Hipertension arterial pulmonar por sindrome crest
Pulmonary arterial hypertension by crest's syndrome
* Médico Adjunto al Servicio de Neumología. (I.N.S.). Instituto Nacional de Silicosis. Hospital General de Asturias. Oviedo
** Jefe Clínico Servido de Neumología (I.N.S.). Instituto Nacional de Silicosis. Hospital General de Asturias. Oviedo
*** Jeté del Servicio de Anatomía Patoiógéca (H.G.A.) Instituto Nacional de Silicosis. Hospital General de Asturias. Oviedo
**** Jefe del Servicio de Neumología (I.N.S.). Instituto Nacional de Silicosis. Hospital General de Asturias. Oviedo
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"apellidos" => "Carretero Sastre" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "A." "apellidos" => "Ribas Barceló" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "J.A." "apellidos" => "Mosquera Pestaña" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">****</span>" "identificador" => "aff0020" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Médico Adjunto al Servicio de Neumología. (I.N.S.). Instituto Nacional de Silicosis. Hospital General de Asturias. Oviedo" "etiqueta" => "*" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Jefe Clínico Servido de Neumología (I.N.S.). Instituto Nacional de Silicosis. Hospital General de Asturias. Oviedo" "etiqueta" => "**" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Jeté del Servicio de Anatomía Patoiógéca (H.G.A.) Instituto Nacional de Silicosis. Hospital General de Asturias. Oviedo" "etiqueta" => "***" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Jefe del Servicio de Neumología (I.N.S.). Instituto Nacional de Silicosis. Hospital General de Asturias. Oviedo" "etiqueta" => "****" "identificador" => "aff0020" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Pulmonary arterial hypertension by crest's syndrome" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1978-01-04" "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se presenta 1 paciente de 52 años con disnea progresiva de 4 años deevolución, clínica recidivante de fallo cardiaco derecho, telangiectasias, esclerodactilica y Raynaud bilateral.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Sus volúmenes pulmonares, resis tencias al flujo, compliance stática y DLCO eran normales.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Electrocardiograma y Vectocardiograma mostraba hipertrofia de ventrículo derecho. El cateterismo derecho e izquierdo mostró hipertensión pulmonar severa con presión en cuña normal y sin patología del corazón izquierdo. La angiografía pulmonar descartó tromboembolismo de grandes troncos arteriales.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La biopsia pulmonar abierta mostró moderada fibrosis intesticial y, sobre todo, acentuadas lesiones en la íntima de las arterias de mediano y pequeño calibre.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">El diagnóstico etiopatogénico de la hipertensión pulmonar es difícil y exige medidas diagnósticas agresivas para separar las distintas entidades que lo producen y especialmente tromboembolismo pulmonar de pequeños vasos.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Calcinosis, Raynaud, esclerodactilia, afectación de esófago y telangiectasias (síndrome de CREST o CRST), son formas menores de esclerosis sisténtica y se han considerado de pronostico benigno.</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Este paciente, junto a otros 13 descritos en la literatura son portadores de una hipertensión pulmonar por lesión vascular, poniendo en tela de juicio la benignidad del proceso.</p></span>" ] "en" => array:2 [ "titulo" => "Summary" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">The authors present the case of a 52-year-old patient with progressive dyspnea with a 4 year evolution, dinical relapse of right cardiac failure, telangiectasia, sclerodactylia and bilateral Raynaud.</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">His pulmonary volumes, resistance to flow, static compliance and DLCO were normal.