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Vol. 20. Issue 5.
Pages 181-187 (September - October 1984)
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Vol. 20. Issue 5.
Pages 181-187 (September - October 1984)
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Operabilidad en el carcinoma broncogenico. Valoracion por estudio gammagrafico pulmonar de perfusion, cuantitativo y diferencial
Operability in bronchogenic carcinoma. Evaluation with scintigraphic perfusion, qualitative and differential studies
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A. Lopez-Encuentra, G. Varela, P. Martin-Escribano, J. Toledo, M. Gutierrez, A. Manrique, J. Diaz-Atauri
Secciones de Neumología y Cirugía Torácica. Servicio de Medicina Nuclear. Ciudad Sanitaria Primero de Octubre. Madrid
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El problema de la tolerancia funcional a una neumo-nectomía es valorado en este estudio mediante la cuantificación diferencial de la perfusión pulmonar por metodología isotópica calculando el VEMS previsto postoperatorio. Siguiendo técnicas ya descritas, en una serie de 128 pacientes con carcinoma broncogénico protocolizados prospectivamente desde 1978 a 1982, en 10 pacientes se decidió inoperabilidad por encontrar un VEMS calculado postoperatorio menor de 800 ce; la correlación entre el VEMS calculado por esta técnica y el real postoperatorio hallado es alta en nuestra experiencia (r:0,93). En catorce neumonectomías de pacientes con VEMS real preoperatorio menor de 2.000 ce, que superaban el criterio anteriormente expuesto, uno fallecía en el período postoperatorio inmediato (7,1%). Este nivel de mortalidad operatoria es similar a poblaciones neumonectomizadas por carcinoma broncogénico sin ser seleccionadas por criterio funcional.

Teniendo presentes estos datos en relación a un valor absoluto del VEMS como límite de operabilidad, se efectúan diversas consideraciones acerca de si otros parámetros como el porcentaje del VEMS con respecto al teórico y la combinación con estudios hemodinámicos, pueden en el futuro ser índices mas exactos de predicción del riesgo operatorio.

The problem of the functional tolerance to pneumo-nectomy is evaluated in the present study by means of differential quantification of pulmonary perfusion by radioisotopic studies and calculation of predicted postoperative FEV1. Using already described techniques, in a series of 128 patients with bronchogenic carcinoma pros-pectively undergoing a protocol study from 1978 to 1982, inoperability was decided on the basis of a calculated postoperative FEV1 of less than 800 cc. In our experience, the correlation between the FEV1 as calculated by this technique and the real postoperative values in high (r:0.93). In 14 pneumonectomies in patients with real postoperative FEV1 of less than 2000 cc (exceeding the above mentioned criteria), 1 patient died in the imme-diate postoperative period (7.1%). This rate of postoperative mortality is similar to that seen in populations undergoing pneumonectomy for bronchogenic carcinoma and not being selected on the basis of functional criteria.

In view of these data related to an absolute value of FEV1 as a limit to Operability, some considerations are developed as to whether other parameters, such as the ratio of FEV1 to its predicted value and the combination with hemodynamic studies, may be in the future more occurate predictors of operative risk.

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Copyright © 1984. Sociedad Española de Neumología y Cirugía Torácica
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