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Vol. 31. Issue 2.
Pages 89-92 (February 1995)
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Vol. 31. Issue 2.
Pages 89-92 (February 1995)
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Bronquiolitis obliterante con neumonía organizada (síndrome Ardystil) y enfermedad desmielinizante crónica del sistema nervioso central
Bronchiolitis obliterans organizing pneumonia (Ardystyl syndrome) and chronic demyelinating disease of the central nervous system
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P. Cordero, A. Solé*
Servicio de Neumología. Hospital Universitario La Fe. Valencia
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Se presenta el caso de una mujer de 19 años con bronquiolitis obliterante con neumonía organizada (BONO) secundaria a la inhalación de agentes tóxicos en ambiente laboral (síndrome Ardystil) y enfermedad desmielinizante crónica del sistema nervioso central. El diagnóstico de sospecha de la neumopatía se estableció ante la presencia de un cuadro clinicorradiológico compatible con BONO y se confirmó por biopsia transbronquial. El diagnóstico de enfermedad desmielinizante crónica del sistema nervioso central se efectuó por la presencia de sintomatología de disfunción neurológica transitoria junto con la existencia de hallazgos radiológicos compatibles en la resonancia magnética nuclear cerebral. La coexistencia temporoespacial en nuestra paciente de las dos enfermedades abre la posibilidad de la aparición de un nuevo síndrome secundario a la inhalación de sustancias tóxicas o la mera coincidencia de dos enfermedades poco frecuentes en nuestro medio.

Palabras clave:
Bronquiolitis obliterante con neumonía organizada
Síndrome Ardystil
Enfermedad desmielinizante crónica

A 19-years-old Human with bronchiolitis obliterans organizing pneumonia (BOOP) secundan to inhalation of toxins in the workplace (Ardystil syndrome) and chronic demyelinating disease of the central nervous System is described. The clinical and radiological picture led to suspicion of BOOP and the diagnosis was confirmed by transbronchial biopsy. The diagnosis of chronic demyelinating disease of the central nervous System was based on the presence of signs of transitory neurological dysfunction along with nuclear magnetic resonance images of the brain that were consistent with the clinical evaluation. The temporal and spatial concurrence of the two diseases in our patient suggests that we may be observing either a new syndrome associated with the inhalation of toxic substances or a coincidence of two diseases that are rare in the population we serve.

Key words:
Bronchiolitis obliterans organizing pneumonia
Ardystil syndrome
Chronic demyelinating disease
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Copyright © 1995. Sociedad Española de Neumología y Cirugía Torácica
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