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Vol. 53. Num. 10.October 2017
Pages 535-602
Vol. 53. Num. 10.October 2017
Pages 535-602
Clinical Image
DOI: 10.1016/j.arbr.2017.08.010
Deferred Locoregional Recurrence of Pleural Mesothelioma
Recidiva locorregional diferida de mesotelioma pleural
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Francisco Javier García-Gómeza,
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javier191185@gmail.com

Corresponding author.
, Teresa García-Manriqueb, Juan Castro-Montañoa
a Servicio de Medicina Nuclear, Hospital Universitario Virgen Macarena, Sevilla, Spain
b Servicio de Oncología Médica, Hospital Universitario Virgen Macarena, Sevilla, Spain
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Malignant mesothelioma is a mesodermal tumor that originates in the serous membrane of the pleura, peritoneum, and, occasionally, the pericardium and tunica vaginalis of the testes. Relapse is generally locoregional, with invasion of adjacent tissues, but hematogenous metastatic dissemination has very occasionally been described.1 Musculoskeletal recurrence after a long disease-free period is extremely rare, with few cases reported in the literature.1,2

We report the case of a 54-year-old patient with a history of pleuropneumectomy, phrenicectomy, and pericardiectomy for left pleural mesothelioma, with metastatic splenectomy 2 years later. After a disease-free period of 14 years, computed tomography revealed small mediastinal lymphadenopathies and a solid nodule with polylobulated contours in the sheath of the rectus abdominus muscles. PET-CT extension scan with 18FDG showed hypermetabolic lesions (Fig. 1, arrows) in the lymph nodes, mediastinum, and muscle planes of the left serratus anterior muscle, rib cage and the left rectus anterior muscle of the abdomen (Fig. 1, asterisk), in which a maximum SUV of 5.7 was recorded. Infiltrating epithelial mesothelioma was confirmed by abdominal muscle biopsy, and treatment started with cisplatin-pemetrexed.

Fig. 1.
(0.23MB).

Maximum intensity projection (MIP) image and axial slices from the 18FDG PET-CT, showing hypermetabolic deposits of tracer in the mediastinal lymph nodes and locoregional deposits in the left serratus anterior muscle, the rib cage, and left rectus anterior abdominus (arrows), and changes resulting from surgical history in the left hemithorax. The lesion with the highest metabolic rate was located in the left rectus anterior abdominus (asterisk), with SUVmax 5.7.

Although the possibility is remote, diffuse locoregional recurrence should be considered in a patient with a history of malignant pleural mesothelioma, so that prompt and effective treatment can be offered.

References
[1]
S. Akyurek,M. Nalca Andrieu,A. Hicsonmez,S. Dizbay Sak,C. Kurtman
Skeletal muscle metastasis from malignant pleural mesothelioma
Clin Oncol (R Coll Radiol), 16 (2004), pp. 585
[2]
A. Bille,S. Chicklore,L. Okiror,G.J. Cook,J. Spicer,D. Landau
Patterns of disease progression on 18F-fluorodeoxyglucose positron emission tomography-computed tomography in patients with malignant pleural mesothelioma undergoing multimodality therapy with pleurectomy/decortication
Nucl Med Commun, 34 (2013), pp. 1075-1083 http://dx.doi.org/10.1097/MNM.0b013e3283653862

Please cite this article as: García-Gómez FJ, García-Manrique T, Castro-Montaño J. Recidiva locorregional diferida de mesotelioma pleural. Arch Bronconeumol. 2017;53:584–585.

Copyright © 2017. SEPAR
Idiomas
Archivos de Bronconeumología (English Edition)

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