syndrome&#46; No factors predictive of mortality at 2 years were identified&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The in-hospital survival rate for patients with an acute exacerbation of COPD who require mechanical ventilation is good and the 2-year survival rate is acceptable&#46; Age&#44; electrocardiographic signs of cor pulmonale&#44; and development of multiorgan dysfunction syndrome were associated with greater risk of in-hospital mortality&#46;</p>"
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Article information
ISSN: 15792129
Original language: English
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