Statistics

 array:22 [
  "pii" => "S0300289615325059"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)32505-9"
  "estado" => "S300"
  "fechaPublicacion" => "1980-01-01"
  "aid" => "72574"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
  "copyrightAnyo" => "1980"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 1980;16:1-3"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1099
    "formatos" => array:3 [
      "EPUB" => 54
      "HTML" => 600
      "PDF" => 445
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615325060"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32506-0"
    "estado" => "S300"
    "fechaPublicacion" => "1980-01-01"
    "aid" => "72575"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1980;16:4-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1132
      "formatos" => array:3 [
        "EPUB" => 53
        "HTML" => 600
        "PDF" => 479
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Estenosis traqueales yatrogenicas"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "4"
          "paginaFinal" => "6"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Iatrogenic tracheal stenosis"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "A. Clariana Pal, J.P. Díaz Jiménez, R. Coll Artés, L. Muñoz Díaz"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "A."
              "apellidos" => "Clariana Pal"
            ]
            1 => array:2 [
              "nombre" => "J.P."
              "apellidos" => "Díaz Jiménez"
            ]
            2 => array:2 [
              "nombre" => "R."
              "apellidos" => "Coll Artés"
            ]
            3 => array:2 [
              "nombre" => "L."
              "apellidos" => "Muñoz Díaz"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615325060?idApp=UINPBA00003Z"
    "url" => "/03002896/0000001600000001/v1_201509151242/S0300289615325060/v1_201509151242/es/main.assets"
  ]
  "es" => array:12 [
    "idiomaDefecto" => true
    "titulo" => "Avances en el tratamiento del carcinoma broncopulmonar inoperable: estudio comparativo entre radioterapia aislada tipo split-course y una asociacion radio-quimio-inmunoterapica"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "1"
        "paginaFinal" => "3"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "H. Pourquier, J.B. Dubois, A. Valls-Fontanals, B. Serrou, F.B. Michel"
        "autores" => array:5 [
          0 => array:3 [
            "nombre" => "H."
            "apellidos" => "Pourquier"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "J&#46;B&#46;"
            "apellidos" => "Dubois"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "Valls-Fontanals"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "B&#46;"
            "apellidos" => "Serrou"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;&#42;</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "F&#46;B&#46;"
            "apellidos" => "Michel"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;&#42;&#42;</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Servicio de Radioterapia&#46; Centro Paul Lamarque&#46; Clinique St&#46; Eloi&#46; Montpellier 34059&#46; Montpellier"
            "etiqueta" => "&#42;"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Quimio-inmunoterapia&#46; Centro Paul Lmarque&#46; Clinique St&#46; Eloi&#46; Montpellier 34059&#46; Montpellier"
            "etiqueta" => "&#42;&#42;"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Servicio de Neumonolog&#237;a&#46; Clinique Aiguelongue 34000&#46; Montpellier"
            "etiqueta" => "&#42;&#42;&#42;"
            "identificador" => "aff0015"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Advances in the treatment of inoperable bronchopulmonary carcinoma&#58; comparative study between isolated split-course type radiotherapy and a radio-chemo-immunotherapeutic association"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1979-02-13"
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span id="absec0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Los autores demuestran en un estudio comparativo con distribuci&#243;n al azar&#44; sobre 64 pacientes afectos de carcinoma broncopulmonar inoperable&#44; la superioridad&#44; en cuanto a supervivencia&#44; de una asociaci&#243;n radio quimio inmunoterapia sobre la radioterapia aislada&#46;</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">Los tratamientos empleados consisten en una radioterapia tipo <span class="elsevierStyleItalic">splitcourse</span> &#40;dos tandas de 2&#46;000 rads en cinco sesiones&#44; separadas por tres semanas de reposo&#41; com&#250;n a los dos grupos&#44; y una quimio-inmunoterapia a base de Adriamicina &#40;50 mg&#47;m<span class="elsevierStyleSup">2</span>&#41;&#44; Vincristina &#40;1 mg&#47;m<span class="elsevierStyleSup">2</span>&#41;&#44; CCNNU &#40;50 mg&#47;m<span class="elsevierStyleSup">2</span>&#41; y 5-FU &#40;500 mg&#47;m<span class="elsevierStyleSup">2</span>&#41;&#44; seguida de la administraci&#243;n por escarificaci&#243;n&#44; de 150 mg&#46; de BCG fresca&#44; los d&#237;as 14&#44; 21&#44; 28 y 35&#46;</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">La supervivencia a un a&#241;o es de 49&#44;3 &#37;&#44; mientras que para el grupo control&#44; s&#243;lo tratado con radioterapia&#44; &#233;sta es de 29&#46;1 &#37;&#46;</p></span>"
      ]
      "en" => array:2 [
        "titulo" => "Summary"
        "resumen" => "<span id="absec0010" class="elsevierStyleSection elsevierViewall"><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">In a comparative study with random distribution of 64 patients suffering from inoperable bronchopulmonary carcinoma the authors demonstrate the superiority of a radio-chemo-immunotherapeutic association over isolated radiotherapy insofar as survival is concerned&#46;</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">The treatments used consisted of split-course type radiotherapy &#40;two series of 2000 rads in five sessions&#44; separated by three weeks of rest&#41; common to both groups&#44; and chemo-immuno-therapy based on Adriamycin &#40;50 mg&#47;m<span class="elsevierStyleSup">2</span>&#41;&#44; Vincristine &#40;1 mg&#47;m<span class="elsevierStyleSup">2</span>&#41;&#44; CCNU &#40;50 mg&#47;m<span class="elsevierStyleSup">2</span>&#41; and 5-FU &#40;500 mg&#47;m<span class="elsevierStyleSup">2</span>&#41;&#44; followed by the administration by scarification of 150 mg of fresh BCG on the 14th&#44; 21 st&#46; 28th and 35th days&#46;</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall">The survival rate at one year was of 49&#46;3 &#37; whereas that for the control group&#44; treated only with radiotherapy&#44; was of 29&#46;1 &#37;&#46;</p></span>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:34 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Indications for and results of irradiation of carcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "W&#46;L&#46; Caldwell"
