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array:22 [ "pii" => "S0300289615325217" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)32521-7" "estado" => "S300" "fechaPublicacion" => "1980-01-01" "aid" => "72590" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "1980" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "abs" "cita" => "Arch Bronconeumol. 1980;16:37-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1026 "formatos" => array:3 [ "EPUB" => 57 "HTML" => 556 "PDF" => 413 ] ] "itemAnterior" => array:18 [ "pii" => "S0300289615325205" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)32520-5" "estado" => "S300" "fechaPublicacion" => "1980-01-01" "aid" => "72589" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "abs" "cita" => "Arch Bronconeumol. 1980;16:37" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 872 "formatos" => array:3 [ "EPUB" => 43 "HTML" => 443 "PDF" => 386 ] ] "es" => array:8 [ "idiomaDefecto" => true "titulo" => "Small Cell Lung Cancer. Complete Remission and Improved Survival" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "37" ] ] "contieneResumen" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615325205?idApp=UINPBA00003Z" "url" => "/03002896/0000001600000001/v1_201509151242/S0300289615325205/v1_201509151242/es/main.assets" ] "es" => array:8 [ "idiomaDefecto" => true "titulo" => "Cystic Fibrosis in adults. 75 cases and a review of 232 cases in the literature" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "37" "paginaFinal" => "38" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "tieneResumen" => true "resumen" => array:1 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La fibrosis quística es la causa más frecuente de enfermedad broncopulmonar inespecífica crónica y de insuficiencia pancreática en las tres primeras décadas de la vida en EE.UU.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se describen 75 enfermos de 18 a 47 años y se analizan 232 revisados. Los 307 pacientes tenían el Cl y Na del sudor elevados, que constituye un excelente método discriminativo aún en pacientes de mayor edad para la fibrosis quístiea (FQ).</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">97% tenían bronconeumopatía crónica y ésta constituía la causa más importante de mortalidad y morbilidad y era diferente de las bronconeumopatías crónicas de otras etiologías.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">El descenso progresivo del estado clínico de los enfermos se marcaba por exacerbaciones sintomáticas recurrentes de la broncopatía bacteriana crónica causada por Pseudomona aeruginosa y Staphtiococcus aureus y finaliza en insuficiencia respiratoria, cor pulmonale y exitus.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La bronconeumopatía se complica en un 60% de los casos de hemoptisis que en un 7% de ellas es masiva y en 16% de neumotorax, problemas raros per se en los niños. Todos los sujetos examinados radiológicamente presentaron sinusitis y 48% tenían poliposis nasal. Un 95% de los estudiados tenían insuficiencia pancreática, pero raramente sintomática aunque persisten la esteatorrea y azatorrea masivas. El equivalente al íleo meconial (acumulo fecal) e invaginación intestinal son frecuentes en el adulto (21%) y raro en los niños, y requiere diagnóstico inmediato y terapéutica con enemas de diatrizato sódico. Otras complicaciones constituyen: glucosuria, cirrosis biliar, colestasis, aspermia.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">El peso y la altura se encuentran en el límite inferior de la normalidad, pero el 16% de los hombres estudiados medían 180 cm. y un 7% pesaban demasiado. Por lo tanto hay que tener un alto grado de sospecha clínica para el diagnóstico, pues frecuentemente pacientes con FQ aparentan buena salud.</p></span>" ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000001600000001/v1_201509151242/S0300289615325217/v1_201509151242/es/main.assets" "Apartado" => array:4 [ "identificador" => "43822" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Referatas" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000001600000001/v1_201509151242/S0300289615325217/v1_201509151242/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615325217?idApp=UINPBA00003Z" ]
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