TY - JOUR T1 - Prevalence of COPD in 6 Urban Clusters in Argentina: The EPOC.AR Study JO - Archivos de Bronconeumología T2 - AU - Echazarreta,Andrés L. AU - Arias,Sergio J. AU - del Olmo,Ricardo AU - Giugno,Eduardo R. AU - Colodenco,Federico D. AU - Arce,Santiago C. AU - Bossio,Juan C. AU - Armando,Gustavo AU - Soriano,Joan B. SN - 15792129 M3 - 10.1016/j.arbr.2017.09.017 DO - 10.1016/j.arbr.2017.09.017 UR - https://archbronconeumol.org/en-prevalence-copd-in-6-urban-articulo-S157921291830082X AB - IntroductionThe prevalence of chronic obstructive pulmonary disease (COPD) has not been studied in Argentina. ObjectivesTo determine the prevalence and relevant clinical characteristics of COPD in a representative sample. Material and methodsWe performed a cross-sectional study in a population of adults aged ≥40 years randomly selected by cluster sampling in 6 urban locations. Subjects answered a structured survey and performed pre- and post-bronchodilator spirometry (PBD). COPD was defined as FEV1/FVC ratio <0.7 predicted value. The total prevalence was estimated for each cluster with its 95% confidence interval (CI). ResultsOf 4599 surveys and 3999 spirometries, 3469 were considered of adequate quality (86.8%) for our study. The prevalence of COPD was 14.5% (CI: 13.4–15.7). The distribution of COPD cases according to FEV1 (GOLD 2017) was stage 1: 38% (CI: 34–43); stage 2: 52% (CI: 47–56); stage 3: 10% (CI: 7–13); and stage 4: 1% (CI: 0–2), and according to the refined ABCD (GOLD 2017) assessment: A: 52% (CI: 47–56); B: 43% (CI: 39–48); C: 1% (CI: 0–2); D: 4% (CI: 2–6). The rate of underdiagnosis was 77.4% (CI: 73.7%–81.1%) and diagnostic error 60.7% (CI: 55.1%–66.3%). A significant association was found between COPD and age (OR 3.77 in individuals 50–59 years of age and 19.23 in those >80 years), male gender (OR 1.62; CI: 1.31–2), smoking (OR 1.95; CI: 1.49–2.54), low socioeconomic status (OR 1.33; CI: 1.02–1.73), and previous tuberculosis (OR 3.3; CI: 1.43–7.62). ConclusionsWe estimate that more than 2.3 million Argentineans have COPD, with high rates of underdiagnosis and diagnostic error. ER -