                            1 => "M&#46;A&#46; Bagshaw"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1968"
                        "volumen" => "22"
                        "paginaInicial" => "999"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4176760"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparison of split-course radiation therapy for unresectable bronchogenic carcinoma&#58; 5 years results"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;E&#46; Lee"
                            1 => "D&#46;T&#46; Carr"
                            2 => "D&#46;S&#46; Childs"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Amer&#46; J&#46; Roentgenol"
                        "fecha" => "1976"
                        "volumen" => "126"
                        "paginaInicial" => "116"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiation therapy in the management of carcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "C&#46;A&#46; Perez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1977"
                        "volumen" => "39"
                        "paginaInicial" => "901"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/189898"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "La radioth&#233;rapie dans le traitement des &#233;pith&#233;liomas bronchiques"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "H&#46; Porquier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Poumon et coeur"
                        "fecha" => "1973"
                        "volumen" => "29"
                        "paginaInicial" => "737"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The results of split-course radiation therapy in cancer of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "H&#46; Scruggs"
                            1 => "E&#46;L&#46; Mahdi a"
                            2 => "R&#46;D&#46; Marks"
                            3 => "W&#46;C&#46; Constable"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Amer&#46; J&#46; Roentgenol"
                        "fecha" => "1974"
                        "volumen" => "121"
                        "paginaInicial" => "754"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4139900"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cancer of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "H&#46;G&#46; Seydel"
                            1 => "A&#46; Chait"
                            2 => "J&#46;T&#46; Gmelich"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1975"
                        "editorial" => "J&#46; Wiley and Sons"
                        "editorialLocalizacion" => "New York"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Supervoltage roetgen therapy in cancer of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "T&#46;A&#46; Watson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Amer&#46; J&#46; Roentgenol"
                        "fecha" => "1956"
                        "volumen" => "75"
                        "paginaInicial" => "525"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13292602"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Short-course radiation therapy in carcinoma of lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "N&#46; Abramson"
                            1 => "P&#46;J&#46; Cavanaugh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1148/96.3.627"
                      "Revista" => array:5 [
                        "tituloSerie" => "Radiology"
                        "fecha" => "1970"
                        "volumen" => "96"
                        "paginaInicial" => "627"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5456318"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Short-course radiation therapy in carcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "N&#46; Abramson"
                            1 => "P&#46;J&#46; Cavanaugh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1148/108.3.685"
                      "Revista" => array:5 [
                        "tituloSerie" => "Radiology"
                        "fecha" => "1973"
                        "volumen" => "108"
                        "paginaInicial" => "685"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4723669"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radical irradiation with the split-course technique in carcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46;A&#46; Aristizabal"
                            1 => "W&#46;L&#46; Caldwell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1976"
                        "volumen" => "37"
                        "paginaInicial" => "2630"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/949682"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparative analysis of two regimens of split-course radiation in carcinoma of lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46;T&#46; Guthrie"
                            1 => "J&#46;J&#46; Ptacek"
                            2 => "A&#46;C&#46; Hass"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Amer&#46; J&#46; Roentgenol&#46;"
                        "fecha" => "1973"
                        "volumen" => "117"
                        "paginaInicial" => "605"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4693020"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survival in carcinoma of the lung after a split-course of radiotherapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "T&#46;A&#46; Hazra"
                            1 => "M&#46;S&#46; Chandra Sekaran"
                            2 => "M&#46; Colman"
                            3 => "T&#46;H&#46; Prempree"
                            4 => "A&#46; Inalsingh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1259/0007-1285-47-560-464"
                      "Revista" => array:5 [
                        "tituloSerie" => "Brit&#46; J&#46; Radiol"
                        "fecha" => "1976"
                        "volumen" => "47"
