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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO evaluate various methods for studying the perception of dyspnea in chronic obstructive pulmonary disease &#40;COPD&#41; using a new parameter&#44; the change in Borg scale rating&#44; and others already in use&#58; the linear regression slope and the application of Stevens&#39; law to the response-perception curve-ie change in forced expiratory volume in 1 second &#40;&#916;FEV<span class="elsevierStyleInf">1</span>&#41;-change in dyspnea &#40;Adyspnea&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p class="elsevierStyleSimplePara elsevierViewall">A bronchial challenge test was performed on 70 patients with stable COPD and no contraindications for performing the test &#40;European Respiratory Society criteria&#41;&#44; during which dyspnea was measured &#40;Borg scale&#41; after each nebulization&#46; Perception was analyzed using&#58; <span class="elsevierStyleItalic">a</span>&#41; the linear regression slope of &#916;FEV<span class="elsevierStyleInf">1</span> plotted against &#40;Adyspnea&#41;&#59; <span class="elsevierStyleItalic">b</span>&#41; the exponent n of Stevens&#39; law &#40;&#968;&#61;k&#936;n&#44; in which &#968; is &#916;dyspnea and &#936;is AFEV<span class="elsevierStyleInf">1</span>&#44; with perception being poor when n&#60;1 and good when n&#62;1&#41;&#44; and <span class="elsevierStyleItalic">c</span>&#41; change in Borg&#58; difference between dyspnea when FEV<span class="elsevierStyleInf">1</span> has fallen 20&#37; and dyspnea after saline inhalation&#46; Subjects were classified according to the slope and change in Borg as hypoperceivers&#44; normal perceivers&#44; or hyperperceivers&#46; These 2 methods of classification were compared using the &#954; statistic&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">According to the exponent n&#44; all patients were hypoperceivers &#40;n&#60;1&#41;&#46; According to the slope&#44; there were 33 hypoperceivers&#44; 28 normal perceivers&#44; and 9 hyperperceivers&#46; The change in Borg classified 37 subjects as hypoperceivers&#44; 23 as normal perceivers&#44; and 10 as hyperperceivers&#46; All except 5 subjects were classified in the same way by the slope and the change in Borg &#40;&#954;&#61;0&#46;88&#41;&#46; In most of the 5 cases of discrepancy&#44; the slope classified subjects as better perceivers&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The n exponent is not valid for evaluating the perception of dyspnea induced by a bronchial challenge test in COPD&#46; Change in Borg is at least as useful as the slope for evaluating perception of dyspnea&#46; The percentage of patients with this disease who are hyperperceivers is high&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Valorar varios m&#233;todos para el estudio de la percepci&#243;n de la disnea en la enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41; usando un nuevo par&#225;metro&#44; el cambio en Borg &#40;CB&#41;&#44; y otros ya utilizados&#58; la pendiente de la regresi&#243;n lineal y la aplicaci&#243;n de la ley de Stevens a la curva respuesta-percepci&#243;n -cambios en el volumen espiratorio forzado en el primer segundo &#40;&#916;FEV<span class="elsevierStyleInf">1</span>&#41;-cambio en la disnea &#40;&#916;disnea&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; un test de broncoprovocaci&#243;n a 70 pacientes con EPOC estable&#44; sin contraindi-caciones para dicha prueba &#40;criterios de la European Respiratory Society&#41;&#44; durante el que se midi&#243; la disnea &#40;escala de Borg&#41; despu&#233;s de cada nebulizaci&#243;n&#46; La percepci&#243;n se analiz&#243; mediante&#58; <span class="elsevierStyleItalic">a</span>&#41; la pendiente de la regresi&#243;n lineal entre &#916;FEV<span class="elsevierStyleInf">1</span> y Adisnea&#59; <span class="elsevierStyleItalic">b</span>&#41; el exponente n de la ley de Stevens &#40;&#968; &#61; k&#936;<span