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Síndrome hepatopulmonar en paciente con adenocarcinoma de colon con metástasis hepáticas y sin hepatopatía crónica conocida
Hepatopulmonary Syndrome in a Patient With Adenocarcinoma of the Colon Metastatic to the Liver and No Apparent Chronic Liver Disease
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Hospital Clínico Universitario de Valencia. Valencia. España" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Interna. Hospital Clínico Universitario de Valencia. Valencia. España" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondencia: Dr. B. Vila. Hospital Clínico Universitario de Valencia. Avda. Vicente Blasco Ibáñez, 17. 46010 Valencia. España." ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Hepatopulmonary Syndrome in a Patient With Adenocarcinoma of the Colon Metastatic to the Liver and No Apparent Chronic Liver Disease" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2005-11-07" "fechaAceptado" => "2005-12-27" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec153167" "palabras" => array:4 [ 0 => "Síndrome hepatopulmonar" 1 => "Vasodilatación pulmonar" 2 => "Hepatopatía" 3 => "Adenocarcinoma de colon" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec153166" "palabras" => array:4 [ 0 => "Hepatopulmonary syndrome" 1 => "Pulmonary vasodilation" 2 => "Liver disease" 3 => "Adenocarcinoma of the colo" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El síndrome hepatopulmonar comprende una tríada clínica caracterizada por desoxigenación arterial, dilataciones vasculares intrapulmonares y hepatopatía. Se han descrito tanto casos agudos como crónicos, y la causa más frecuente es la cirrosis. El mecanismo fisiopatológico principal es la dilatación de los vasos pulmonares, que produce una alteración del intercambio gaseoso. Se ha implicado la mayor producción pulmonar de óxido nítrico como mecanismo patogénico principal de la vasodilatación, aunque también se ha relacionado el desequilibrio entre sustancias vasodilatadoras y vasoconstrictoras. Describimos un caso en el que se produjo un síndrome hepatopulmonar en un paciente afectado de un adenocarcinoma de colon con metástasis hepaticas en un hígado previamente sano.</p>" ] "en" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Hepatopulmonary syndrome consists of a clinical triad: arterial blood deoxygenation, intrapulmonary vasodilation, and liver disease. Both acute and chronic cases of this syndrome have been reported, and the most common cause is cirrhosis. The principle disease mechanism is dilation of the pulmonary blood vessels causing alterations in gas exchange. Increased pulmonary production of nitric acid has been implicated as the primary pathogenic mechanism of vasodilation although it has also been associated with imbalance between vasodilators and vasoconstrictors. We describe the case of a patient with hepatopulmonary syndrome and adenocarcinoma of the colon with metastases to a previously healthy liver.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:18 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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Article information
ISSN: 03002896Original language: Spanish
DOI:10.1157/13092419
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| 2024 November | 4 | 2 | 6 |
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| 2024 February | 28 | 24 | 52 |
| 2024 January | 0 | 3 | 3 |
| 2023 November | 0 | 4 | 4 |
| 2023 October | 0 | 5 | 5 |
| 2023 August | 0 | 3 | 3 |
| 2023 July | 0 | 40 | 40 |
| 2023 June | 0 | 2 | 2 |
| 2023 May | 0 | 1 | 1 |
| 2023 April | 0 | 2 | 2 |
| 2023 March | 2 | 1 | 3 |
| 2023 February | 17 | 17 | 34 |
| 2023 January | 19 | 20 | 39 |
| 2022 December | 57 | 21 | 78 |
| 2022 November | 26 | 23 | 49 |
| 2022 October | 23 | 20 | 43 |
| 2022 September | 22 | 30 | 52 |
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| 2021 August | 10 | 42 | 52 |
| 2021 July | 27 | 45 | 72 |
| 2021 June | 21 | 48 | 69 |
| 2021 May | 17 | 32 | 49 |
| 2021 April | 19 | 116 | 135 |
| 2021 March | 27 | 25 | 52 |
| 2021 February | 54 | 26 | 80 |
| 2021 January | 29 | 23 | 52 |
| 2020 December | 14 | 28 | 42 |
| 2020 November | 19 | 26 | 45 |
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| 2020 September | 27 | 21 | 48 |
| 2020 August | 20 | 21 | 41 |
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| 2020 June | 15 | 17 | 32 |
| 2020 May | 26 | 20 | 46 |
| 2020 April | 26 | 19 | 45 |
| 2020 March | 24 | 24 | 48 |
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| 2020 January | 32 | 17 | 49 |
| 2019 December | 26 | 29 | 55 |
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| 2019 May | 32 | 43 | 75 |
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| 2019 January | 6 | 13 | 19 |
| 2018 December | 11 | 16 | 27 |
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| 2018 September | 15 | 10 | 25 |
| 2018 May | 7 | 2 | 9 |
| 2018 April | 11 | 6 | 17 |
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| 2017 April | 10 | 6 | 16 |
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| 2016 December | 12 | 6 | 18 |
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| 2016 February | 11 | 4 | 15 |
| 2016 January | 26 | 12 | 38 |
| 2015 December | 26 | 17 | 43 |
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| 2015 October | 158 | 1 | 159 |
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| 2015 May | 193 | 0 | 193 |
| 2015 April | 163 | 0 | 163 |
| 2015 March | 192 | 0 | 192 |
| 2015 February | 231 | 0 | 231 |
| 2015 January | 142 | 0 | 142 |
| 2014 December | 137 | 0 | 137 |
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| 2014 October | 184 | 0 | 184 |
| 2014 September | 116 | 0 | 116 |
| 2014 August | 123 | 0 | 123 |
| 2014 July | 93 | 0 | 93 |
| 2014 June | 120 | 0 | 120 |
| 2014 May | 146 | 0 | 146 |
| 2014 April | 118 | 0 | 118 |
| 2014 March | 138 | 0 | 138 |
| 2014 February | 107 | 0 | 107 |
| 2014 January | 118 | 0 | 118 |
| 2013 December | 110 | 0 | 110 |
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| 2013 August | 128 | 0 | 128 |
| 2013 July | 104 | 0 | 104 |
| 2013 June | 92 | 0 | 92 |
| 2013 May | 87 | 0 | 87 |
| 2013 April | 56 | 0 | 56 |
| 2013 March | 15 | 0 | 15 |
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