</p><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">The electrocardiogram and vectora rdiogram showed hypertrophy of the right ventride. Right and left catheterism showed severe pulmonary hypertension with pressure in normal wedge and without pathology of the left heart. Pulmonary angiography discarted thrombo-embolism of large arterial trunks.</p><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Open pulmonary biopsy showed moderated interstitial fibrosis and, above all, acentuated lesions in the intima of the arteries of medium and small caliber.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "titulo" => "Editorial Pulmonary veno-occlusive disease" ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Brit. Med. J." 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 3 | 3 | 6 |
| 2024 October | 68 | 29 | 97 |
| 2024 September | 83 | 15 | 98 |
| 2024 August | 96 | 44 | 140 |
| 2024 July | 74 | 31 | 105 |
| 2024 June | 89 | 33 | 122 |
| 2024 May | 101 | 41 | 142 |
| 2024 April | 71 | 24 | 95 |
| 2024 March | 68 | 35 | 103 |
| 2024 February | 60 | 48 | 108 |
| 2024 January | 0 | 4 | 4 |
| 2023 December | 0 | 2 | 2 |
| 2023 November | 0 | 3 | 3 |
| 2023 October | 0 | 4 | 4 |
| 2023 September | 0 | 2 | 2 |
| 2023 August | 0 | 3 | 3 |
| 2023 July | 0 | 13 | 13 |
| 2023 June | 0 | 2 | 2 |
| 2023 March | 22 | 3 | 25 |
| 2023 February | 51 | 24 | 75 |
| 2023 January | 50 | 26 | 76 |
| 2022 December | 75 | 27 | 102 |
| 2022 November | 93 | 22 | 115 |
| 2022 October | 71 | 44 | 115 |
| 2022 September | 98 | 16 | 114 |
| 2022 August | 88 | 53 | 141 |
| 2022 July | 64 | 44 | 108 |
| 2022 June | 86 | 35 | 121 |
| 2022 May | 99 | 35 | 134 |
| 2022 April | 93 | 38 | 131 |
| 2022 March | 76 | 42 | 118 |
| 2022 February | 73 | 31 | 104 |
| 2022 January | 88 | 33 | 121 |
| 2021 December | 52 | 41 | 93 |
| 2021 November | 45 | 50 | 95 |
| 2021 October | 32 | 45 | 77 |
| 2021 September | 35 | 35 | 70 |
| 2021 August | 36 | 28 | 64 |
| 2021 July | 21 | 44 | 65 |
| 2021 June | 23 | 39 | 62 |
| 2021 May | 25 | 23 | 48 |
| 2021 April | 45 | 25 | 70 |
| 2021 March | 46 | 18 | 64 |
| 2021 February | 46 | 10 | 56 |
| 2021 January | 41 | 28 | 69 |
| 2020 December | 33 | 14 | 47 |
| 2020 November | 38 | 21 | 59 |
| 2020 October | 37 | 18 | 55 |
| 2020 September | 27 | 11 | 38 |
| 2020 August | 30 | 12 | 42 |
| 2020 July | 35 | 16 | 51 |
| 2020 June | 34 | 9 | 43 |
| 2020 May | 35 | 11 | 46 |
| 2020 April | 31 | 15 | 46 |
| 2020 March | 20 | 17 | 37 |
| 2020 February | 25 | 29 | 54 |
| 2020 January | 26 | 29 | 55 |
| 2019 December | 46 | 31 | 77 |
| 2019 November | 25 | 5 | 30 |
| 2019 October | 44 | 23 | 67 |
| 2019 September | 53 | 28 | 81 |
| 2019 August | 23 | 22 | 45 |
| 2019 July | 39 | 24 | 63 |
| 2019 June | 50 | 27 | 77 |
| 2019 May | 51 | 24 | 75 |
| 2019 April | 50 | 29 | 79 |
| 2019 March | 16 | 24 | 40 |
| 2019 February | 4 | 15 | 19 |
| 2019 January | 5 | 7 | 12 |
| 2018 December | 5 | 14 | 19 |
| 2018 November | 25 | 14 | 39 |
| 2018 October | 28 | 21 | 49 |
| 2018 September | 14 | 8 | 22 |
| 2018 May | 9 | 0 | 9 |
| 2018 April | 8 | 8 | 16 |
| 2018 March | 4 | 6 | 10 |
| 2018 February | 9 | 12 | 21 |
| 2018 January | 5 | 4 | 9 |
| 2017 December | 11 | 9 | 20 |
| 2017 November | 10 | 9 | 19 |
| 2017 October | 7 | 8 | 15 |
| 2017 September | 11 | 2 | 13 |
| 2017 August | 12 | 11 | 23 |
| 2017 July | 5 | 4 | 9 |
| 2017 June | 10 | 26 | 36 |
| 2017 May | 15 | 11 | 26 |
| 2017 April | 4 | 4 | 8 |
| 2017 March | 7 | 6 | 13 |
| 2017 February | 6 | 7 | 13 |
| 2017 January | 5 | 8 | 13 |
| 2016 December | 11 | 9 | 20 |
| 2016 November | 12 | 10 | 22 |
| 2016 October | 11 | 11 | 22 |
| 2016 September | 11 | 11 | 22 |
| 2016 August | 11 | 6 | 17 |
| 2016 July | 24 | 6 | 30 |
| 2016 June | 24 | 13 | 37 |
| 2016 May | 13 | 7 | 20 |
| 2016 April | 19 | 0 | 19 |
| 2016 March | 11 | 1 | 12 |
| 2016 February | 14 | 0 | 14 |
| 2016 January | 22 | 17 | 39 |
| 2015 December | 25 | 15 | 40 |
| 2015 November | 22 | 6 | 28 |
| 2015 October | 5 | 1 | 6 |
| 2015 September | 2 | 0 | 2 |
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