class="elsevierStyleSup">n</span>&#44; donde &#968; es &#916;disnea y &#968; es &#916;FEV<span class="elsevierStyleInf">1</span>&#59; cuan-do n &#60; 1&#44; la percepci&#243;n es mala&#44; y cuando n &#62; 1&#44; buena&#41;&#44; y <span class="elsevierStyleItalic">c</span>&#41; el CB&#58; diferencia entre la disnea cuando el FEV<span class="elsevierStyleInf">1</span> ha ca&#237;-do un 20&#37; y la disnea tras inhalaci&#243;n de salino&#46; Se clasific&#243; a los sujetos seg&#250;n la pendiente y el CB en hipoperceptores &#40;HPO&#41;&#44; normoperceptores &#40;NP&#41; e hiperperceptores &#40;HPR&#41;&#46; Se compararon ambas clasificaciones mediante el estad&#237;stico kappa&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Seg&#250;n el exponente n todos los pacientes fueron HPO &#40;n &#60; 1&#41;&#46; Seg&#250;n la pendiente hubo 33 HPO&#44; 28 NP y 9 HPR&#46; El CB clasific&#243; como HPO a 37 sujetos&#44; como NP a 23 y como HPR a 10&#46; La pendiente y el CB clasificaron igual a to-dos&#44; excepto a 5 sujetos &#40;kappa &#61; 0&#44;88&#41;&#46; En la mayor&#237;a de casos discordantes&#44; la pendiente clasific&#243; a los sujetos como mejor perceptores&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">El coeficiente n no es v&#225;lido para estudiar la percepci&#243;n de la disnea inducida mediante test de bronco-provocaci&#243;n en la EPOC&#46; El CB es&#44; al menos&#44; tan &#250;til como la pendiente para estos estudios&#46; La proporci&#243;n de HPO entre los pacientes con dicha enfermedad es elevada&#46;</p>"
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How Can We Assess the Perception of Induced Dyspnea in Chronic Obstructive Pulmonary Disease?
M.E. Martínez Francésa,*, M. Prpiñá Torderaa, A. Belloch Fusterb, E.M. Martínez Moragónc, A. de Diego Damiáaa
a Servicio de Neumología, Hospital Universitario La Fe, Valencia, Spain
b Departamento de Personalidad, Universidad de Valencia, Valencia, Spain
c Servicio de Medicina Interna, Hospital Comarcal de Sagunto, Sagunto, Valencia, Spain
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            0 => "Perception"
            1 => "Dyspnea"
            2 => "Chronic obstructive pulmonary disease"
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            0 => "Percepci&#243;n&#46; Disnea"
            1 => "Enfermedad pulmonar obs-tructiva cr&#243;nica"
            2 => "Prueba de provocaci&#243;n bronquila"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">TO evaluate various methods for studying the perception of dyspnea in chronic obstructive pulmonary disease &#40;COPD&#41; using a new parameter&#44; the change in Borg scale rating&#44; and others already in use&#58; the linear regression slope and the application of Stevens&#39; law to the response-perception curve-ie change in forced expiratory volume in 1 second &#40;&#916;FEV<span class="elsevierStyleInf">1</span>&#41;-change in dyspnea &#40;Adyspnea&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p class="elsevierStyleSimplePara elsevierViewall">A bronchial challenge test was performed on 70 patients with stable COPD and no contraindications for performing the test &#40;European Respiratory Society criteria&#41;&#44; during which dyspnea was measured &#40;Borg scale&#41; after each nebulization&#46; Perception was analyzed using&#58; <span class="elsevierStyleItalic">a</span>&#41; the linear regression slope of &#916;FEV<span class="elsevierStyleInf">1</span> plotted against &#40;Adyspnea&#41;&#59; <span class="elsevierStyleItalic">b</span>&#41; the exponent n of Stevens&#39; law &#40;&#968;&#61;k&#936;n&#44; in which &#968; is &#916;dyspnea and &#936;is AFEV<span class="elsevierStyleInf">1</span>&#44; with perception being poor when n&#60;1 and good when n&#62;1&#41;&#44; and <span class="elsevierStyleItalic">c</span>&#41; change in Borg&#58; difference between dyspnea when FEV<span class="elsevierStyleInf">1</span> has fallen 20&#37; and dyspnea after saline inhalation&#46; Subjects