Journal Information
Vol. 20. Issue 5.
Pages 210-215 (September - October 1984)
Share
Share
Download PDF
More article options
Vol. 20. Issue 5.
Pages 210-215 (September - October 1984)
Full text access
Participacion de analgesicos y colorantes en el asma bronquial
Role of dyes and analgesic drugs in bronchial asthma
Visits
5026
A. Sanchez Palacios, A. Quintero De Juana
Sección de Alergología. Residencia Sanitaria Onésimo Redondo. Valladolid
This item has received
Article information
Abstract
Bibliography
Download PDF
Statistics

Se estudia la participación de colorantes azo-compuestos y analgésicos antiinflamatorios no esteroideos en el asma bronquial.

El síndrome clínico que se asocia a la intolerancia de colorantes y analgésicos se caracteriza por ser un asma bronquial intrínseco corticodependiente con sinusitis, poliposis y una mayor frecuencia en mujeres.

Se revisan las diferentes teorías etiopatogénicas de este síndrome, aceptándose la de que los analgésicos y colorantes inhiben la síntesis de prostaglandinas.

Por último, se presentan los alimentos y medicamentos que contienen colorantes capaces de producir reacciones adversas.

The role of azo-compound dyes and analgesic antiinflammatory non-steroidal drugs in bronchial asthma is studied.

The clinical syndrome associated to intolerance to dyes and analgesic drugs is characterized by intrinsec, cortico-dependent bronchial asthma with sinusitis, polyposis and female predominance.

The different etiopathogenetical theories of this syndrome are reviewed. It is accepted that dyes and analgesic drugs inhibit the synthesis of prostaglandins.

Finally, foods and drugs containing dyes involved in adverse reactions are presented.

