array:23 [
  "pii" => "S0300289615324832"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)32483-2"
  "estado" => "S300"
  "fechaPublicacion" => "1980-07-01"
  "aid" => "72552"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
  "copyrightAnyo" => "1980"
  "documento" => "simple-article"
  "crossmark" => 0
  "subdocumento" => "abs"
  "cita" => "Arch Bronconeumol. 1980;16:135"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 913
    "formatos" => array:3 [
      "EPUB" => 44
      "HTML" => 487
      "PDF" => 382
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615324844"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32484-4"
    "estado" => "S300"
    "fechaPublicacion" => "1980-07-01"
    "aid" => "72553"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "abs"
    "cita" => "Arch Bronconeumol. 1980;16:135"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 910
      "formatos" => array:3 [
        "EPUB" => 43
        "HTML" => 452
        "PDF" => 415
      ]
    ]
    "es" => array:8 [
      "idiomaDefecto" => true
      "titulo" => "Small Cel Carcinoma of the Lung. Experience with a six-drug Regimen"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => "es"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "135"
        ]
      ]
      "contieneResumen" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615324844?idApp=UINPBA00003Z"
    "url" => "/03002896/0000001600000003/v1_201509151256/S0300289615324844/v1_201509151256/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0300289615324820"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32482-0"
    "estado" => "S300"
    "fechaPublicacion" => "1980-07-01"
    "aid" => "72551"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "abs"
    "cita" => "Arch Bronconeumol. 1980;16:135"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1052
      "formatos" => array:3 [
        "EPUB" => 45
        "HTML" => 579
        "PDF" => 428
      ]
    ]
    "es" => array:8 [
      "idiomaDefecto" => true
      "titulo" => "Anaerobic pleural and pulmonary infections"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => "es"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "135"
        ]
      ]
      "contieneResumen" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615324820?idApp=UINPBA00003Z"
    "url" => "/03002896/0000001600000003/v1_201509151256/S0300289615324820/v1_201509151256/es/main.assets"
  ]
  "es" => array:8 [
    "idiomaDefecto" => true
    "titulo" => "Cytotoxic drug-induced pulmonary disease: Update 1980"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "135"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "tieneResumen" => true
    "resumen" => array:1 [
      "es" => array:1 [
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La administraci&#243;n de algunos citost&#225;ticos se asocia a neumon&#237;a intersticial&#44; alveolitis y fibrosis pulmonar&#46; Algunos de ellos&#58; bleomicina&#44; busulf&#225;n&#44; metothrexate&#44; ya son conocidos como causantes de tales problemas y otros como el clorambucil&#44; la mitomicina y las mostazas nitrogenadas s&#243;lo se han reconocido recientemente&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La interacci&#243;n entre estas drogas y la radiaci&#243;n tor&#225;cica o la administraci&#243;n de ox&#237;geno a altas concentraciones ha producido neumonitis a dosis menores que cuando la droga se administra aisladamente&#46; El sinergismo entre diferentes drogas produce igualmente toxicidad pulmonar a dosis menores&#46; Con algunas drogas y en algunos pacientes&#44; los esteroides disminuyen las anomal&#237;as pulmonares&#44; pero la muerte por hipoxia sigue siendo frecuente&#46; El mejor tratamiento consiste en reconocer el problema y eliminar la droga&#44; por lo que es necesario que el m&#233;dico conozca los efectos de estos medicamentos&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Una de las metas de la moderna quimioterapia anticancerosa es el hallazgo de un an&#225;logo a la bleomicina con un mejor &#237;ndice terap&#233;utico que reduzca particularmente su efecto pulmonar&#46;</p></span>"
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000001600000003/v1_201509151256/S0300289615324832/v1_201509151256/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "43822"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Referatas"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000001600000003/v1_201509151256/S0300289615324832/v1_201509151256/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615324832?idApp=UINPBA00003Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Cytotoxic drug-induced pulmonary disease: Update 1980
Read
2797
Times
was read the article
1205
Total PDF
1592
Total HTML
Share statistics
 array:23 [
  "pii" => "S0300289615324832"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)32483-2"
  "estado" => "S300"
  "fechaPublicacion" => "1980-07-01"
  "aid" => "72552"
  "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica"
  "copyrightAnyo" => "1980"
  "documento" => "simple-article"
  "crossmark" => 0
  "subdocumento" => "abs"
  "cita" => "Arch Bronconeumol. 1980;16:135"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 913
    "formatos" => array:3 [
      "EPUB" => 44
      "HTML" => 487
      "PDF" => 382
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615324844"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32484-4"
    "estado" => "S300"
    "fechaPublicacion" => "1980-07-01"
    "aid" => "72553"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "abs"
    "cita" => "Arch Bronconeumol. 1980;16:135"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 910
      "formatos" => array:3 [
        "EPUB" => 43
        "HTML" => 452
        "PDF" => 415
      ]
    ]
    "es" => array:8 [
      "idiomaDefecto" => true