                        "paginaInicial" => "464"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4421602"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiation reaction in the lung after continous and splitcourse megavoltage radiotherapy of bronchial carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "L&#46;R&#46; Holsti"
                            1 => "P&#46; Vuorinen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1259/0007-1285-40-472-280"
                      "Revista" => array:5 [
                        "tituloSerie" => "Brit&#46; J&#46; Radiol"
                        "fecha" => "1967"
                        "volumen" => "40"
                        "paginaInicial" => "280"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4960400"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Radiotherapy of bronchogenic carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46;E&#46; Lee"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Seminars in Oncology"
                        "fecha" => "1974"
                        "volumen" => "1"
                        "paginaInicial" => "245"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4143487"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Split dose intensive radiation therapy of advances lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;H&#46; Levitt"
                            1 => "C&#46;P&#46; Bogardus"
                            2 => "G&#46; Ladd"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1148/88.6.1159"
                      "Revista" => array:5 [
                        "tituloSerie" => "Radiology"
                        "fecha" => "1966"
                        "volumen" => "88"
                        "paginaInicial" => "1159"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4960785"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Initial experience with split-dose periodic radiation therapy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46;W&#46; Scanlon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Amer&#46; J&#46; Roentgenol"
                        "fecha" => "1960"
                        "volumen" => "84"
                        "paginaInicial" => "632"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13747046"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Split-dose radiotherapy Prog&#46; Clin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46;W&#46; Scanlon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/nrc723"
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1966"
                        "volumen" => "2"
                        "paginaInicial" => "143"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12635177"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tratamiento del c&#225;ncer de pulm&#243;n inoperable mediante radioterapia concentrada"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Valls Fontanals"
                            1 => "H&#46; Pour-Quier"
                            2 => "F&#46;B&#46; Michel"
                            3 => "J&#46;B&#46; Dubois"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Med&#46; Clin&#46;"
                        "fecha" => "1979"
                        "volumen" => "72"
                        "paginaInicial" => "185"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "La radioterapia concentrada tipo split-course en el tratamiento del c&#225;ncer de pulm&#243;n inoperable"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46; Valls Fontanals"
                            1 => "J&#46;B&#46; Dubois"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Radiolog&#237;a"
                        "fecha" => "1978"
                        "volumen" => "20"
                        "paginaInicial" => "341"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Advantages and disadvantages of intensive split-dose radiation therapy&#46;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46;H&#46; Levitt"
                            1 => "G&#46;R&#46; Bogardus Jr&#46;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "In&#58; Frontiers of radiation therapy and Oncology"
                        "fecha" => "1968"
                        "paginaInicial" => "163"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0105"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical experience with split-course radiotherapy&#46; A randomized clinical trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "L&#46;R&#46; Holsti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1148/92.3.591"
                      "Revista" => array:5 [
                        "tituloSerie" => "Radiology"
                        "fecha" => "1968"
                        "volumen" => "92"
                        "paginaInicial" => "591"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5779694"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0110"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Theoretical aspects of dose-time factors in radioterapy techn&#237;que"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46;K&#46; Sambrook"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Clin&#44; radiology"
                        "fecha" => "1963"
                        "volumen" => "14"
                        "paginaInicial" => "290"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0115"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Split-course radiation therapy in malignant tumors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46;K&#46; Sambrook"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Amer&#46; J&#46; Roentgenol&#46;"
                        "fecha" => "1964"
                        "volumen" => "91"
                        "paginaInicial" => "37"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14117651"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0120"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of bronchogenic carcinoma with simultaneous or sequential combination chemotherapy&#44; including Methotrexate Cyclophosphamide&#44; Procarbazine and Vincristine"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46; Alberto"
                            1 => "K&#46;W&#46; Brunner"
                            2 => "G&#46; Martz"
                            3 => "J&#46;P&#46; Obrecht"
                            4 => "R&#46;W&#46; Sonntag"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1976"
                        "volumen" => "38"
