Estudios reologicos del esputo con metodos capilares

Oteo Ochoa, L.A.; Ruiz Mateo, A.; Izquierdo Del Amo, A.; Delgado Perez, E.; De La Cruz, J.L.; Sueiro Bendito, A.

doi:10.1016/S0300-2896(15)32272-9

Archivos de Bronconeumología

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Vol. 20. Issue 1.

Pages 34-45 (January - February 1984)

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Pages 34-45 (January - February 1984)

DOI: 10.1016/S0300-2896(15)32272-9

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Estudios reologicos del esputo con metodos capilares

Rheological studies of sputum with capillary methods

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L.A. Oteo Ochoa, A. Ruiz Mateo*, A. Izquierdo Del Amo, E. Delgado Perez, J.L. De La Cruz, A. Sueiro Bendito

Servicio de Neumología. Centro Especial Ramón y Cajal. Madrid

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Se analizaron 28 muestras de esputo original pertenecientes a los cuatro tipos de STB establecidos. Para su estudio reológico se utilizó un sistema de viscosimetría capilar (Rheomatic-Viskosimeter-Moleculex) previamente estandarizado. Sin previa manipulación física del esputo fresco, las curvas reológicas obtenidas en función de las variables shear rate versus shear stress eran fiel reflejo del carácter heterogéneo de la STB. Este comportamiento heterogéneo del espécimen original es la causa fundamental que encubre sus principales características reoló-gicas. Tras un procedimiento de laminación transcapilar en diferentes estados de stress se obtuvieron reogramas mensurables que representaban un perfil de fluido homogéneo no newtoniano, siendo por otra parte más expresivo el fenómeno cuanto mayor era el shering. Bajo estas condiciones físicas varias muestras biológicas tipa-das como mucopurulentas y purulentas aproximaban un rango de conducta reológica a la categoría de los fluidos newtonianos para G = 25-90 s–1.

Se comparó la viscosidad aparente (G = 25 s–1) del esputo original y tras manipulación física mediante procedimiento de laminado, analizándose los resultados obtenidos.

28 samples of original sputum from the four es-tablished STB types were analyzed. For rheological study a previously standardized «capillary viscosimetry» sys-tem (Rheomatic-Viskosimeter-Moleculex) was used. Without previous physical manipulation of fresh sputum, rheological curves obtained from the variables shear rate versus shear stress faithfully reflected the hete-rogeneous character of STB. This heterogeneous behaviour of the original specimen is the fundamental mecha-nism whereby its main rheological features are masked. After a procedure of transcapillary lamination in diffe-rent states of stress, mensurable rheograms were obtained representing a homogeneous non-newtonian fluid profile. This phenomenon was more marked as the she-aring was greater. Under these physical conditions, the range of rheological behaviour of several biological samples classified as «mucopurulent» and «purulent» approached newtonian fluids for (G = 25—90 s–1).

Apparent viscosity (G = 25 s–1) of original sputum was compared; after physical manipulation with a lamination procedure, a comparison between results was carried out.

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