Full text is only aviable in PDF
Bibliografia
[1.]
M. Samter.
Intolerance to aspirin.
Hosp Prac, 8 (1973), pp. 58-63
[2.]
M. Samter, R.F. Beers.
Concerning the nature of intoleran ce to aspirin.
J Allergy, (1967), pp. 281-293
[3.]
F.H. Chafee, G.A. Settipane.
Aspirin intolerance I. Frequency in an allergic population.
J Allergy Clin Immunol, 53 (1974), pp. 193-198
[4.]
R.F. Loche, D.L. Rucknagel, N.A. Vanselow.
Familial occurrence of asthma, nasal polyps and aspirin intolerance.
Ann Intern Med, 78 (1973), pp. 57-63
[5.]
D.G. Von Maur, P. Norman.
Aspirin intolerance in a family.
J Allergy Clin Immunol, 54 (1974), pp. 380-395
[6.]
J.W. Yunginger, E.J. O’Connell, G.B. Logan.
Aspirininduced asthma in children.
J Pediatr, 82 (1973), pp. 218
[7.]
F.F. Miller.
Aspirin-induced bronchial asthma in sisters.
Ann Allergy, 29 (1971), pp. 263-268
[8.]
J.C. Delaney.
Pentazocine bronchospasm.
Lancet, 2 (1972), pp. 338
[9.]
Bernstein IL, Gallagher JS, Johnson H, Archer D, Splansky GL. Evaluation of immunologic and non immunologic factors in the pathogenesis of adverse reactions to tartrazine. En: Proccedings of the FDA 4th Science Symposium: Inadertent modification of the immune response. Annapolis MA 1980 (en prensa).
[10.]
R.S. Farr, S.L. Spector, C.H. Wangaard.
Evaluation of as pirin and tartrazine idiosyncrasy.
J Allergy Clin Immunol, 64 (1979), pp. 667-668
[11.]
A.F. Gentry, R. Schwartz, J. Bauman.
Tartrazine containing drugs.
Drug Intell Clin Pharm, 15 (1981), pp. 782-788
[12.]
R. Cesarini, M. Colombo, M. Robuschi, S. Bianco.
Tartrazine and prostaglandina, system prostaglandina.
Medici ne, 1 (1978), pp. 499-510
[13.]
E. Rogert, M.D. Desmond, J.J. Trautlein.
Tartrazine (FDC Yellow 5) anaphylaxis: a case report.
Ann of Allergy, 46 (1981), pp. 81-85
[14.]
B.S.M. Stenius, M. Lemola.
Hypersensitivity to acetylsalicylic acid and tartrazine in patients with asthma.
Clin Allergy, 6 (1976), pp. 119-129
[15.]
N. Weliky, D.C. Heiner.
Hypersensitivity to chemicals. Correlation of tartrazine hypersensitivity with caracterictic se rum IgD and IgE immune response patterns.
Clinical Allergy, 10 (1980), pp. 375-394
[16.]
S.M. Tarlo, I. Broder.
Tartrazine benzoate challenge and dietary avoidance in troublesome asthma.
J Allergy Clin Immu nol, 65 (1980), pp. 226-236
[17.]
W.R. Starr.
Familial aspirin hypersensitivity.
Ann Allergy, 29 (1971), pp. 498
[18.]
A. Szczeklik, R.J. Gryglewski, G. Czerniawska-Mysik, A. Zmuda.
Aspirin induced asthma-hypersensitivity to fenoprofen and ibuprofen in relation to their inhibitory action on prostaglandin generation by different enzyme preparations.
J Allergy Clin Immunol, 58 (1976), pp. 10-18
[19.]
G.A. Settipane, F.H. Chafee, D.E. Klein.
Aspirin intolerance II. A prospective study in an atopic and normal population.
J Allergy Clin Immunol, 53 (1974), pp. 200-204
[20.]
M. Kaliner, S.I. Wasserman, K.F. Austen.
Immunologic re lease of chemical mediators from human nasal polyps.
N Engl J Med, 289 (1973), pp. 271-273
[21.]
J.A. Philis, L. Perimutter.
IgE mediated and non IgE mediated allergic type reactions to aspirin.
Acta Allergol, 29 (1974), pp. 474-490
[22.]
L. Juhlin, G. Michelsson, O. Zetterstrom.
Urticaria and asthma induced by food and drug additives in patients with as pirin hypersensitivity.
J Allergy Clin Immunol, 50 (1972), pp. 92-98
[23.]
E.W. Fisherman, G.N. Cohen.
Aspirin and other crossreacting small chemicals in known aspirin intolerant patients.
Ann Allergy, 31 (1973), pp. 476-477
[24.]
H.D. Schlumberger, E.A. Löbbecke, P. Kallós.
Aėtylsalicylic acid intolerance Lack of N-acetylsalicylic acid specific skin-sensitizing antibodies in the serum of intolerant indivi duals.
Acta Med Scand, 196 (1974), pp. 451-458
[25.]
J.R. Macdonald, D.A. Mathison, D.D. Stevenson.
Aspirin intolerance in asthma detection by oral challenge.
J Allergy Clin Immunol, 50 (1972), pp. 198-207
[26.]