                        "paginaInicial" => "2208"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/187313"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0125"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adjuvant chemotherapy in lung cancer&#46; Review and Prospects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;S&#46; Legha"
                            1 => "F&#46;M&#46; Muggia"
                            2 => "S&#46;K&#46; Carter"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1977"
                        "volumen" => "39"
                        "paginaInicial" => "1415"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/192430"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0130"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "La chimioth&#233;rapie des cancers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "G&#46; Mathe"
                            1 => "Y&#46; Keinis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "Expansion scientifique"
                        "fecha" => "1975"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0135"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical report on the treatment of locally advanced lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "Z&#46; Petrovich"
                            1 => "W&#46; Mietlowski"
                            2 => "M&#46; Ohanian"
                            3 => "J&#46; Cox"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1977"
                        "volumen" => "40"
                        "paginaInicial" => "72"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/195709"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0140"
              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Inmunological overshoot phenomenon following cancer chemotherapy&#58; significance in prognosis evaluation of solid tumors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "B&#46; Serrou"
                            1 => "J&#46;B&#46; Dubois"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Biomedicine"
                        "fecha" => "1975"
                        "volumen" => "23"
                        "paginaInicial" => "41"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/809069"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0145"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Combination chemotherapy in advanced lung cancer with increased survival"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;J&#46; Straus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1976"
                        "volumen" => "38"
                        "paginaInicial" => "2232"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/187314"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Therapy of avanced squamous carcinoma of the lung Cyclophosphamide versus COMB"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "G&#46;P&#46; Bodey"
                            1 => "S&#46;W&#46; Lagakos"
                            2 => "A&#46;C&#46; Gutierrez"
                            3 => "H&#46;E&#46; Wilson"
                            4 => "O&#46;S&#46; Selawry"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1977"
                        "volumen" => "39"
                        "paginaInicial" => "1026"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/71943"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            30 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "31&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Combination chemotherapy of advanced lung cancer&#46; A randomized trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:7 [
                            0 => "H&#46;H&#46; Hansen"
                            1 => "O&#46;S&#46; Selawry"
                            2 => "R&#46; Simon"
                            3 => "D&#46;T&#46; Carr"
                            4 => "C&#46;E&#46; Van Wyck"
                            5 => "R&#46;D&#46; Tucker"
                            6 => "R&#46; Sealy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1976"
                        "volumen" => "38"
                        "paginaInicial" => "2201"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/187312"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            31 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "32&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A 5-year contolled study of BCG and Radiotherapy for inoperable lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46; Pines"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1976"
                        "volumen" => "1"
                        "paginaInicial" => "380"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2563527"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            32 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "33&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Inmunochemotherapy with Corynebacterium Parvum in disseminated cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "L&#46; Israel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Ann&#46; N&#46;Y&#46; Acand&#46; Sci&#46;"
                        "fecha" => "1976"
                        "volumen" => "277"
                        "paginaInicial" => "241"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            33 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "34&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Inmunotherapy of human solid tumors with Bacillus Calmette-Guerin&#58; prolongation of disease-free interval and survival in malignant melanoma&#44; breast and colo-rectal cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;V&#46; Gutterman"
                            1 => "G&#46;M&#46; Mavligit"
                            2 => "G&#46; Blumenshein"
                            3 => "M&#46;A&#46; Borgess"
                            4 => "C&#46;M&#46; Mcbride"
                            5 => "E&#46;M&#46; Hersh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "N&#46;Y&#46; Acad&#46; Sci"
                        "fecha" => "1976"
                        "volumen" => "277"
                        "paginaInicial" => "135"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000001600000001/v1_201509151242/S0300289615325059/v1_201509151242/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9277"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000001600000001/v1_201509151242/S0300289615325059/v1_201509151242/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615325059?idApp=UINPBA00003Z"
]