were classified according to the slope and change in Borg as hypoperceivers&#44; normal perceivers&#44; or hyperperceivers&#46; These 2 methods of classification were compared using the &#954; statistic&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">According to the exponent n&#44; all patients were hypoperceivers &#40;n&#60;1&#41;&#46; According to the slope&#44; there were 33 hypoperceivers&#44; 28 normal perceivers&#44; and 9 hyperperceivers&#46; The change in Borg classified 37 subjects as hypoperceivers&#44; 23 as normal perceivers&#44; and 10 as hyperperceivers&#46; All except 5 subjects were classified in the same way by the slope and the change in Borg &#40;&#954;&#61;0&#46;88&#41;&#46; In most of the 5 cases of discrepancy&#44; the slope classified subjects as better perceivers&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The n exponent is not valid for evaluating the perception of dyspnea induced by a bronchial challenge test in COPD&#46; Change in Borg is at least as useful as the slope for evaluating perception of dyspnea&#46; The percentage of patients with this disease who are hyperperceivers is high&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Valorar varios m&#233;todos para el estudio de la percepci&#243;n de la disnea en la enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41; usando un nuevo par&#225;metro&#44; el cambio en Borg &#40;CB&#41;&#44; y otros ya utilizados&#58; la pendiente de la regresi&#243;n lineal y la aplicaci&#243;n de la ley de Stevens a la curva respuesta-percepci&#243;n -cambios en el volumen espiratorio forzado en el primer segundo &#40;&#916;FEV<span class="elsevierStyleInf">1</span>&#41;-cambio en la disnea &#40;&#916;disnea&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; un test de broncoprovocaci&#243;n a 70 pacientes con EPOC estable&#44; sin contraindi-caciones para dicha prueba &#40;criterios de la European Respiratory Society&#41;&#44; durante el que se midi&#243; la disnea &#40;escala de Borg&#41; despu&#233;s de cada nebulizaci&#243;n&#46; La percepci&#243;n se analiz&#243; mediante&#58; <span class="elsevierStyleItalic">a</span>&#41; la pendiente de la regresi&#243;n lineal entre &#916;FEV<span class="elsevierStyleInf">1</span> y Adisnea&#59; <span class="elsevierStyleItalic">b</span>&#41; el exponente n de la ley de Stevens &#40;&#968; &#61; k&#936;<span class="elsevierStyleSup">n</span>&#44; donde &#968; es &#916;disnea y &#968; es &#916;FEV<span class="elsevierStyleInf">1</span>&#59; cuan-do n &#60; 1&#44; la percepci&#243;n es mala&#44; y cuando n &#62; 1&#44; buena&#41;&#44; y <span class="elsevierStyleItalic">c</span>&#41; el CB&#58; diferencia entre la disnea cuando el FEV<span class="elsevierStyleInf">1</span> ha ca&#237;-do un 20&#37; y la disnea tras inhalaci&#243;n de salino&#46; Se clasific&#243; a los sujetos seg&#250;n la pendiente y el CB en hipoperceptores &#40;HPO&#41;&#44; normoperceptores &#40;NP&#41; e hiperperceptores &#40;HPR&#41;&#46; Se compararon ambas clasificaciones mediante el estad&#237;stico kappa&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Seg&#250;n el exponente n todos los pacientes fueron HPO &#40;n &#60; 1&#41;&#46; Seg&#250;n la pendiente hubo 33 HPO&#44; 28 NP y 9 HPR&#46; El CB clasific&#243; como HPO a 37 sujetos&#44; como NP a 23 y como HPR a 10&#46; La pendiente y el CB clasificaron igual a to-dos&#44; excepto a 5 sujetos &#40;kappa &#61; 0&#44;88&#41;&#46; En la mayor&#237;a de casos discordantes&#44; la pendiente clasific&#243; a los sujetos como mejor perceptores&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">El coeficiente n no es v&#225;lido para estudiar la percepci&#243;n de la disnea inducida mediante test de bronco-provocaci&#243;n en la EPOC&#46; El CB es&#44; al menos&#44; tan &#250;til como la pendiente para estos estudios&#46; La proporci&#243;n de HPO entre los pacientes con dicha enfermedad es elevada&#46;</p>"
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