A.M. Yurchak, K. Wicher, G.E. Arbesman.
Immunologic studies on aspirin.
J Allergy, 46 (1970), pp. 245-251
[27.]
G.M. Hänsch, V. Voigtlander, H. Rother.
Effect of aspi rin on the complement system in vitro.
Int Arch Allergy Appl Immun, 61 (1980), pp. 150-158
[28.]
J. Dry, A. Pradalier, J.P. Aubry.
A propos de la physiopathologie de l’asthma a l’aspirine Recherche d’un rôle evetuel de l’histamine, de la serotonine et les prostaglandines.
Rev Franc Allergol, 19 (1979), pp. 125-130
[29.]
R.J. Flower.
Aspirin-like drugs and prostaglandins.
Am Heart J, 86 (1973), pp. 844
[30.]
B. Smith, A.L. Willin.
Aspirin selectively inhibits prostaglandin production in human platelets.
Nature New Biol, (1971), pp. 231-235
[31.]
E.J. Goetzl.
Mediators of immediate hypersensitivity derived from arachidonic acid.
N Engl J Med, 303 (1980), pp. 822-823
[32.]
M. Samter, R.F. Beers.
Intolerance to aspirin; clinical studies and considerations to its pathogenesis.
Ann Intern Med, 68 (1968), pp. 975-983
[33.]
A.A. Mathe, P. Hedqvist, A. Holmgren, N. Svanborg.
Bronchial hyperreactivity to prostaglandin F2 and histamine in patients with asthma.
Br Med J, 1 (1973), pp. 193-196
[34.]
G.A. Settipane, R.K. Pudupakkam.
Aspirin intolerance III Subtypes familial occurrence and cross reactivity with tartrazine.
J Allergy Clin Immunol, 56 (1975), pp. 215-221
[35.]
M.F. Cuthbert.
Bronchodilatador activity of aerosols of prostaglandin E 1 and E 2 in asthmatic subjects.
Proc R Soc Med, 64 (1971), pp. 15-20
[36.]
A. Szczekvk, R.J. Gryglewski, G. Czerniawska-Mysik.
Realtionship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin sensitive patients.
Br Med J, 1 (1975), pp. 67-69
[37.]
B.N. Fredman.
Adiestary free from additives in the management of allergic disease.
Clin Allergy, 7 (1977), pp. 417-421
[38.]
L.J. Smith, R.G. Savlin.
Drugs containing tartrazine dye.
J. Allergy Clin Immunol, 58 (1976), pp. 456-470
[39.]
C.M. Arroyave.
Oral aspirin challenge in asthmatic pa tients; a study of plasma mediators.
J Allergy Clin Immunol, 57 (1976), pp. 206
[40.]
J.C. Delaney.
The diagnosis of aspirin idiosyncrasy by analgesic challenge.
Clin Allergy, 6 (1976), pp. 177-181
[41.]
I. Frazer, G. Settipane, S. Braman, B. Decorus.
Aspirin intolerance in a low risk population and its effects on methaboline challenge.
J Allergy Clin Immunol, 65 (1980), pp. 226-235
[42.]
N.A. Martelli.
Bronchial and intravenous provocation tests with indomethacin in aspirin-sensitive asthmatics.
Am Rev Respir Dis, 120 (1979), pp. 1073
[43.]
D.A. Mathson, D.A. Stevenson.
Hypersensitivity to nonsteroidal anti-inflammatory drugs: indications and methods for oral challenge.
J Allengy Clin Immunol, 64 (1979), pp. 669-674
[44.]
A.P. Smith.
Response of aspirin allergic patients to challenge by some analgesics in common use.
Br Med J, 2 (1971), pp. 494-496
[45.]
N.A. Vanselow, J.R. Smith.
Bronchial asthma induced by indomethacin.
Ann Inter Med, 66 (1967), pp. 567-568
[46.]
S. Blanco, M. Robuschi, G. Petrini.
Aspirin induced tolerance in aspirin-asthma detected by a new challenge test IRCS.
J Med Sci, 5 (1977), pp. 129-135
[47.]
W.W. Pleskow, D.A. Stevenson, D. Mathison, R. Simon, R. Zeiger, M. Schatz.
Aspirin desensitivation in aspirin-sensitive asthmatics: characterization on the refractary period.
J Allergy Clin Immunol, 65 (1980), pp. 204-226
[48.]
W. Warren, Pleskoww, D.D. Stevenson, D.A. Mathison, R.A. Simon, M. Schatz, R.S. Zeiger.
Aspirin desensitization in aspirin-sensitive asthmatic patients Clinical manifestations and characterization of the refractory period.
J Allergy Clin Immu nol, 69 (1982), pp. 11-19
[49.]
E. Alvarez Cuesta, F. Moneo Goiri, M. Sánchez Cano, M. Cuevas Agustín, E. Losada Cosmes.
Síndrome de intoleran cia al ácido acetilsalicílico ¿Qué prescribir?.
Allergol et Immunopathol, 94 (1981), pp. 313-318
Copyright © 1984. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?