      "titulo" => "Small Cel Carcinoma of the Lung&#46; Experience with a six-drug Regimen"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => "es"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "135"
        ]
      ]
      "contieneResumen" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615324844?idApp=UINPBA00003Z"
    "url" => "/03002896/0000001600000003/v1_201509151256/S0300289615324844/v1_201509151256/es/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S0300289615324820"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32482-0"
    "estado" => "S300"
    "fechaPublicacion" => "1980-07-01"
    "aid" => "72551"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "abs"
    "cita" => "Arch Bronconeumol. 1980;16:135"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1052
      "formatos" => array:3 [
        "EPUB" => 45
        "HTML" => 579
        "PDF" => 428
      ]
    ]
    "es" => array:8 [
      "idiomaDefecto" => true
      "titulo" => "Anaerobic pleural and pulmonary infections"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => "es"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "135"
        ]
      ]
      "contieneResumen" => array:1 [
        "es" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615324820?idApp=UINPBA00003Z"
    "url" => "/03002896/0000001600000003/v1_201509151256/S0300289615324820/v1_201509151256/es/main.assets"
  ]
  "es" => array:8 [
    "idiomaDefecto" => true
    "titulo" => "Cytotoxic drug-induced pulmonary disease&#58; Update 1980"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "135"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "tieneResumen" => true
    "resumen" => array:1 [
      "es" => array:1 [
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La administraci&#243;n de algunos citost&#225;ticos se asocia a neumon&#237;a intersticial&#44; alveolitis y fibrosis pulmonar&#46; Algunos de ellos&#58; bleomicina&#44; busulf&#225;n&#44; metothrexate&#44; ya son conocidos como causantes de tales problemas y otros como el clorambucil&#44; la mitomicina y las mostazas nitrogenadas s&#243;lo se han reconocido recientemente&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La interacci&#243;n entre estas drogas y la radiaci&#243;n tor&#225;cica o la administraci&#243;n de ox&#237;geno a altas concentraciones ha producido neumonitis a dosis menores que cuando la droga se administra aisladamente&#46; El sinergismo entre diferentes drogas produce igualmente toxicidad pulmonar a dosis menores&#46; Con algunas drogas y en algunos pacientes&#44; los esteroides disminuyen las anomal&#237;as pulmonares&#44; pero la muerte por hipoxia sigue siendo frecuente&#46; El mejor tratamiento consiste en reconocer el problema y eliminar la droga&#44; por lo que es necesario que el m&#233;dico conozca los efectos de estos medicamentos&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Una de las metas de la moderna quimioterapia anticancerosa es el hallazgo de un an&#225;logo a la bleomicina con un mejor &#237;ndice terap&#233;utico que reduzca particularmente su efecto pulmonar&#46;</p></span>"
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000001600000003/v1_201509151256/S0300289615324832/v1_201509151256/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "43822"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Referatas"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000001600000003/v1_201509151256/S0300289615324832/v1_201509151256/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615324832?idApp=UINPBA00003Z"
]
Article information
ISSN: 03002896
Original language: Spanish
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 5 3 8
2024 October 35 14 49
2024 September 22 15 37
2024 August 40 25 65
2024 July 26 21 47
2024 June 28 15 43
2024 May 32 19 51
2024 April 29 14 43
2024 March 34 16 50
2024 February 39 25 64
2024 January 0 1 1
2023 November 0 1 1
2023 October 0 4 4
2023 August 0 3 3
2023 July 0 14 14
2023 June 0 2 2
2023 May 0 1 1
2023 March 10 2 12
2023 February 20 19 39
2023 January 21 18 39
2022 December 23 21 44
2022 November 36 13 49
2022 October 39 41 80
2022 September 61 13 74
2022 August 44 30 74
2022 July 27 28 55
2022 June 45 26 71
2022 May 50 20 70
2022 April 35 32 67
2022 March 63 29 92
2022 February 33 18 51
2022 January 23 22 45
2021 December 16 27 43
2021 November 11 20 31
2021 October 16 21 37
2021 September 11 23 34
2021 August 14 10 24
2021 July 11 13 24
2021 June 12 14 26
2021 May 10 15 25
2021 April 10 22 32
2021 March 10 8 18
2021 February 31 9 40
2021 January 12 17 29
2020 December 16 5 21
2020 November 8 12 20
2020 October 14 4 18
2020 September 11 8 19
2020 August 17 11 28
2020 July 10 16 26
2020 June 8 8 16
2020 May 12 9 21
2020 April 12 5 17
2020 March 10 15 25
2020 February 13 11 24
2020 January 26 11 37
2019 December 14 16 30
2019 November 1 4 5
2019 October 19 2 21
2019 September 5 14 19
2019 August 6 9 15
2019 July 11 18 29
2019 June 13 8 21
2019 May 11 28 39
2019 April 11 8 19
2019 March 9 11 20
2019 February 4 5 9
2019 January 5 3 8
2018 December 7 7 14
2018 November 2 7 9
2018 October 18 5 23
2018 September 4 4 8
2018 May 4 1 5
2018 April 17 8 25
2018 March 9 4 13
2018 February 8 11 19
2018 January 11 10 21
2017 December 5 13 18
2017 November 3 10 13
2017 October 7 8 15
2017 September 7 5 12
2017 August 13 9 22
2017 July 7 4 11
2017 June 6 12 18
2017 May 10 5 15
2017 April 7 5 12
2017 March 5 4 9
2017 February 4 4 8
2017 January 2 6 8
2016 December 7 5 12
2016 November 11 12 23
2016 October 9 10 19
2016 September 4 10 14
2016 August 11 5 16
2016 July 15 8 23
2016 June 12 6 18
2016 May 26 17 43
2016 April 8 1 9
2016 March 7 2 9
2016 February 11 5 16
2016 January 15 3 18
2015 December 18 9 27
2015 November 23 4 27
2015 October 7 1 8
2015 September 2 0 2
Show all

Follow this link to access the full text of the article

Archivos de Bronconeumología

Are you a health professional able to prescribe or dispense drugs?